MmuINT0102066 @ mm10
Intron Retention
Gene
ENSMUSG00000028991 | Mtor
Description
mechanistic target of rapamycin (serine/threonine kinase) [Source:MGI Symbol;Acc:MGI:1928394]
Coordinates
chr4:148534908-148536759:+
Coord C1 exon
chr4:148534908-148535025
Coord A exon
chr4:148535026-148536510
Coord C2 exon
chr4:148536511-148536759
Length
1485 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
3' ss Seq
ACTCTTCCCCATGCACCTAGGCT
3' ss Score
6.77
Exon sequences
Seq C1 exon
GTGTTTTCTGAAACTTGGGGAGTGGCAGCTGAACCTCCAGGGCATCAACGAGAGCACCATCCCCAAGGTGCTACAGTACTACAGTGCCGCCACAGAGCATGACCGCAGCTGGTACAAG
Seq A exon
GTGAGGGAGGGCTGGTGCTGCCCCAGACCCTCGCTTCTCCACAGAGAAAGCCTGTACCCTGCTTGAGTTCTCCCATGTTCCCATGGTCACAGCCAGGTCCCTGGAATGCCTAAGTCTGTCAGAAGCCCAAGAAATGTGGATCTTCCTTCAGGAAGCCCAGGAAAGCAGAGAAGCTGACAGAGGCTTTGCTTTGAGGGACACTTCCTGTGACAGATGCCCTTGTTTTAGGAGCTCTAGGGCCACCGTGTCTGATGGTCTCACAGATGCCTGTCATCCTAGGAACATCTATGATGTTATGTTACTGGAAACCTTTCTAAAAGACAAACAGTTAGAAAATGTATGAAAGTGGCTAGCTGACTGACCAGCGGGTGCAGAGGCTATCCCTGGAAGGAAGTGTGTATTTTTAGTGCAGCGCATATACATATATATATATATATTCCTTTTCTAAAGGCTTCCAGGTAATAGATGTTTGGTATAACAATGCCATCAATTTCTTTCCAAAATCTTCATCCTTACTAGGAAGTTATAAATTCTTCCCTCTGGGATCAAAGTTGATTTGAAGACCATAGAAACATTTGGAATAAAAAGTGTTTGTCCTCTGCAGATGCTTCACACTGATCTGAAAATTGTGCACTTTGGCTTGGGATGTAGCTCAGTGAGAGAGTATTTGCCTAACATGCACAGAGCAAGGGGCTCCATCTCCAGCAACATGCACACACACATGCACACACACAGAGTGCAGGCTATGATTCTCCTCTATTGATAGCTACATATCCAGAGCTGGCAAATACATCCAGTGAAGGTTTGCTTGTTAGTCAGCTCACAGCCACCTATAGCTCCAGTTCCAGGGGATCTGGTATGCTCTTCTGGCTATCCTAAGTACTAGGCATATATGTGATACACAGAACATGTATGCAGACAAAGCATCCATTAATATAAAATAATTGGGGGCGGGGACCTCAGGAAGCCCCACTTCCTGAGATGAAGCCAGCTGCCTTGGCCTAGCATGCAGACTCCACTGTCTGGTGCTCTAGCAGTTGGCCAGCGGCCCTGACTCTTGCGGGCCTCAAGCTGCACACATGCCCTCCATGTGCCTTTCTTTTTTCCCTGCCAGGAACACCAAGTGCCTGTCTCTGTTCCCTCCTTGTTCAAGGCAAGGCTTAGCCAAATCCCTTTTTTATGGAGCCCTTCAGATCACTGGTATCCCACTGCCCACCTTATCTAGCCCCTACCTGCCCTAAGTTTTGCTTACACTGACCCTCTGGTTGTGACCTCACAGTGCTCACCAAAAAGCCCAGTGCCGTTACTGCTCTCAAGATGAGCTACATTGATCGTAGTAAGGCCCACTTCCTGGGAGTATGTAGCAATGGAGACGCATTCTGCTGATCTTAAGGCACACTCAGAATCCAGCCTTCCACCTCGCTGGGCTTTGCATTAGACGTGAACTAGCCTGTGTCTGCCTTTGACTCTTCCCCATGCACCTAG
Seq C2 exon
GCTTGGCATGCATGGGCAGTGATGAACTTCGAAGCAGTGCTACACTACAAACATCAGAACCAAGCCCGTGATGAGAAGAAGAAGCTGCGTCATGCCAGCGGGGCCAACATCACCAATGCCACCACTGCAGCCACCACTGCAGCCTCTGCTGCTGCTGCCACCAGCACAGAGGGCAGCAACAGTGAGAGTGAAGCTGAGAGCAATGAGAACAGCCCCACCCCGTCCCCTCTGCAGAAGAAGGTCACTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000028991:ENSMUST00000103221:38
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.687
Domain overlap (PFAM):
C1:
PF0225918=FAT=FE(10.0=100)
A:
NA
C2:
PF0225918=FAT=FE(20.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGAAACTTGGGGAGTGGCAG
R:
CAGTGACCTTCTTCTGCAGAGG
Band lengths:
358-1843
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types