HsaINT0107853 @ hg38
Intron Retention
Gene
ENSG00000092054 | MYH7
Description
myosin heavy chain 7 [Source:HGNC Symbol;Acc:HGNC:7577]
Coordinates
chr14:23420958-23422325:-
Coord C1 exon
chr14:23422180-23422325
Coord A exon
chr14:23421049-23422179
Coord C2 exon
chr14:23420958-23421048
Length
1131 bp
Sequences
Splice sites
5' ss Seq
AAAGTACTG
5' ss Score
-0.75
3' ss Seq
CCATCCCTCCTTCCCCACAGAAA
3' ss Score
11.17
Exon sequences
Seq C1 exon
CTGGAAGGATCCCTGGAGCAAGAGAAGAAGGTGCGCATGGACCTGGAGCGAGCGAAGCGGAAGCTGGAGGGCGACCTGAAGCTGACCCAGGAGAGCATCATGGACCTGGAGAATGACAAGCAGCAGCTGGATGAGCGGCTGAAAAA
Seq A exon
GTACTGTGTCCCCTCCCTGCTGCCCTTCCTCCTCCCCAGCCCATAACAGTACAAGCAGACCCAAGACAGCCATCCTCTGAGGCAACAACCTCACGCAGCCTCCACAAGTGGAGGCGCAAACCATGGGAAAAGGCCTCCCAGGCAAGGGCTTTCCTCCCCTAGTCCCAGATATCAGGGTTAGTTAGATGGTCCTCCCTGGCAAAAAGTCCATTGTATCCCATGAGTCCTTTCTTCTTGTTAGGCACTCAGTGGGAATGAAAATAACAGCCTTCCCCCTTCATACACATCTCTCTTTGGAGACCAGTTCCTTGACATGGAGGAAGGCTCCACATGAGAGCCTCTTAGGAAAGTCCCTTTGTGGCTTTTCACAGAGAGCCCACAGGGCACCAAGAAATGCCCTCACATTAAAGAAGTCAGGGGATCAGGGCCATTTCTTTGTTTTGCTTAACTTGTGGTTCCAATTCTTAGTGTAAGTTCTTCCAAAATGTATAGACTTTCCAGACTTGGTAAACAGTGAGCTTGCAGAACATATTTTGATAATTGAAGGTCTTATGGTGTTTCAGGCTCAGGACTTTGAAAGGCTTTGAGAATCATCATAATCTACATCCTCATCAAGTTTGTGTTTGCACAGGAATCTTCATACCTTCCCAGGCACAGAATGTGTTGAATAAATGAATAAATACACGATCCTATTTGATTCTCAAAACACCTTTTAAGGATGGTATCTTTAATTTCACTTTACCAAAGAGGAAAATAAGTTTCAGAAAGGTTAGCTGAGTTACCCAAAGCAATAGTGACAAAATTAAAGACCATCAGAGCTAAAAAGGACCTTTGAAACAATCTAGTCCGACCCCCTCATTTTACATTATGAGAAAACAAGGACCAAAGATGGGAATGTCCTGTAGAGCCCAGGCCCCATCACCCTGTCTACAGCACTCCTCCCATTACATTCTTGTTGGATTTCAATCTCACCGCAGGTGTTACACTTCCAGGGATCCTACATCACCCCCAGAAGCTGTTTTTCTAATGAAATCCTACTCTTTACCTGTATCATTACCATTTTCAACCACTGGTGGACCCTCCTGAGGCCCCACGAGTCTCCCTTACCTCACCATCCCTCCTTCCCCACAG
Seq C2 exon
AAAAGACTTTGAGCTGAATGCTCTCAACGCAAGGATTGAGGATGAACAGGCCCTCGGCAGCCAGCTGCAGAAGAAGCTCAAGGAGCTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000092054:ENST00000355349:25
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.449 A=NA C2=0.032
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=PD(26.4=69.4),PF0003816=Filament=FE(17.0=100),PF0157614=Myosin_tail_1=PU(1.6=28.6)
A:
NA
C2:
PF0003816=Filament=FE(10.6=100),PF0157614=Myosin_tail_1=FE(3.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGAAGGATCCCTGGAGCAA
R:
TCCTTGAGCTTCTTCTGCAGC
Band lengths:
230-1361
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development