HsaINT0101811 @ hg38
Intron Retention
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65964908-65970689:-
Coord C1 exon
chr15:65970553-65970689
Coord A exon
chr15:65965121-65970552
Coord C2 exon
chr15:65964908-65965120
Length
5432 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
3' ss Seq
CCCACTCTGCTCTCCCACAGGTG
3' ss Score
12.32
Exon sequences
Seq C1 exon
GGAGCAGTGTGTGCCCAGCCCTGCCCACCAGGGACATTTGGCCAGAACTGCAGCCAGGATTGTCCTTGCCACCATGGAGGGCAGTGTGACCACGTGACTGGACAGTGCCACTGTACAGCTGGATACATGGGGGACAG
Seq A exon
GTAAGGATAGTGTTAACTGTTATCTTTGCTGTCCATTTTACTCATATTCATAGGAGACTTGCAGAGAACAGCTCATAGCCCTCTCTCTGCCAGCCTTCCAGTTCCTTTCTCAGAAAGCACTCTGAGCTCTCCTGCCAGGGAGGGTTGGCACCTGATCCCTCCTCACCCTCGGCCTGCAGAGACACCCTCTTCTCTAGCCTAGTGGCCCAAGCCCTGAATTTAAATGGGCTCACCTGGGGGAAGGAGGTGAGCACCTGCCCCCACTCTCTACTCTCTGCACTCATAGAGGGAGGCAATGGCACAGATAATCCAAGGAAGCTGAGAGTACAAAATCACTTCATTCATATGTTTTGCACGATTTCTTCTGGAAGGGCATTTTTAGTCCTAATTTGGGTTCCACCAAAAGGATACTGGCATCAGTTTGCATCCTCTGAAGGCTTGTGGCTTAAGAGCAGACTGAAGGACGGTGCCAATGTCCTGGAATGAAACCAGCCTTGCAGAGTGGATAATCAAAAAAACACAGAACTGGGGAATTGCCATGTGTGCACATGTGCCACAGCGGGAAGAAGGAGGCCATGATGACAGGGCAGGTGCAGAGGAAAAGGGAGAAACAGCAACCGGTGTGTGTGATGGTGAGTAGATTGGAAGCTGGAAAAAGATATTTGAAACCCACAGAACCCAGGCCAAGTCTCCTCCCTCTCACTCTTGACCACATGGATCTCTTCAAGCAGAGAAGGGCCGTACAGAGGCAGCCCCCACACCCCATGCCTGGTTCTGTGGGGATCCATGTTTCATTTCTGGCTCTTGGACTTTATACTCTTCTCAGACAAAATGAGGAAACATTTTTCATCATTCCATGCCTGGGTGACATCAGAAAGCCGGGATGTAGGCTGAGTTAACCAATGAATCCCTCCATTTCTAATAGACATAATCGGGGCTCCTCCAGCTCCCACTAGAATCAGCCCCAAATCCTTAGTGATGTCCAGAAAAGAGATTGTCCATTAGCCTTGGGCTTATTTACCTCCAGCTGGAAGTCTTTTAAGCCAGATCTGATCTCTTTGTGAGCCAGTGTTCATCAACACTGTTCCCCAGCATAGAACGTGGGGTGTGGCATCTGGGGATCCATCCCTCCCTGACCCATGGGAGAGAGGGCTGAAACATTGAGTGCATGTTCCCATCCTCACCATCTCCCCAAATAAGGAAATGCTCAGGATGAGCCAGTACGGACTGGAATCAGGAAGATCCTCAAGCCAGCACAGGACTCCTTTTTCAGTCCACTTTCTCATGAGAGTGCAAACCGCCCGCTTGTTGTTGGAAATGAGCAGGCCCAGGGCTCTAGCCGGCTGGACTCCATACCAGTAGACCCTAGCTCATTGGTGCTGTCGATTTTCCCTGTCGAGATGTGCCAAATAGAGAAAGAATCCAAAATCTCTCTGCTTGTTGGAGCCTGGTCCATGATCCTGGGCAGAGAGGAACCCCTAAAGCCAAGGGGCCCTCCAGCAAGCTTTGCCAATCAACCACAGGAGGGTTCAATAGGAGGCCAGGCAGCATTTGGGCTTCTCACCTAAACGGGCTGCCTGGTGTTTAATATTTTGTAAAATTGCCTCCATTAATTTCGTAGGTGACAGCTGCATTAACCCACCCCAAATCATCATGAGCATATTAAAGTTGAGTGGGTGTAATAATGCAGGCCTCCCCGGATAGGCAGAAACCAGTGCAAATTAAACACGAAATGTAACGAGGGCTTTGCAGCTCATTTTGTAATTTAATTGAGCAATGTATCTGGTTGTTAATGGCAATATTGGACACATTAGATTGATATGGTGCAAAGGAAGGATGTTTAAGTAGAAAACTAATTCCTGCTGTGATTATCCTTCTGTTCCGCAGGCCCCATTATTAGCATGCTTTGTGTAAAATTCATTAGCCATCGTTGCTTGATCTCTAAATAAATAAGTTGTTTAAATTGTGAGTAGGGAAAAAAAAAAGAGGCTGATTAAGTAAATGAATTAGGTTGTCAATATTTCATTTCCAGATTGTTTTTCTGGGGCTGTAGATCCAGGCACCCCAAAAATATAGTGGGCTAGGGAATTGCCCTTCAGAGGAGTTTAGGGTTCAGGGCTCTGTCCAGTCCTGCTAAGCAGGAGGGAGCAGGAATGTTTGAAAAGGAACAGGTATCAGGAGGTATCTGGTTTGAGTTTTTCACCCGACATTTGAGACATTCGAGGCCAGCAAAGCACAGTGACTTCTGGAGAAATCCATTTGCAGGCTGAACAGGGGCTGGCAACTCAGATAGTGATTATTTGGGTCTTCAGCTGCTCTTTTTCCTCCCCTTCTGCCTCAGTTTCCCTCCTTCCCTTCCCCCATTCTACTTCTCCTCCTTCTGTCTTCTACTTTCCATTCCTTCTCCAGACATCACCTTCTTTCTTGCCTCCTCTTCCCTCTCTTTTCTGCTCTCTTTCCCTTCATGAGGCCTCAGATTGGCTGAAATATGACAAGATTTGCAGAAAGACAATCTGGGGTCATCTTAGCCACATGCAGGCTGCGTGAGCTTGGAGCAGTTGCCTCACTTGTCTCATGGCAGCCTCCTTAACTCTAAAGTGAGGGTGATGAGAATATGTGCTGCTCCAGGGGCTGGGGACAGGCTCTGGGGCCTGAGCAGCTGGAAGCCCCTCAGTATACGGTGCCCGGGGGTGTTGTCATCATGATCCCTGCTGCCCCACTATTCTGCCAGATCACTCCTTTGCTACAGTGGCTCTGAGAGGGGAGAGCTAGTGGCATCTTCTTGGGAAGGAAGCACTCAAGGCCAGACCCCAGTCACCGTCCTCTTCTCCTTGTCACTGTGGGCACAGAGCAGCAAAGGCACAGAACAGAGACAAGGACACCCCAGTCTCAAGTTGCCAAGGCTGGTGCCCCACACACTGGCTGCTCTCATCCCCCACACACTTGCTAGCTGGCCCTGCCACATCCACGAGGGTCTGACCACTCACCCTCACCATAGACAACTGAGTCATCCAGACACAGAATCTCCCTGCCCTGTCTGTAGAAGAATACTTCCACCCCCACGATCCTCCAAAATACATAATAAAGAAGTTAGAGCTGTATTTTTTTTTAAATTGCTTTTCCCCTCTGATTACTGTAGAAGATATACAGAAAGCCTGGAAAATGGAAACATATGATAATTAAAACACTAACTCCTTAAATCCACTCTACTATTAACATTTTAGAATTTTTCCCTTTGGGCTTTTTCATGCCTGAATTTAAGGCCAGAAGGTCAGATGGGCTCTGTTATAAGAACTGTTGAAAACAATATTAACATGAGTACTAGTGAAAATAACTAACTTTTCTAATTGAGCCCCAATTATGGTCTGGGCGCCTTTCTAAATGTTTACACGCATTATCCCATTTAATTCTTACAGAACCCGATGAGGTTTAGTGAGTATCGTCCCATTTTATGAAAAAGAAGAGGATGTCAGAGCTTTAGGTTAGTTCTCCATTATCCGCACTGTTGAATCAGTGCTGGAACAAAGATATCCCAGAACCCCAGAGGCTAGAGGCCATTTCCATTTGTCTTTGGGATGCCAGAAGTCATCCCCCTCTTTTACCCCTATTCCTCCAGGTTTAACCCTTGACTTATCCGGATCTAGTTGCTGTGACAATAAGTCTGCATCCTCTGGGAAAGAGCCCAGGGTGGGGGTAAGGGGTGTTGAGGCACATTCAGGAAACCAGGTGGTCAGCAGTGGGGGGTCACACTCGCCCACGGAGGAGCCACACCCATGGCTGTGGGTTAAATGAAGTTGAATAATTATCCTTATGTTGGGATCTCCAAGTACTAGCCCAGACACACACAGGACACAAAGGTGGTCCCAGGCTTCCTCCTTAGGGGCTCACAGGCTGATGGGAGAGACTCAGACCCTACCTTGAGGGGACCTTCTTCCAAGGAAGGGAAAATAGCCTTGTCACAGGGCATTCTATAGTCCAATGCAGGAAGACGCTTCCTCTACTCGAGGGAAAATCCGCAGTCAGGGAGGAGATATGTCTCCCAGTAGGACAAGAGAGACTGTACATCTGGCCCAAAGGCTCAAAAACCAGAGATACTGTATAGAAACAAAATCACCCCATTTCATCAAACCTAAGGTGCCACTGATCGTAAGATGCATCACTGTTTCATATGCTGCAAAGAATGAAAAACACTGGCAATTAAACTATGACATGTCACCAATTACAAGACTTATCTAATTTCAGAGATATAAAAATATCTTTTAAAAACAAGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGACCGAGGCAGGCGGATCATGAGGTCAAGAGATTGAGACCATCCTGGACAACATGGTGAAACCCCGTCTCTAGTAAAAATACAAAAATTAGTTGGGCGTGGCAGTGCACCCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATAGCTTGAACCTGGGAGGCGGAGGTTGCAGCAAGATCATGCCATTCCAGCCTGGGCAACAGAGTGAGACTCCATCTCAAACAAACAAAAAAAGCAAGGTGTTTTTAAACCTACCTAAACAGTTTTTTGTTTAATGGGTGCAGAGTTTCAGTTTGGGAAGACGGAAACATTCTGGAGATGGGTGGTGGTGATGTGGCACAACAGTGCGAATGTGCTTAATGCCACTGAACTGTACGTGGTTAAAACAGTCAATTCTATGGGGTGTACTGTCTTAGTCTGCTCATGCTGCTATAACAAAATACCCAAGACTGAGTAATTTATAAACAATGGACATTGATTCTCACAGTTCTGGAGGCTGAGAAGTTCAAGATCAAGGGGCCGACAGGTTTGGTGTCTGATGAGGGCCCCAATCTCTGCTTCCAAAATGGTGCCTTGAAGCCTGCATCCTCAGAGGGCGAAAAGAATAGAAGAGCCAAAAAAAAAAAAAAGAAAAAAAAAAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGGGACCTCACTGGCTCCCTCCAGCCCCTTTTATGAAAGCACTAATCCATTCATACCCTAATCACCTCCCAAAGGCCACACCTCCTAATACCATTGCATTGGGTGTTAAGTTTCAATGAGAATTTTGAGAGAAACATTTAAACCATAACCTGTATATTTCACCACAACTTTAATTTTTAAAAATTATTAGGCTTGGAATCAATAAAATATGGTGGTACAAACTCATTGCTGGGGGGACTGAGCCGACCTGGCATGAAAGGCAGAAATGACTGGGGCGAACTAAACCATGGACTACTTCCTGGAGGAGGAGAGAGAAAAGGGGAGGAGGCTGTGAGCAGCGTGGAGCACACCAGGCCTGGGCCAGATGGCCAGGAGGACCACATCCTGGAGGATCTTGAAGCACAGGTGAGGGATCCTGGCCCACAGCCTCAGCCCCACTCTGCTCTCCCACAG
Seq C2 exon
GTGCCAAGAGGAGTGCCCCTTCGGGTCCTTCGGCTTCCAGTGCTCACAGCACTGTGACTGCCACAATGGGGGGCAGTGTTCACCCACCACGGGTGCCTGCGAGTGTGAGCCTGGCTACAAGGGCCCACGCTGCCAGGAGCGACTGTGCCCGGAGGGCCTGCATGGCCCAGGCTGCACCCTGCCCTGCCCCTGTGACGCTGACAACACCATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890:ENST00000409699:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.044 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(56.8=54.3)
A:
NA
C2:
PF079748=EGF_2=PD(3.2=1.4),PF0005319=Laminin_EGF=WD(100=56.9),PF0005319=Laminin_EGF=PU(20.4=13.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development