HsaINT0101811 @ hg19
Intron Retention
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF-like-domains 11 [Source:HGNC Symbol;Acc:29635]
Coordinates
chr15:66257246-66263027:-
Coord C1 exon
chr15:66262891-66263027
Coord A exon
chr15:66257459-66262890
Coord C2 exon
chr15:66257246-66257458
Length
5432 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
3' ss Seq
CCCACTCTGCTCTCCCACAGGTG
3' ss Score
12.32
Exon sequences
Seq C1 exon
GGAGCAGTGTGTGCCCAGCCCTGCCCACCAGGGACATTTGGCCAGAACTGCAGCCAGGATTGTCCTTGCCACCATGGAGGGCAGTGTGACCACGTGACTGGACAGTGCCACTGTACAGCTGGATACATGGGGGACAG
Seq A exon
GTAAGGATAGTGTTAACTGTTATCTTTGCTGTCCATTTTACTCATATTCATAGGAGACTTGCAGAGAACAGCTCATAGCCCTCTCTCTGCCAGCCTTCCAGTTCCTTTCTCAGAAAGCACTCTGAGCTCTCCTGCCAGGGAGGGTTGGCACCTGATCCCTCCTCACCCTCGGCCTGCAGAGACACCCTCTTCTCTAGCCTAGTGGCCCAAGCCCTGAATTTAAATGGGCTCACCTGGGGGAAGGAGGTGAGCACCTGCCCCCACTCTCTACTCTCTGCACTCATAGAGGGAGGCAATGGCACAGATAATCCAAGGAAGCTGAGAGTACAAAATCACTTCATTCATATGTTTTGCACGATTTCTTCTGGAAGGGCATTTTTAGTCCTAATTTGGGTTCCACCAAAAGGATACTGGCATCAGTTTGCATCCTCTGAAGGCTTGTGGCTTAAGAGCAGACTGAAGGACGGTGCCAATGTCCTGGAATGAAACCAGCCTTGCAGAGTGGATAATCAAAAAAACACAGAACTGGGGAATTGCCATGTGTGCACATGTGCCACAGCGGGAAGAAGGAGGCCATGATGACAGGGCAGGTGCAGAGGAAAAGGGAGAAACAGCAACCGGTGTGTGTGATGGTGAGTAGATTGGAAGCTGGAAAAAGATATTTGAAACCCACAGAACCCAGGCCAAGTCTCCTCCCTCTCACTCTTGACCACATGGATCTCTTCAAGCAGAGAAGGGCCGTACAGAGGCAGCCCCCACACCCCATGCCTGGTTCTGTGGGGATCCATGTTTCATTTCTGGCTCTTGGACTTTATACTCTTCTCAGACAAAATGAGGAAACATTTTTCATCATTCCATGCCTGGGTGACATCAGAAAGCCGGGATGTAGGCTGAGTTAACCAATGAATCCCTCCATTTCTAATAGACATAATCGGGGCTCCTCCAGCTCCCACTAGAATCAGCCCCAAATCCTTAGTGATGTCCAGAAAAGAGATTGTCCATTAGCCTTGGGCTTATTTACCTCCAGCTGGAAGTCTTTTAAGCCAGATCTGATCTCTTTGTGAGCCAGTGTTCATCAACACTGTTCCCCAGCATAGAACGTGGGGTGTGGCATCTGGGGATCCATCCCTCCCTGACCCATGGGAGAGAGGGCTGAAACATTGAGTGCATGTTCCCATCCTCACCATCTCCCCAAATAAGGAAATGCTCAGGATGAGCCAGTACGGACTGGAATCAGGAAGATCCTCAAGCCAGCACAGGACTCCTTTTTCAGTCCACTTTCTCATGAGAGTGCAAACCGCCCGCTTGTTGTTGGAAATGAGCAGGCCCAGGGCTCTAGCCGGCTGGACTCCATACCAGTAGACCCTAGCTCATTGGTGCTGTCGATTTTCCCTGTCGAGATGTGCCAAATAGAGAAAGAATCCAAAATCTCTCTGCTTGTTGGAGCCTGGTCCATGATCCTGGGCAGAGAGGAACCCCTAAAGCCAAGGGGCCCTCCAGCAAGCTTTGCCAATCAACCACAGGAGGGTTCAATAGGAGGCCAGGCAGCATTTGGGCTTCTCACCTAAACGGGCTGCCTGGTGTTTAATATTTTGTAAAATTGCCTCCATTAATTTCGTAGGTGACAGCTGCATTAACCCACCCCAAATCATCATGAGCATATTAAAGTTGAGTGGGTGTAATAATGCAGGCCTCCCCGGATAGGCAGAAACCAGTGCAAATTAAACACGAAATGTAACGAGGGCTTTGCAGCTCATTTTGTAATTTAATTGAGCAATGTATCTGGTTGTTAATGGCAATATTGGACACATTAGATTGATATGGTGCAAAGGAAGGATGTTTAAGTAGAAAACTAATTCCTGCTGTGATTATCCTTCTGTTCCGCAGGCCCCATTATTAGCATGCTTTGTGTAAAATTCATTAGCCATCGTTGCTTGATCTCTAAATAAATAAGTTGTTTAAATTGTGAGTAGGGAAAAAAAAAAGAGGCTGATTAAGTAAATGAATTAGGTTGTCAATATTTCATTTCCAGATTGTTTTTCTGGGGCTGTAGATCCAGGCACCCCAAAAATATAGTGGGCTAGGGAATTGCCCTTCAGAGGAGTTTAGGGTTCAGGGCTCTGTCCAGTCCTGCTAAGCAGGAGGGAGCAGGAATGTTTGAAAAGGAACAGGTATCAGGAGGTATCTGGTTTGAGTTTTTCACCCGACATTTGAGACATTCGAGGCCAGCAAAGCACAGTGACTTCTGGAGAAATCCATTTGCAGGCTGAACAGGGGCTGGCAACTCAGATAGTGATTATTTGGGTCTTCAGCTGCTCTTTTTCCTCCCCTTCTGCCTCAGTTTCCCTCCTTCCCTTCCCCCATTCTACTTCTCCTCCTTCTGTCTTCTACTTTCCATTCCTTCTCCAGACATCACCTTCTTTCTTGCCTCCTCTTCCCTCTCTTTTCTGCTCTCTTTCCCTTCATGAGGCCTCAGATTGGCTGAAATATGACAAGATTTGCAGAAAGACAATCTGGGGTCATCTTAGCCACATGCAGGCTGCGTGAGCTTGGAGCAGTTGCCTCACTTGTCTCATGGCAGCCTCCTTAACTCTAAAGTGAGGGTGATGAGAATATGTGCTGCTCCAGGGGCTGGGGACAGGCTCTGGGGCCTGAGCAGCTGGAAGCCCCTCAGTATACGGTGCCCGGGGGTGTTGTCATCATGATCCCTGCTGCCCCACTATTCTGCCAGATCACTCCTTTGCTACAGTGGCTCTGAGAGGGGAGAGCTAGTGGCATCTTCTTGGGAAGGAAGCACTCAAGGCCAGACCCCAGTCACCGTCCTCTTCTCCTTGTCACTGTGGGCACAGAGCAGCAAAGGCACAGAACAGAGACAAGGACACCCCAGTCTCAAGTTGCCAAGGCTGGTGCCCCACACACTGGCTGCTCTCATCCCCCACACACTTGCTAGCTGGCCCTGCCACATCCACGAGGGTCTGACCACTCACCCTCACCATAGACAACTGAGTCATCCAGACACAGAATCTCCCTGCCCTGTCTGTAGAAGAATACTTCCACCCCCACGATCCTCCAAAATACATAATAAAGAAGTTAGAGCTGTATTTTTTTTTAAATTGCTTTTCCCCTCTGATTACTGTAGAAGATATACAGAAAGCCTGGAAAATGGAAACATATGATAATTAAAACACTAACTCCTTAAATCCACTCTACTATTAACATTTTAGAATTTTTCCCTTTGGGCTTTTTCATGCCTGAATTTAAGGCCAGAAGGTCAGATGGGCTCTGTTATAAGAACTGTTGAAAACAATATTAACATGAGTACTAGTGAAAATAACTAACTTTTCTAATTGAGCCCCAATTATGGTCTGGGCGCCTTTCTAAATGTTTACACGCATTATCCCATTTAATTCTTACAGAACCCGATGAGGTTTAGTGAGTATCGTCCCATTTTATGAAAAAGAAGAGGATGTCAGAGCTTTAGGTTAGTTCTCCATTATCCGCACTGTTGAATCAGTGCTGGAACAAAGATATCCCAGAACCCCAGAGGCTAGAGGCCATTTCCATTTGTCTTTGGGATGCCAGAAGTCATCCCCCTCTTTTACCCCTATTCCTCCAGGTTTAACCCTTGACTTATCCGGATCTAGTTGCTGTGACAATAAGTCTGCATCCTCTGGGAAAGAGCCCAGGGTGGGGGTAAGGGGTGTTGAGGCACATTCAGGAAACCAGGTGGTCAGCAGTGGGGGGTCACACTCGCCCACGGAGGAGCCACACCCATGGCTGTGGGTTAAATGAAGTTGAATAATTATCCTTATGTTGGGATCTCCAAGTACTAGCCCAGACACACACAGGACACAAAGGTGGTCCCAGGCTTCCTCCTTAGGGGCTCACAGGCTGATGGGAGAGACTCAGACCCTACCTTGAGGGGACCTTCTTCCAAGGAAGGGAAAATAGCCTTGTCACAGGGCATTCTATAGTCCAATGCAGGAAGACGCTTCCTCTACTCGAGGGAAAATCCGCAGTCAGGGAGGAGATATGTCTCCCAGTAGGACAAGAGAGACTGTACATCTGGCCCAAAGGCTCAAAAACCAGAGATACTGTATAGAAACAAAATCACCCCATTTCATCAAACCTAAGGTGCCACTGATCGTAAGATGCATCACTGTTTCATATGCTGCAAAGAATGAAAAACACTGGCAATTAAACTATGACATGTCACCAATTACAAGACTTATCTAATTTCAGAGATATAAAAATATCTTTTAAAAACAAGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGACCGAGGCAGGCGGATCATGAGGTCAAGAGATTGAGACCATCCTGGACAACATGGTGAAACCCCGTCTCTAGTAAAAATACAAAAATTAGTTGGGCGTGGCAGTGCACCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATAGCTTGAACCTGGGAGGCGGAGGTTGCAGCAAGATCATGCCATTCCAGCCTGGGCAACAGAGTGAGACTCCATCTCAAACAAACAAAAAAAGCAAGGTGTTTTTAAACCTACCTAAACAGTTTTTTGTTTAATGGGTGCAGAGTTTCAGTTTGGGAAGACGGAAACATTCTGGAGATGGGTGGTGGTGATGTGGCACAACAGTGCGAATGTGCTTAATGCCACTGAACTGTACGTGGTTAAAACAGTCAATTCTATGGGGTGTACTGTCTTAGTCTGCTCATGCTGCTATAACAAAATACCCAAGACTGAGTAATTTATAAACAATGGACATTGATTCTCACAGTTCTGGAGGCTGAGAAGTTCAAGATCAAGGGGCCGACAGGTTTGGTGTCTGATGAGGGCCCCAATCTCTGCTTCCAAAATGGTGCCTTGAAGCCTGCATCCTCAGAGGGCGAAAAGAATAGAAGAGCCAAAAAAAAAAAAAAGAAAAAAAAAAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGGGACCTCACTGGCTCCCTCCAGCCCCTTTTATGAAAGCACTAATCCATTCATACCCTAATCACCTCCCAAAGGCCACACCTCCTAATACCATTGCATTGGGTGTTAAGTTTCAATGAGAATTTTGAGAGAAACATTTAAACCATAACCTGTATATTTCACCACAACTTTAATTTTTAAAAATTATTAGGCTTGGAATCAATAAAATATGGTGGTACAAACTCATTGCTGGGGGGACTGAGCCGACCTGGCATGAAAGGCAGAAATGACTGGGGCGAACTAAACCATGGACTACTTCCTGGAGGAGGAGAGAGAAAAGGGGAGGAGGCTGTGAGCAGCGTGGAGCACACCAGGCCTGGGCCAGATGGCCAGGAGGACCACATCCTGGAGGATCTTGAAGCACAGGTGAGGGATCCTGGCCCACAGCCTCAGCCCCACTCTGCTCTCCCACAG
Seq C2 exon
GTGCCAAGAGGAGTGCCCCTTCGGGTCCTTCGGCTTCCAGTGCTCACAGCACTGTGACTGCCACAATGGGGGGCAGTGTTCACCCACCACGGGTGCCTGCGAGTGTGAGCCTGGCTACAAGGGCCCACGCTGCCAGGAGCGACTGTGCCCGGAGGGCCTGCATGGCCCAGGCTGCACCCTGCCCTGCCCCTGTGACGCTGACAACACCATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-MEGF11:NM_032445:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF126612=hEGF=PD(23.1=6.5),PF0005319=Laminin_EGF=PU(55.3=56.5)
A:
NA
C2:
PF0005319=Laminin_EGF=PD(42.6=27.8),PF126612=hEGF=WD(100=18.1),PF0005319=Laminin_EGF=PU(20.4=13.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)