HsaINT0105974 @ hg19
Intron Retention
Gene
ENSG00000143033 | MTF2
Description
metal response element binding transcription factor 2 [Source:HGNC Symbol;Acc:29535]
Coordinates
chr1:93576102-93580340:+
Coord C1 exon
chr1:93576102-93576183
Coord A exon
chr1:93576184-93580244
Coord C2 exon
chr1:93580245-93580340
Length
4061 bp
Sequences
Splice sites
5' ss Seq
CAGGCAGGT
5' ss Score
2.53
3' ss Seq
ATGTGTTTTAAATATTTTAGGAG
3' ss Score
8.6
Exon sequences
Seq C1 exon
ATAAACATATTGAAACAGAGCTGCTTCATCATATTTGAAGACAGTTCTAAATCCTGGGTTCTCTGGAAGGACATTCAAACAG
Seq A exon
GCAGGTGCTACTATTTCTCTTGAACATGATTTAAATTAAAATTTGATTTTCTTCAACTTGTCATATTATGATGTTGTCTGTTGAATACAGTGTATTTAGATAACTCAGTATTACTTCCTAGGAGAGGTTAAAAAATCAGCATAGTCGTTATTATAGACCATAAGAAGAACAAGAATACTCTAGAGGACAGATGCATCACTAATTTATACCTGTAAGCTATGTTAAGACCCTTCTAAGAACTTTGAAGAAAAATCTTTAGTAACTAATCTCAGTAACGGTTTGGGATTCAATTCAACTGTTGCTTGCTTATATTTGTAGAAAGCAAGTGTTTATTGGGAGCATACTGTTTGTCAGATGATTTGGGAAATTAGGACATATAAAACTGATTTAGAATAATAGAAATATTCGTTAATAAGAATGGTTTAAAATTACCATTTAGTTATGGGTTTTTTATGTTTAAATGGGAAAATGAGGCTATATTTGTGTGCCAATAAAAATGAATGAAAGTATGCCTTGGTTTGGTTATAGGTATGCTTCTTGTGATGATTTCTATTATTAGAAACCATGATTGTTTCATGCTTTTAGCATCTGCTAAATATAGATGTTTTACCAGGTACCTCTTTCATGCAAAGTACTTTTAAAAATTACAATCTCTACTAAAAGCCTGAGTATTTTAGCTGTTCATTAAAGCCCTACTTTTGGTTTTCCTTTTGCTGGGTTAATAGGCCTACACTAAGACCCGTGTTTTGTGTATTCTCATAGAAAAGAGATAAATTTTCTCCCTAAAGGGTAGACACCTTGCCAAAGTATTTAACAATTGGGTTTTATATTTGAATACCAAGTTCAATTTTATGGTAGGTTTCTGCCATGTTTTAGTTCTTGACTTTACTCTTAATGTTTCTTAAAGAATAAAAAAAGTTTTGGTAAAGGAATTGGAATGTTCTAATTACCATCTGTATAGTTGGTACTCAGGGCTTAGGTGGGGAACTAAGTAGCTTTTACTCTGGTAAAATGTTTTTCTGGAGAAACTTTTTATGGTTCCTGGACTGATAAGTTTAAAGGACTAAAATTACATTTTGAATCTGAAATTGAGGAGCCAGAGAAAAGTGTGACTCATAAGATTTAAAGGGATAGGAGATCTCCAACACTACTAATATTGAGCAGATCTTACTACCCTGCACACAAAATTATTCTTTTTTCCTTATTTTGTAAACATAGGTCTCTCTGTAATAGCAGTGAAACATGTTATGCTGCTTTTTACTCCCCTTCCATTAGCTATGTGTTTCTTTCAGCTTTTGAAGATCTTTTGGAGTTTCCTGTGGATTTAATGTAATAGGTCTGTCTGTCCTTTTGTCTACTTCCTCCTTTCTACTTCTCCTCTGCTTTTAAAAGTGGTAGAAAAGAAGAAAACCAATGTTACATAGAGATAGAAAGTTGTTGTGTGAGGGGTTCTATAAGTCCTGCACTCAGTATGTCAGTTTAATGTTCTGTGGTTGTTCTTTCTTCACTGGTTCCTTTTGCTGTTCTTGGAATTACAAAGGATTGCTCCTGGTCATTTAACTCTTCTTAGCACCCTGATATTAGCACATATGAAACTTATAGTTGCTATAAAAATGAATAAATGAATCTGAAACCTGCGTTATGGCATATTTCAGTGAGGAGTGGGTTTAGTAGTTTTCTTCCCTGTAAGAAATCTGCCAATAATGTATATCAAAACTTAATAAATTATATTTGTCTAATGAGTTTCTTTTAAAAATTTTACATAAAGAAAAATATTAGTAGTCAACAGGGTGAAATATATCATGTTACAACTATTACATAAATGTAAGAGGGTTTTGAATCTTAGCATCTAATGCTGTTTTGGTTTCTGTGAAATGATATACTCTTGCATTGCTGGTGGCAGTGTAAATTTCTATTTTGGTGGTTTAGCATTTGCATTAAATGCAGAAGTTTATAATTATCTAATAGACTCCTTTCTAGCAGTTTATTCATAAGAAGTAATTCAAAAAATACTAGGTGAAAAATGTTTCCTGAAGTTTATTTTAACAACAACAAAAAATTTGGTATTTCTAAGATGAAATGGCCAAGGCTTTCTAGTCAATTGGATTTAGAGTAAAGGAGACTATAGAAGATTACTAAGCTATATAGGAAGGTTCTTGTAAACTTGATGGTAAAAAATATATACATATATGTTTGATTTCACAAGTAAAAGTTAATTCCCAGCTTTCTCAGGATTGTTTCTTGGGTCACTACCCCCTTTTCTGAGGAATTGCCTTCCCCATCATTAGTCCAGGTAGTTACAGTGAGAGTCAGGTCAGGCACCTCCCCTCGCGGGGCTGTTGTTCCATTTCCAGGGAATTGTAAATTTTCACAGAGAGTTCCCAGGCTTAATCTGGTTGCTCTCATGATCGGAACCATAAACCCAGAAGCTATGGGAGACCACCTTCAACGAAGTGTACCAAGAAGCAAACAGCTGGGCGCAGTGCCTTATGTCTGCAATCCCAGTGCTTTGGGAGGCCCAGGCAGGAGGATTGCTTGAGCCCAGGAATTTGAGACCAGCTTGGGCAACACAGGGAGATCCTGTCGCTACAAAAAAAAAAAAAAAAATAGGCATGGTGACACACACGCCTGTGGTTCCAGTTACTTGGGAGGCTGAGGTGGGAGCATTGCTTGGGCTTGGGAAGTCAAGGCTGCAGTGAGCTGTGGCTGTGCCACTGCACTCCAGCCTGGATGACACAGCAAGACCCTATCTGAGGGGAAAAATAAAAGGAAGCAAACAAAGCAGAAGAGAGAGGATGAGAGACCAGAACAAACAAATAAATAGCAGAAATACAAAAGACAGATTTCTCCCCCTCCAAAAAAAGAAAAACAGTTGGTAACCTGTATGTCCGAGAGTAGAGTAATAATGAAGTAAATTGGGTTATTTCCACTAGATGTAATACTATGCAGCTATTAGAAGTTACAATTTTGAAATGAAAAATGATTTTCATTTTCAATTTTGAGTGAAAAATGCTTTTGATAGAAGAAATATTACATAGTATTGATGAAGCATCTCGTAGTGGAGAGAACATGGATTTTGGCACATCTGGATTTGAATCCTAGTCTTGATGTTTTCTCAGGGTCTTTGGGTTAGTTACTTTGTCTGAGCCTCAGTTCTTCTCTATAAATAGTATATTTATAAGTTAGTTGTAGAATTAAACAAAATATATCAAGATCCTACACAGTGCTTGGCCCATAGCACAAAATTATAAGTTTTTATTGTTGTTATGTATATAAAGGCTGTGTATTGTGAATTTGACTCTGCTGAAACAGACAAGATGAGAATACTGGAAATGATAATGTGTTAGGGTGGTAAATTGTATTAGAAATTTTGTGTGATTTTTTTTTTTTGAGAATAAAAATGTCTCAGGAAGAAATGCTTCACTTGTTCTGCTAAAAAAAATTAATAATTTTGGGACCCCCAAATTTTGTTGAAATGATATTTTGTTAGGGTACATTATTGGATACCATATTTTCAGATTTCAGAAGCTAGAGATTAAATAATTGGTGTTCAACCTGTTTAATAAATTAGTAAGTAAAAGGAAATGCTCTGAATTGAGCGAGAAAGAGGTAGTTTACTTATCTTCCTTACTTTTTTTCTTTAATTTCATGGTATTAGTGGTGTAGGATAAGTGAATGTATGTACATGAATAGATAAGTATTCTATAAAGTAGCTCTAGTGTTCACAAACCTTCTCTATCTGCTGTCGCCCATCCCTCATCTCCACCTTCACCTTTAAGAGTGGGAATATGAGAAATGAGTAATAAGGGAAGATGCTCAAGAGCAATTTAAATTATGCCTTCTGCCAAAAAGCAGATTAAATTATGAAAGTAGGCATGTTAAGTTAAAGGTAGAAAGAACACAGAGAGCAGAGAGATACCATTCGTGTACTTTGTCTTGTGAAGCATTATGATGTACTTAGCAAACATTGCGCATATGTGCTGCTCACTGAGTCATAAAAGTGGTTTTGTTTTATGGAATTTTTTATGACTCTCTTTTTTAATGTGTTTTAAATATTTTAG
Seq C2 exon
GAGCCACTGGAAGTGGGGAAATGGTCTGTACAATATGTCAAGAAGAGTATTCAGAAGCTCCCAATGAAATGGTTATATGTGACAAGTGTGGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000143033-MTF2:NM_001164392:3
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF150571=DUF4537=FE(42.9=100),PF0013017=C1_1=PU(7.7=14.3)
A:
NA
C2:
PF150571=DUF4537=PD(23.8=45.5),PF0013017=C1_1=FE(61.5=100),PF144461=Prok-RING_1=PU(50.0=84.8),PF0062824=PHD=PU(44.4=72.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)