HsaINT0101779 @ hg38
Intron Retention
Gene
ENSG00000145794 | MEGF10
Description
multiple EGF like domains 10 [Source:HGNC Symbol;Acc:HGNC:29634]
Coordinates
chr5:127445457-127447684:+
Coord C1 exon
chr5:127445457-127445693
Coord A exon
chr5:127445694-127447556
Coord C2 exon
chr5:127447557-127447684
Length
1863 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
3' ss Seq
ATTTCCTTCCCTTCTTGCAGGAA
3' ss Score
12.77
Exon sequences
Seq C1 exon
CTGGTGTTATCATAGTTGGAAATCTGAACAGCTTAAGCCGAACCAGTACTGCTCTCCCTGCTGATTCCTACCAGATCGGGGCCATTGCAGGCATCATCATTCTTGTCCTAGTTGTTCTCTTCCTACTGGCATTGTTCATTATTTATAGACACAAGCAGAAGGGAAAGGAATCAAGCATGCCAGCAGTTACCTACACCCCTGCTATGAGGGTCGTCAATGCAGATTATACCATTTCAG
Seq A exon
GTAAGAGCAGAGGCAGGAGAGGCATTTTGCTTCTTGAAAAGTTAAATTTCATTCGGGTTCTTTAAAACTGGGTGTTTGGCTGTGCTGTCCATTGTTTCTGTCAATTCTCATTGAGAGAATTCTATGTTTGGAAAAGGTATACATTGCTAGAGATGAGTTTTTTATTTCAACAATAGTAAATTGTCATTCTGTGGTTTGCTATAAGGGTTTTAAAATTGAGCTCATTGTGTTTGTGGTTTAGATTTAGGGAATTTCAATCCATAAGGAGCTTTGTATCCAGCCTCAAGCTTTTGTCATATGTGAGGGGGGTGAGGAGGAAGAGAGGATGATAAGTTTACCAAGGTCATGGATCAGATTAGGGACCAGTTCTCCTGTCTCTGAATGAGGGTACTTTCTATGTGCTTCCCAGCCTCTCCCTAGGCCTACCCGAATCGTTAACTGAAGGGAACAAAGTTATATCAGAAACAGCTTTTTGGTATTAGCAAGAACCAAGGCAGCCCTTTAAGAAAACTCTTGATTTTTTCTGTTCTGTCACAATGCCTCATAAAAGGAAAAATAAAATTATAATCAATCATCAGTAGAAGCAACCATTTACATGGAGGAATTTAAAAGTTTAAAATCTTTATTACTTTTTGGGTGATTATTGAAGGCCTTCTGGTTGGTTACATGTTTAAAACTACAAAATTCCGTGGAAATATGAGAAGTAGCTGATTTACATAGTAGTGCATTTTCAGTGCAGAATTATTGTGTCAAGAACTCAAGTGTTTAAAAAAAGGAAAGTTGCAGAGTAGCTTCAAATGATACCTTCCCAGCTGTACCAGCCCCAAAGCAAAGAGCAGTTATCTGTGGATACTGTGAACAAAAGTTCTCTGAAAAGGAATTTGGGGGAAAGAGATTTTATTCCAGTGAACGGTTTGCAAACCCAGGAGTTGCAGCCAGTGTAAAATGAAAGTGCAGTTCAGAGAACAAAGGGAAGGCTTGGGTTTTATAGCAAAAGTCCCCACCCAGCTTCCAATCAGGCCCTTTTAGGAAAGTGAAGGATTGAAACTGGTTTAATTCTAATTGATCAGTGCAGCTGAGTTCTGGTTGGTTGACACAGCGGAACCCTGATCCTTTGATAAAGCTAAGCCCTGATTAGCTAAGGCAGGTAAGCTCTGATTGGTTGGTTCAGCTGAGCTCTGAAAGACCCAAAGATAAAAAGCTGGGTTTTCAGGGAACTCAGAGTACAGGTGTGATCCTTAGTCAGCAAAGGCCTGCTTGACTCGATTTTAAATTTAGGCCTAGGCAGCCACTCCTATGGATCTTAAATAATTGGTTCTTTCAGTTTCACATTTGTTCACAAGCTTTCATACTTTTCCAAGGAGGCAGTTAGGAAGGTAGAGGCCTGTTGCTTCTAGAAGCTTTGCTGAGTAGGCTGGGCAGGAGGAGATTCTGCCCAGCTTGTGATATGGAAGGAGTCCGGACATTTGTTCAGTTATTTATTTATTTGTTTTTTTATTTAGAGATGGAGTCTCGCTCTGTCACCAGACTGGAGTGCAGTGGTGCGATCTCGGCTCACTGTAACCTCTACCTCCGGGGTTCAAGCGATTCTTCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCATGCTACCGTGCCCGGCTAATTTTTTTTGTACTTTTAGTAGAGATGGGGTTTTACTGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTCATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCTCGCTGGGCCTGTTTTGTTATTTTGATTCCCTTTTTTCACACACATTTATGGGAGCCTGCTGCCTTAACCATTTCCTTCCCTTCTTGCAG
Seq C2 exon
GAACCCTTCCTCACAGCAATGGTGGAAACGCTAATAGCCACTACTTCACCAATCCCAGTTACCACACGCTCACCCAGTGTGCCACATCCCCTCACGTCAACAACAGGGACAGGATGACTGTCACGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145794:ENST00000274473:21
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.013 A=NA C2=0.349
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(18.9=8.8)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTGGAAATCTGAACAGCTTAAGCC
R:
CAGTCATCCTGTCCCTGTTGT
Band lengths:
343-2206
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development