HsaINT0107641 @ hg38
Intron Retention
Gene
ENSG00000144821 | MYH15
Description
myosin heavy chain 15 [Source:HGNC Symbol;Acc:HGNC:31073]
Coordinates
chr3:108439737-108441260:-
Coord C1 exon
chr3:108441018-108441260
Coord A exon
chr3:108439914-108441017
Coord C2 exon
chr3:108439737-108439913
Length
1104 bp
Sequences
Splice sites
5' ss Seq
AAGGTACTT
5' ss Score
8.4
3' ss Seq
CTGTCATCTTCTTCCCACAGGTC
3' ss Score
13.27
Exon sequences
Seq C1 exon
GAGCAAGAGACACTGGCAAATGTTGAAGAGCAGTGCGAGTGGCTGATTAAATCCAAGATCCAGCTGGAGGCCAGAGTAAAGGAGCTGTCGGAGAGGGTGGAGGAAGAAGAGGAGATAAATTCTGAGCTGACTGCCAGGGGGCGGAAACTCGAAGATGAATGTTTTGAGTTGAAGAAAGAAATCGATGACCTGGAAACAATGTTGGTGAAGTCAGAGAAGGAGAAGCGTACTACAGAGCACAAG
Seq A exon
GTACTTTTTCCATAATGTTAGTTAAGAAGGCCTAGCAGCCAGAATTCCACTCTCAAATCAGGTTTTGGTATCTGACTTGCTCTATTCAAGTTAATTAACACAGTGGCCTGCAACTTTACAGCATTGAGAGTCAGAACTGGCACAAAATATAGAGTCTGATAAACTATGCTGTCCCAATTCAGATTTCCAATTTGAACTTATGGAACCTTATTTAATCTCCCAAATGAAACATTTTCATTTGTTTCAATCCTATTGCATCTGAACTCTGTAATAGAGTAAAATGGTTTCATCGGGCCTGTAAGAACCCTTTTTTTTTTTTTTGGAAGGAGAGGGAGCATGATATGGTTTGCTAAAAGATAATTTGGGATGTGCCTGAGTCCCCAGCTGTGTCATTGATTTGGAGTTTGACCTTGAAGATGTCACTTTAATTCTAGTTAAGGGCTTTCATGTTTTGTTTTGGCTGAGAGTTTGTTTGAGGGTTTTAACTTGCGCATCTGTGTGTGGATTGAGGACAGTGAGGAGTCCGCATCAAGCCTCTGATACACAATCTCCAAAGTGACACCGTAATTTTGGCAGGCTATTAAGTAGCACTCTTATTTTTATTGATTCCCTTTCATAAAAAGCACATGGGCCTGATACAGTCAACTTCCATGTTTGCATGTTTTATCAGCTGGAACCTTTCTTTAACTGCCACTTTCTTGGGATACTGAGGCACAACACAATCAGTACATGCCATGACTCCTCAAAAGAAATTGCAATTGCTTTTAGTGTTGTTACTGTTATATAATAATGTGAATTAAATTGGCCATCCAATTTAGTTCATATTAATAATGTTAAATAATTATAAATAATGTTAATTATTTACCCATATTAATGTTTAAACAGAATACTCCATTTCCTCACCATGACAGATAACAGATCATTTTTGTGGGAGAAAAACTAAATGTAGCTTTAGAAAGCGTATCAGGAATTTGGCTAAATACAGCTTTTTGTGACATTGGATACCTCATGCGTAGTTTTGGACGACAGAAGAGAAATGACCCTCAGTGTTATGCCCAACTTTCCAGCAGTGGCTTTAATGAAGCTGTCATCTTCTTCCCACAG
Seq C2 exon
GTCAAGAACTTGACTGAGGAAGTAGAGTTTCTAAATGAGGATATCAGCAAACTTAACAGAGCAGCCAAGGTTGTGCAGGAGGCCCATCAGCAGACCCTGGATGACCTGCACATGGAGGAGGAGAAGCTCAGCAGCCTGAGCAAAGCAAATCTGAAGCTGGAACAGCAAGTTGATGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144821:ENST00000273353:24
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.272 A=NA C2=0.508
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(34.9=100),PF131661=AAA_13=PU(12.4=37.0)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(25.3=100),PF131661=AAA_13=FE(24.0=100),PF045827=Reo_sigmaC=PU(23.9=54.2),PF087025=Fib_alpha=PU(15.7=30.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTTGAAGAGCAGTGCGAGTG
R:
GCTGAGCTTCTCCTCCTCCAT
Band lengths:
355-1459
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development