RnoINT0091351 @ rn6
Intron Retention
Gene
ENSRNOG00000010634 | Megf11
Description
multiple EGF-like-domains 11 [Source:RGD Symbol;Acc:1582797]
Coordinates
chr8:70123174-70129690:+
Coord C1 exon
chr8:70123174-70123310
Coord A exon
chr8:70123311-70129477
Coord C2 exon
chr8:70129478-70129690
Length
6167 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
3' ss Seq
CCTGCTCTGCTCTCCCACAGGTG
3' ss Score
13.11
Exon sequences
Seq C1 exon
GGAGCAGTGTGTGCCCAGCCCTGCCCACCAGGGACCTTTGGCCAGAACTGTAGTCAGGACTGTCCCTGCCACCATGGAGGCCAGTGTGACCATGTGACTGGACAATGCCACTGTACAGCTGGATACATGGGGGACAG
Seq A exon
GTAAGGTGGCATTAACTCTTGCCTGTGGTGTTCAGTTGTTCATACTCTTAGCAGCCTTGCGGAGGGTACCCTGCCTGGCCAGCCTTCTGGTTCTTTCCTCAGAAGGCATTCTGAATCCTACCAAGGAAATCCATCCATCAGCTTACCCTGTCTCTCCCGCACGCGCATGCCCTCCACCAGCCTCGCTGCCCTGGACTTTGAATGAAGCCAACCTGGCAGAGGGAACAGGCAACAGAGCACAGACCCAAGGAACTGCCTTCTGGACACAATTGGAAGACAGCCGTGGGGTCAGGGCACACTGTGGGAGAGGGAGAAGCAAGGCCCACGTATCTGGTGCCGTGCTGAACTGGAGGTGGAGGATCACACTTGCGTCCACACACCCAAGGCCAGGTCCCCTTCTCCCCCAACCATCCAGAGGAGTCCTGCCTCTTGCCTGGCACTGTGCAGGTGGATCTAAGTTTCACCTCTGGTCCCTGAATGTTACTGTTATTTTTCTAGACAAAGCGAGAGGAGATACTGTAAGAAGCACAGCTTAGACTAAGCACTGGGGAAACCAGGACTGTCAATCACAGGGCCTGTCTTCTGCAATGGAAGGAAGTGTGCCTGAACGCCTCTGTGCTTGAGTGACTCAGTCAGACAGCCTGGTGATCCTTCGCTATTCTGTTAGGAGCCAGCCTCCTCCTGAATCCCCCAACACCCTGAGCTTTGTCTCCAGTGAATGGACCACATCTCTGTCTACTTCCCATCCTCCATCAATAGACTCTATCCTTATGCTTGTCATAGATTCTCTCTCCAGGCCGTAGCCCTGAACTTGCCCATCAGCCAATAGAATTCAAGCGTACAGAAAAGGTCAAAGGTGCTTTGCTGCTTTGCAAATGGTGTAGTCAGCCCTGAAGCTTTGTTATGAGAATTGTCATGTGAAGACCTTTCCCCCAAAGTTCTACAATGTTTAAATGTGTAAGAAAAAGCCCAGGGTGTGGGCTCTGAGGACCTGGAATTAAGTGCTAGATCCACCTTCCCATCACATCTTCAAACCCCACGGTAAGGAAATGTTGGGGACCAGAGAAGCCCTCGCCCCCACCCCCACCCCACCCGTCTCCGTATTCCTGCCCTTATTCTGGTGTTGGAAACCAGTGTTAGCAGGATACCAGGCACCACCAGCAGAACCAGCTCTTTGACTCTCAGGCTTCACCAAGGGCGGAAATAATCCCGTGTCTCACCCCTGATCTCAGAGCAGAGAAAATCTCCAAATACACGGGCCTTCCAGATTGTTTTGTCAGCCGCCTCAGGAGGGTTTATGCAGAGCTCTGAGTGCATTTGGCTTTCCTGCCTCAACAGGCTGCCTGGTGTTTAATATTTTGTAAAATTGCCTCCATTAATTTTGTAGGTGACAGCTGCATTAGCCCACCCCAAATTATCATGAGCATATTAAAGCCAAGTGGGTATAATAATGCGGGTCTCCCCAGATCGGAGGGTTCCAGCTCAAATTAAACACGAAACGTAACTTGTAATTTAATTGAGCAATGTATCTGGTTGTTAATGGTGATATTGGACACATTAGATTGATATGTTGGGAAGGAAGGGTGTTTAAGTAGAAAGTTAATCCCTGCTGTGATTACCCTCCTGTTCCACAGGCCGATTATTAGTGTGCTTTGTGTAAAATTCATTAACAGTCTTTGCTTGATCTCTAAATAAATAAGTTGTTTAAACTGTGGCTAGGAAAAAAAAGTAAAAAGGGACTGATTATGCAAATGGATTAGGTTGTCAATATTTCATTTCTAGATTTTTTTATTTCTGGGCAGGTAGATTCAGTGCCCCCTCCTCTGGGGTACAGCCGGGTGGGACACTCTCTTCAGAGGAGCTGTCTCTCCTGCAGGGCAGGGATATTCCAATGCAAGTGAGCAGGTGTCTCCTGGTGTGAGTTTCTCTCCTGACACCAGAGAGCTCTGAGTCCTGCAGAACTCAGTGGTCTGTGGAGAAATCTGGAGGCTGAGCAGGGATTGACAGTTTAGACCATGGGTCTTTAGCTGCCCTTGGTCCTTTCCCTCTACCTCTGTTCCCTCCCTTCCCCTCCTCCTCTGAGCTCCCCCTTTCTCTCTCCTGCCTGCTACCCAATCTTCCTCCTCCAGCCCTTTGTTCTCTCCCCAGCAGGTTGGGGCAGCCCAGGTCGTTTTCACTGTTTGCCTTTGGCCACATTCCTTCTCTCACTCAGTGGCTCTGAGAGGACAGCCAGTGGGCATCTCCCTTGAGGGGTGCTCTAAAGCTATGCCCCAGTCACTCCGCTGCTCTCCTGTCACTCTCTTGCTCTCCTGTCACTCAGTGTATGGAACAGTGAAGTCAGAAACAAGATCACCTGGTCTCTAGTTGCCAAGGCTAGTCCTGAATATTCTGGCTGCTCCCAATTTCCCCATACACAATGCTGCCCACCCCCAGGTCCACTGGAGTGTGGCTGTGTGTCCTCATTTAGGCCACTGGCCTCTCACCAAGACCAGGCTGTCCCTGCTCTGTCTGAAGAAGAATGAGCCTCCAAGAAGTTATGGGTATGGTCTTAATTAGGGTTCCTATTGCTGTGATACAACACCACGACCAAAAGCAACTTGGAGAGGAAAGGGTTTATTTTGCTCGTTTTCACATAATACTTCATCATTAAAAGCAGTGAGCGCTGGAAATCAAGCAGAGCAGGAAGGGAGGCAGGAGCTACCACGAAGACCTTGGAGGGACGCTGCTCTCTGGCTTGTTCTTCATGGCTTGCAGAGCCTGCTTTCTTCTAGAACCAAGACTGCTAACCCAGGGGTGGCCCTATCCACAATGGGCTGGATCCTCCACATCAACCACTAATTAAGAAAATGCCCTTCAGGCTTGCCTACAGTCCGACTTTATAGAGGCATTTTCTCCATTGAGGCTCCCTCCTCTCCATTGATTCTAGCTTGTGTCAAGTTGACATAAAACTAGCCAGCACAGGGTACATTTAGAATATAAGCAAATGAGGATGTAGCTCAGTAGAGTGCTTGCCTAGCATGCATAAAGATCCGAGGTTGCACAAACCCCTCTTCACTTGAAATGCCAGGCGTGTTCCTTCCGTACCCCCAGTACCGAGTAAATAGGCTTTGATGGTTCATGCCTGTGATGCCAGCACTCAGGAGGTAGAAGTAAGAGGATCAGGAGTTCACGGTCACGCTTGAATACAAAGCATAAATCCGAGGTGGAGGGGTGAGCGAGATGACTCAGCACATGAGTGTGCCTGCCACTGGAAGCCTGAGTTCCATCCCTGCAACACCTGTAAAAGTGGAAGGGCAAAGCCATCTCCTCAGCCCACCCTCTGACCCCCACACAAGTGATAATGAAACTGCATCTAATTCCTCAAGTTCATGCTTCCATTGCATTTCTGAATTCTTTTCTTTGAGCCTTCTCATGCCTGAAACTAAGTCAAGAGGGTCATTCATGTCTGCTGTGTTTTAAGAACTGAGATCAGCAGTTTAGAAATTTATTTAAGAGTAGCAACGAATAACCATCTCCTGGCTACCTTTCTGGATGGTACTACACCTTTTTAAAATTGCGTGCATGGTAATGAGTTGCTGGCATTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACGCACATGCTACTTTATTGGATTCTTATATCTACCCTTCCAACCCAAATTCCACCCTAATCTCTTCCCATCCCCCACACTTAGAAATTTATTTAAGAGTAGCAACGAATAACCATCTCCTGGCTACCTTTCTGGATGGTACTACACCTTTTTAAAATTGCGTGCATGGTAATGAGTTGCTGGCATTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACGCACATGCTACTTTATTGGATTCTTATATCTACCCTTCCAACCCAAATTCCACCCTAATCTCTTCCCATCCCCCACACTAGGTCGGAGAGAAAGAAGTTTAGAGTCCGCCTCTTTAGATACTTCCTGCAAATTACAGCCACTGGGCGCCTTGGGGCAAGTCTAATCTTCCTCATCAGGATATGTCCGACTTCTCTTTGCTTACAACTACTTGACAAACCACAACAGGAACCAGCATCAGGGGGAACAGCAGCCTCCCCAGGCCCTCTCAGGGCTCTTACAGAGTCCCCAGAATTAACCTGTCTGCAGTGGGCAAAGATCAACAACCCCCTCCCCCCCAGTGCACTAGACAAATCATAATCACCGGCTGTGAAGCAGCCTCTTCTCAGCCCCTGGGATTAAAACAAAAACACATAATATAACTGGGTTCTTAAAGAAACTAAAACTCTAACTACAAAGGACCATGCACATTCGAGTGCAGTGCCAGGGGAGACTACATATGGGGGTGGGGGTGGGGTGGGGGAGCGCTGTACCTGCAGACACAGGTGGTTGTGAGCTGTCCAGTGCAGGTGCTGGGAACAGAACTCAGATCCTGCAAGTCAAGTTCAAGCTCTTCACTGCTAAAGCCTTCTCTCCAGCCCCCGGTGTTGTTTTATTTAATCTTCAAACAACCTGATGAGGGTTTCCAGCTCATTTTATGAGGAGGACGTGGTTCATCAGAAGTTTAAGTCTGATCTTTGTTTTTTATATCATTAAAGCAGAGTTAAGAACTTGATAATCCCTAACCCCATAGGCTATTTCTCTCCAGTGCACAGGTTGCCCCCCAAGGTAACCCTTTATTGCCTCAAGGTCCAGTTGCTGTGACAATGAGCTTGTGCCCCCTGAGGAATTACCCTGGGCTGCAGCAAGGGAGGTTAAAGGAGATTCAGGAAGCCAGCAGCAACAGCCAAAAGCCCCTCATCTACTGGCCTTTAAGCTAATGAAATAGAGAATACAGGGACCCCCGAGGACCTGTATGAGTTCACATAGCACCAAGTGTCAGCCCTCCACCTTGCGAGCTCACTGACTGATGGGAGAGAGGACTCCTGCCTTAAGGATCCTCAGATCTCAGAATAGCAAATAGCCGGTCTCTGGGAGTATGCAAACTGACGAAGGAGGAAGACACGTCTACCTGAGGAAAGTTCCAACCTCAGAGAATGAGTCCTATGGCTCCACATGACAGGGGAGAGAGGCTTCTGCCTGAGACTCAGGAGAGCACATGTGAGTAAGCCCAGCAGTCAGGAGTTTGGGCTGTAGGATTGCTGTGAATTTGAGGCCAGCCCAGCTTACATAGTGAATTCTAGGACACCAAGCTGAGCTACAGAGTAAGGCTCTGTCTCAAACAAACAAACAAACAAACAAACAAACAAACAAACAAACAAAAATTCCCAGCACCACTTAAACCAGGCATGGTAGCTCTCAGGAGGTGGAAAGGAAAGATGGGAAGTTCAAGGTCACCCTTGGCTATGCAGTGAATTTGAAGCCCAGCCTGGTCTATATGCAACTCTTTAAATATAAATAAATTGGTTAGGAGCTGGAGAGATGGCTCAGTGGTTAAGAGCACTCACTGCTCTTCCAGAGGTCCTGAGTTCAAATCCCAGCAACCACATGGTGACTCACAACCATCTGTAATGGGATCTGATGTCCTCTTCTGGTGTGTCTGAAGAGAGTTACAATGTACTTATTTATATATAATTTATATATATAATATATATATTATATATAATATATATTATTTATATATAATATATATATTATTTATATATAATAAATAAATCTTAAAAATAAATTAGTTAATTATACAATTAATTATAACAAAAACTTTCATCATGAAGTTTGAAAGAAACATTCAAGCATTTAAACCACAGCACACACATTTTATCACACTTTTTTTTAAAAAGAGGACTTCAGTTACTACACATGGCTGGTAATCACACAGGGCCACCAGGCTGGCCCCAAACCTAAAGGACATCCTGTCTCAGCCTCACTAGTGGCTAGGATTACAGGCATAAGCCACTGCATTCAGTCTTATCCTAGCTTTTTATAATGACACAGAAACAAAGTTTCACGTCCTGACAAGGATAATAGGAGCTCATCTTAGCTGCCGAGAAGACCTGGGGTGAAGTTCCCACGGGTATGGAGGAGGAGGCTGGGAGGGAGCGAACAGGCCAGGCATTCCAAGGGAGGAGGAGTCTATGCAAATAAGCAAGAAGCCCAGCAAGGGCTCCGCCCACAGCTCCATCCTGCTCTGCTCTCCCACAG
Seq C2 exon
GTGCCAAGAAGAATGTCCCTTTGGAACTTTCGGTTTCCGGTGCTCTCAGCGCTGTGACTGCCACAATGGAGGTCAATGTTCACCAGCCACAGGTGCCTGTGAGTGTGAACCTGGCTACAAGGGCCCTAGCTGCCAGGAACGGCTATGCCCCGAGGGCCTGCATGGCCCAGGCTGCACCTCGCCCTGTCCCTGTGACACTGAGAACACTATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000010634:ENSRNOT00000037941:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.097 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF126612=hEGF=PD(23.1=6.5),PF0005319=Laminin_EGF=PU(55.3=56.5)
A:
NA
C2:
PF079748=EGF_2=PD(3.2=1.4),PF079748=EGF_2=WD(100=43.1),PF0005319=Laminin_EGF=PU(18.8=12.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]