HsaINT0088699 @ hg19
Intron Retention
Gene
ENSG00000213160 | KLHL23
Description
kelch-like 23 (Drosophila) [Source:HGNC Symbol;Acc:27506]
Coordinates
chr2:170597895-170606438:+
Coord C1 exon
chr2:170597895-170598047
Coord A exon
chr2:170598048-170605931
Coord C2 exon
chr2:170605932-170606438
Length
7884 bp
Sequences
Splice sites
5' ss Seq
CAGGTAACA
5' ss Score
8.88
3' ss Seq
TCTTTTTTTCTTTTTAAAAGAAT
3' ss Score
7.38
Exon sequences
Seq C1 exon
GTGTGGGAAATGCTACTGCCTGTGTCTTACATGATGTTATCTACGTCATTGGTGGCCACTGTGGCTACAGAGGAAGCTGCACCTATGACAAAGTTCAGAGCTACAATTCCGATATCAACGAATGGAGCCTCATCACCTCCAGTCCACATCCAG
Seq A exon
GTAACAAAAATACTGTCTCAAATAGTGTATGTTGTGATGTAGTTTAGTAGCATAAAGGATGGCTAAAAATGGACTGGAAATAGAAAATGCTGATTTTATTGTAGACTACACATGGGTAGAATTAAAAGTCTCAAAATATTCATATATGTCCATCTAACAATAATCACAATGAGATTCTGATTGGGTCACATCTACAAATATTTTCCCTGATGTCTTTATACAATGCACATTGTAAGTCTGTGTGGTCAAAAATATTAGCGTCTTTAAAATTTTTTTCCTTTATATGCCATCTTTCATTTATGACATTAATTATATAAAATACAATGTTCATAAGTAGTTGAAAAGCACCATTCTATCAAATAGTCAGAAAGGGTACCCAGTGATTGAAGTTCAGCTAGAAATTGTTTCCTGTTTTAGAAGCATGTTCTTTCTAGGTTTCACTTACTATTAAGCACTCACTCCTACAATGTGCAGAGCCATATGTTGGCCTTACCTTAACACTCATACAGGGAACATGCTGTCTGCCCATAAGGAATGGCCTACCTTCTTGGATGTCTTCTGTTCTTTGACTTGTGTCTTTGTGAAGAGCTCAGAGGGAAGCACAAGTTTTAGTCTGTTTCAGTTATGCCATAGGTTTAAGTTGTTTTCATTAGGAAAGATTCATATCATCGTACCACCATGTTACCTTGAATCATTTTCCATAGAGCATCAGGCTTCCATGTGGGTCAGTGGAGGGGGTAGTGGAAATTCACAAGCTGGAACCATCTGAGAGGACTAGTAATACTTACCATAGATCAGGCACTGGCTAAGCACTTCATATGTGTATTACCTCAGATTCTCACTACAAGTCTGTGAGCAGGTATTGTTTGTCACCATTTTACATATTTGGAAATGGAGGCTTAGAAACAATAAGTAACTTTTCCAAGGTCACAGTTTCACAGTTTGAAAGTGGTAGACCAGGGTTCAAAATCTGACAGTCTGATTCCATAACTTGTGCTGTAGCCACTAAACAATCTGTCTCTCCTTCAGGGAGCAGACTCTCCTGCTTTCAACCAAGGCAGCTACTTCCAGCCCATACATCATCTATCCCATATGATGGTTAATCTGAAGCACACCTAAATCTGGTGCTGCATCTCCATATGCCCAGGCTTTGCATGAGAAGGAACTTTAGCCCCAGGCTTCCCTGGCTGCAAAGACACCATGGAATGGGTAAACTTCTCCCTCCTAGTAGCCCAAATGGACCATCCCAGACTCCCCACCACTTTCTGCTGTGATCAGTGAAGTTATAATGGAAAGGAATAGTAACAACTCACAGTGAGAAATAGCTAGCATTTATTCAGTCAGTGTGTGGCAGGCACAAACTATTCCAGTAATTTTACATGTATAATCTGTTTAAACCTCAAAATAATTCCATGAGCTAGGTACTGTTTTTATCACATTTTATAGGACACTGAGGGTCAAAGAGATTATATAAATTGCCCAAGGTTAGCCAGCTAGTGCTTATTAGAACTGAGGTTCAAACCTAGACAGACTGGCTTGAACTTCACTATTATCTCACCTGAACCTCATGTTACCCTTAGAAGTTAGATGTTACTCTGCCTATTTTGTGGATAAGCTTATCTTTACAAAGAAAATCCGATACATGAAAAGTCAGAATTCACAAATTAGAGGGCAGTTATTTATATTATAAATTTAATGTATATGTCATTAAGAGTTTCCCTCAAAAATAAGTTTTCCATAACAGATTTCATATAGCTTATTAACTACATGAAAAAGAGTCTGAGAGACAGTGTCACTTTGGACTTAATCCAAAGTATTAATAAGTCATGGCAAATTGAAAATCCAAAATAAATGTTAAATTATAATATAAATCAATGGTAACATAATATGCATCCACATGTAGTTTTGATTTACATTGAACTTTTTCCTGATGAAACATAAAAAACAGATTTTAAATCAGTACCTTGCATGATGTGTTCTGTTTAGCTTTCACAGTCCTTAAAATATTTTTGAACTGGCTTGTTACCAATATTTAAAATTTAAGAGAATTTCAAGTAAAAATCATTATTTCTGTCCTTTAAAAGAAAAGGGAAGACCTAGCAGCCTTGGATGTATTCCTTCTAGGCAGCAGTCACGGGAGCCAGGGGGTAGCTGTTCCCCTAAATGAGGCTTGTGTGCTCCGTTTCACCACAGTCCTTCCAATTCTCCTCACGTCACTGACCTAGGGGGCCTGTGCCGTTGTTTTTCTTGCTCCCAGCTGGCTTTGCTCAGCTAGTCTGTTAAATCCTTAAGCTCTTGAAGGCTGTGCATCTGCATCCACTGAATTATAGCAAGGTTTGTTTCTTAAGGATTTTAGCAGTACCTCCTGAGGAATTAAAATGTCATCCTTGAGTTGACTTCATAGAGATACATTGCTTACACTGAGAAGAAATGACTACTATTATTTTTTAAAGATAATATAAGTATTATATTTTATCTTAACCCCTTTAATGGGGTAGTTTGTGTAATTGGAAAACATGGGACTATAGTTGCATTGAATTCAAGGTGACATTTATTGAGACCCTACATTGGAAAAGGTAGGATTCTGATAATTATGTAAGATGATTAAGTGTTAGTCTTTACTGCCGTAGGAGCTCAGAATCCAGGAGCAAATATACATACATAATGGAAATACAGGACAGTCTCTGCTAAGTTCTGTAAAAACAAGTGCTATTGAAATTGAGAATAAAAAGAGTGTAAGTCTAATTAAGGGAAATCTGACTATCTTAGAATGCTTCCAACGGTAGGTGGTTATGAGCTGGGCCTTAAAGAATGGCCCCAAATAAGGAAGGTAGTTTTTGAGGAAGGGTTTTTCTGGCAAGAAGTCAGCCCAGTGGAGGAAGGTGGAAAGGAAAGTTTCAGGTGTATTCCATTACCTGGGAGCAGACATGAATGAATGGAATGTAAGAGGGTAGAATGGGAGATCGGATGGGAGAGTTCAGTTGGAGAGCATGTCATGGAGAGCTTTGAATGGCAGTCTGGGTAATTTTTTTTTTTTTTGAGATGGAGTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTAACCGCAACATCCGCATCCCAGGTTCAAGGTATTCTCCTGCCTCAACGTCCCAAGTAGCTGAGATTACAGGCGCTGCTACTTTGCCCGGCTAATTTTTCATATTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGCTGGTCTCAAACTCCTGACCTTGTGATTCACCTTCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCTTGAGCCACCACAACCAGCTCAGTCTGGGTAATTTTTAAAATGCAGAATCATAAAGGTTTTCGAGCAAGAGAATGATGTGTGATCAGCTCTAGGTTTTTGTTTTTTGTTTTTTTTTTTTTAAAGACAGTCTCGCTCTGTTGCTTAGGCTGGAGTGCAGTGGCACAATCTTGGGTTCAGCGATTCTTGTGTCTCAGCCTCCCAGGTAGCTGGGATTACAGGCATGCACCACCACGCCTGGCTAATTTTTGTATTTTTTTTTAGTAGAGACGGGGTTTCACTATGTTGGCCAGGCTGGTCTTGAACTCCTGGCCTAAAGTCATCCACCCGCCTCAGCCTCCCAAAGCACTGGGCCACTGCACCTGGCCCAGCTCTGGTTTTAAGAAGAGAACTCTTGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCTGCACTTTGGGAGGCCAAGGTGGGCGGATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAAATTAGCTGGGCATGGTGGCGGGCACCTGTAGTCCTAGCTACTCGGGAGGCTGAGCCAGGAGAATGGTGTGAACCCGGGAGGCAGAGCTTGCAGTGAGCTGAAGATCGTGCCCCTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAGGAAGAGAACTCCTTTTAGGTAGATTGGGAGAAAGACAGCAAGGGGATCTACTAACACTATTGTGTTTAACCAAGGGAGAAATGCTGAAAGCCTGAAGAAGTGGTAGGAGTAGAAAAGAGGGGCCGATGTGAGGAATGTCATAGATTCAACAGCTGATTGCTTCCTTGGCTGACAGCATACAGGAGATGAAGGAGAGAAAGGAGTTGACAGTCGTCTCAGGGTCTCTGGCCGGTTGTCTGAGAGAATGAGGTATACTGAAGGAGAAGCTGACAGGAAGGGAGAAGAGGGGAGATGATGAGCTCGATTTTATAGTTTAGAGCAAAGGAATCATTGGATAACCCAAAAGAGCTGTCCAGCAGGCAAAGGGAAATGTGGGTTTGCAGCTGAGAAGGAGGGAGGTAGCTGAATGTAGAGATCTGGGGATTGTTTGCTTGGATGGTGGCTCTGGGTATGGGGATGAATAAGATGCCTTGGTAGGGTGGGACCAGCAATACAGCTATGGGCAGAATCCTAGGAAACGGGCAGAGTTGAGGGATAAGCTGAGGAACAAGAGGGTGTGAAGAGCCGAGAGGAAGCAGTATGTGATAAAGGAGGACCTGTGGAGAGTTGTGTGAAGTGGGGAGAGAACTTTCCTGGCCCTGCCATTTATTTACCTGCCTTGCCATCGGCAAGTAGACTAAGCTCTTGGGCCTTACCTTCCAGTGAAATCAGAAAGTTAGACTACATAAACTTTACAGGCTCTTCAATGAGAAAAGATCTTAGGAAAAAAAATTGAAATCAATTCAAATGGATATTGTGGTTTTCTCTGAATCCCTCTAGCTGTTTGTTCATATCACTCATCTAACACTGAATACAGACTGCTGTGTGTTGATGTTTTATACTTCTGTGTAAACTTTTGAGCCGTGACAGATGGTGTCACTCCCATTCTTGATTATTCATTTGTTCACTCATTCATGTCTAACATATCTGCTGTGTGCATCCTACATGCTGCTATATACTCAGTGCTAGGAGCACAGTGAGCAAGGCACAGTCCCAGAGCCTCAGTGGCTTAGAGGGGTTAACTAACAAGAAAAAACGCAATTACAGCTCAGGAAGAAAAAGTTCCTATCCACAACAATAGAACATGTGTTGTATTTGAGTAAAAGAGAAAAAATGATTAGGAATCACTTTACTTAAATATTTTTACTGCTATAGGAAGACAGATGGCTTTCTTAACATATGAATCAAAAATTGGGGTGTTTTGATAAACTTCAAGTAATTTAAGAAAAGCCTAGTGAGTGATGTTGAATCACTTTTACCAACTGATAAAATATTTGAACTATCATTTTCACAATAACCATTAGTTGAATGATTCATATAATTGATATAAGCAGTGTTTCACAAGTACTTGAAACAAGTAAATCCTATAAAAATTCAACATATAAATAACTGGAAAGTAAAAAATGAGTTTTTAACAAGTAGGATAATTATTTTCTTGGATGTCAGTAACGAGAAAAATATGTGGAAATGAAGCAAAAATGCAATCTTCTAAGACTTTCCTTAGCTGTCAAAACCTAGGGAGGGCCAGGCACGGTGGCTCACGCCTGTAATCTCAGTGCATTATTTGAGTCCAGGAGTTCAAGACTAGCACCTGGGCAACATGGCAAAACCCCATCTCTATTAAAAATACAAAAATTAGCCAGGCATGGTGGTGCGCACCCGTAATCTCAGCTACAGTGCACACCTGTAATCTTGGCTACTTGGGTGGCTGAAGCATAAGAATCACTTGAACCCGGGAAGCAGAGGTTGCAGTGAGCCGAGATTGCGCCACTGCACTCCAGCCTGGGAGACAGAGCGAGACTCTGTCTCTAAAAAAAAAAAAAAAAAAACTGAGGGAGAACTTTACTGGTAAGAAGTTGTCTTCCACTCCTAAAGAGGAAATCACTTTTTTTTTTTTTTTTTTTAAGAGACAGGGTCTCACCGTGTTGCCCAGACTAGCCTTGAAGTCCTGGGCTCAAGCAATCCTCCAGCCTCAGCCTCCCCAGTAGCTAGGATTACAGGTGTGCACCACCACATTCATCTGGAAATCGCATTTCTGATTGTATTATTCTTTCTAAAGAGGGGCTTGCTTATAAGCTTTCCTTCTACGTTATAATGTGAGGACACATTGGGACACAAGCGTACAAAGTACAATTCATTCATTATTCAACACATATTTATCGAATTCTCACAAGGTGCCAGACAGTTGCCATTCTCCAATTAGGAATAGGTTAGTGAGCAGGACACAGTTCCTGTGCTGCCAGGAGGGAGAGAGAGACGATAAGAAACACACCTGGCTCACACCTGTAAGCCCTGCACTTTGAGAGGCTGAGGCAGAGGAGGATCTCTTGAGGCCAGGAGTTGTAGACCAGCCTGGGCAACAAAGGGAGACCCCATCTCTACAAAAATACAAAAATTAGCCAGTTGTGATGATGTGTACCTATAGTCCCAGCTTCTTGAGAGGCTGAGATGGGAGGATTACTTGAGCCCAGGAATTTGAGGCTATATTGAGCTATGATTGTGCCATTGCACTCCAACCTGGGTGACAGAGCAAGACCCTGTCTCTAGGAAAGAAAAGAAAAGAAACATTCCAGATAATGAGAAGTGCTATGGAGAGAATTAAAATAGGATGATGTGGTAGAGACGCCTGCCTGGCCACTTCAGGCTGGGTGGTCAGGGAATGCCCTTTGAAGAGGTGAGAGTAAGACAAGACCGGAATGACAGGAAGGACGCAGCTGTGCAGAGACCTGGGGAGAGGAGAGACTTCAAGGCAGAAGGAACAGCTCAGCGATAGTGCGCTAAATCTTTCCTTGCTTTAATTTGAATGCACTGACAAATCCTCCTCTTCCTTTGGGGCTCCAGCGAAAGGTTTTTAAGTGTAATTTTATGACTGATATTCCCAGAGAGTGAACTGACAGGCTAGGAGTGACGATAAAAGCGGGTGTGTGGAAGAAAACAGGGCAGAGACCAGGATGAGGCAAATGAGATGCTTCAGGCACAAAATGTAAGGCCATGCAGTGCAAATGACTCACAGAGTTCTGCCTCCCTGCATTTTGCACCCTAAGCACTTCGCTAGCCTCACTCTTGTCACAGCCCTGGGAAGAAGGGAGAAGTAGAGTTGTGAGATATGCTGGTGCTTTGAAGATCCAGCAGGTTTGGGTGTAGAGGGGGAGATAAAATGGAAAACATTAAAACAGCCTAGGAGGAGGACCGCCCCCCCCCCCCCCCATATACATACTTCCAGCCCCAGGACCCGGATCCCACACAGCAGCCCTCCGCCTGGGGGCACCCTTCACAGCTTCTCAGGATGATAGACTGTCATGCCCCACGAGTCTGGGTACGTTTCTTTAGCTTCTTGAGTTCATAACTGGACTGGCAGTGTGAGAAGCACACAAGGCCACCCTGTGTGGCACCTGTGACAGCAGGCATGCCAGATTGCCTGCCATTGGTTAAGGAGACAGCTGCCAAGACCTGAAGGGACACCACTGCTTATCGAGGGTATCTTTCTATAAGGATTCTACTGCTACCATCTTTTACAGATAGGTGTCAAGTAAAAGTTGTCTGTGTTGGGAAATTCCCAGAAAGGTGATCTGTTGGGTGAGTTCCTCCCTGGCCTCCTACAGAGCCAGCTAAGGACAAGCTGAAGGATAATGGCAGCATGGCAGGAACAGGCGATCTGAATTAGGTGACAGGGAATGATTTTCAGCCTCAGCGTTGCAGTATTGTGTGCCTGAATCAAAATACCACCACTCCCTATTTTTTGTGTGCTAAATTTTAAAGGATTATTACATTACCACACTGTGGAATCTCTTTTGTTTGTTATCCTTTAAAAAAATGCTGTTTTCTTTTTTTCTTTTTAAAAG
Seq C2 exon
AATATGGATTGTGCTCAGTTCCGTTTGAAAATAAGCTCTATCTAGTCGGCGGACAAACTACAATCACAGAATGCTATGACCCTGAACAAAATGAATGGAGAGAGATAGCTCCCATGATGGAAAGGAGGATGGAGTGCGGTGCCGTCATCATGAATGGATGTATTTATGTCACTGGAGGATACTCCTACTCAAAGGGAACGTATCTTCAGAGCATTGAGAAATATGATCCAGATCTTAATAAGTGGGAAATAGTGGGTAATCTTCCCAGTGCCATGCGGTCTCATGGGTGTGTTTGTGTGTATAATGTCTAATTGAATCTGCAGAAATGACCAAGCAATCACTTTTTTGGAGTATAGTTTTATAAAAAAAGAATGCAGGGTTTGAAGTTCCTTACCTGATAATTGTGTCTGGCACATGATAGGGGATCAGTAAATTGTAATTCCTAACCCTACTGTACTCCCAAACATGGTGATTCATGGTCAAGAAAAATCTTATATATATATATAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000213160-KLHL23:NM_144711:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.020 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0134420=Kelch_1=WD(100=90.4)
A:
NA
C2:
PF0134420=Kelch_1=WD(100=37.5),PF0134420=Kelch_1=WD(100=46.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)