HsaINT0106392 @ hg19
Intron Retention
Gene
ENSG00000198793 | MTOR
Description
mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]
Coordinates
chr1:11190586-11193254:-
Coord C1 exon
chr1:11193137-11193254
Coord A exon
chr1:11190835-11193136
Coord C2 exon
chr1:11190586-11190834
Length
2302 bp
Sequences
Splice sites
5' ss Seq
AAGGTGATC
5' ss Score
4.41
3' ss Seq
TTGCCTTTCTCCCCAACCAGGCC
3' ss Score
10.07
Exon sequences
Seq C1 exon
ATGCTTCCTGAAACTTGGAGAGTGGCAGCTGAATCTACAGGGCATCAATGAGAGCACAATCCCCAAAGTGCTGCAGTACTACAGCGCCGCCACAGAGCACGACCGCAGCTGGTACAAG
Seq A exon
GTGATCAGAAGCAGGCCACCTGTGAGACCCAGCACCCTGGCTGGCTCGTGTCCTCCTGTGTGCTCGTGGTTACAGCTGAGCTTCTGCGGAGCTAGGCTGATGCTGTGAACTTACTCCTTGAGTCCCTGGAGCCTATCTATAAGAGGCCCAGGGAGCCTGCATTTCCCCCTACAAGTTTAATTAATACAGAAAGATTATTGGAGAAATACTTGTTACACCATTATTATGTGTATGTGGTGTTGGGGATTGCTGCTGTCTTACAGACTCTGAGCTGCTTGTTTTCCTGGGAGCATCTGGACACATGGTTAATCTCTGGAGTGACATCTTCCCTTAGGTCATCTGTTCTTGTTCAGCGTTTTTCTGATTTGCATCCTTGCCTGCTCCTCAGCTAAGAACTTAACTTTCTTTGTTTTTATTGGAAAGATCCAAGTAACATCCTGTTATGTTACAGGAAACTTTTGAAAGAGATAAACAGAATTAGAAAATATATAAAAGATGTGATTGATGGAGGGGTGATTTTTGGAAGTGTATATCTTTGGTGAGAATATACTTTCTTATTTCTTTTTGAGAGGCTTTCTGGTAACTACTTGGTGTGGCAGATGTCATTGACATCTTTCCAGTATTTCCTTGGCTTGCCAATACTTTGTGAATTAATCTCTCTGAAATCTAAACTTGTATCTGAGGACTGCAGAAGCACTTATAATACAGATCTTACCTTTGTTTAGGCATGCTTCATTCTGGTTTGAAAAATGTCCATTTTGTCATAAGAGTAATACTCTCTCTAGGACAGCTTGCATGTCCAAAGCTGGAAAATACATCCGGTAAACACTATTAACTGGAAGCTTATTAATCAGAGTTGTATTCTAACCAGAGTTACTTTCATTCATTAAGCTTTTAGGAAGTAAGCAAATCACAAGAAAAAAGTTGGTTTCAGGAACTTTAGTTTTAGTTTTTAAAAGCTTTTCCTAATGTGGGTCCCTTTTGTTTTATGATGTATTCTACCATCAACGTCATGGCCCTGTATGCATGCCAGGACTGTTTGTCTTGTTCACCTTGACCCCAGGTCATTGCCAGGCACATAGCAGATACACAAGAGATATTCAGTGAATAAATGAAGGTATGGGAAAACTGAAACCTGGGTCATTGTAGAATTCTTACTCATCAAGTAAAGGTTAGTTGTGATCAATCTATTCTCCTTAGTTGAGAAAACGGATACACCTGTGTTCAAGGTTTTTGGCAAGGCATACAAACGAATTTCCCAATTATTCAGAAAGTTCAGCTATTAATGGGTCACGTAGTGTCCTACTATCACTGCAAAGTTACCATGCCTGGAAGCAAACTCTGCCTCACACTCGCTAAACCAAGTGGTGGTACGCTGTAGAGTCATTGCCGCTCAGAACCCCAGAGAGAGTAGTATTCCTTTATCCAAATAAGCACCAGCGGTTCTTCCTTCAAGCATTGAGCACTGGTTCTCTGTCAGGCCGTGGGCTAGGTGTTGGGACCAGGCAGATGGGTGAGATTCTTTCTCTGTCAGGCTCCTATGCTCTTCATGTCTTCCTTTGTCCACTATCTGGTGACCTGTCAAAACTTTGCTCCCTTGAAATATTGTGATGACTGCTGCTTGCCCCCACTTCTGCTTGCCATTTCTGCTCTCCCCTAAATGTACACTTTATACCCAGTGCAGCTCTGCTTTCTGGGTGAAAGTGCCAGCCCTGTGCCTGCTCCAGGCGTGCTTTGCTGGCCTCGCTCTCACTCCTCGCCTGCATGTATCCCCTGCACGGTCACATTCATGGGCTTGTTTCCCGTGAACCAATCTGCACATCTCTGGCCTTATTCTTCCCCCTTGCCAAGTAGTCCCCACCGCTGCCTTCTTGTTTCCCTCCTTGCCCTTCTGCAGCTCTCTTCCAGACCTACCCCAAATCCCTCTTCTTGACAAAGCTTTCCAAATGCCTGTCCTTGCTACTCCCATTGTGCCTTGCAGAGTACCTAGGTCTTCAGGTTTGTGCGTGAGCTCCCCTAGGAGGCCGGGAGATCCCTTGAGGCAAGAGCTCTCTCCTGCTCCTCTTGCTGTGCCCTTCTCGCAGTGCACTCATAGTACGTTATATAGTTAGTGCTCCACAAAGTGAGTGGATCATGTTGAATTTAGTAAAACAGCCATTTCTGAGTGTCTCCTTGAAGTGTTTGCTTTATGGACACACAGAACAGGCAGGAGCAGCTGTTCCTCAGCATCGACCTTGCGCTCCTCTGAGCCCTGCTGTTGGTCACAGCTCCAGTGTCTGTCCTTGCCTTTCTCCCCAACCAG
Seq C2 exon
GCCTGGCATGCGTGGGCAGTGATGAACTTCGAAGCTGTGCTACACTACAAACATCAGAACCAAGCCCGCGATGAGAAGAAGAAACTGCGTCATGCCAGCGGGGCCAACATCACCAACGCCACCACTGCCGCCACCACGGCCGCCACTGCCACCACCACTGCCAGCACCGAGGGCAGCAACAGTGAGAGCGAGGCCGAGAGCACCGAGAACAGCCCCACCCCATCGCCGCTGCAGAAGAAGGTCACTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198793-MTOR:NM_004958:38
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.752
Domain overlap (PFAM):
C1:
PF0225918=FAT=FE(9.8=100)
A:
NA
C2:
PF0225918=FAT=PU(66.4=98.7)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)