HsaINT0107903 @ hg19
Intron Retention
Gene
ENSG00000078814 | MYH7B
Description
myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acc:15906]
Coordinates
chr20:33586522-33587208:+
Coord C1 exon
chr20:33586522-33586718
Coord A exon
chr20:33586719-33586858
Coord C2 exon
chr20:33586859-33587208
Length
140 bp
Sequences
Splice sites
5' ss Seq
CAAGTGAGT
5' ss Score
9.1
3' ss Seq
TGTCTGGTTCCATGGCCTAGAAA
3' ss Score
3.97
Exon sequences
Seq C1 exon
GCCAAGAGTGCCCTGGCCCACGCCGTGCAGGCTCTGCGGCACGACTGTGACCTCCTGCGGGAGCAACACGAGGAGGAGGCTGAGGCCCAGGCTGAGCTGCAGCGGCTGCTGTCCAAGGCCAATGCCGAGGTGGCCCAGTGGAGGAGCAAGTACGAAGCAGATGCCATCCAGAGGACCGAGGAGCTGGAGGAGGCCAA
Seq A exon
GTGAGTGCTTTGCTGGCCAGGCCACTGCCATGCAGAGCTTTATGCCTGTGCCTGAGCCCCGCTGAGGGTGGGTGAAGGGAGCTGCTGGGGCTGTTCTCCCTCCTTCCATGGTCCACACCTTGTCTGGTTCCATGGCCTAG
Seq C2 exon
AAAAAAGCTGGCACTGCGGCTGCAGGAGGCAGAGGAGGGCGTGGAGGCTGCCAACGCCAAGTGCTCATCGTTGGAGAAGGCCAAGCTGCGGCTACAGACAGAGTCAGAGGATGTAACCCTGGAGCTGGAGCGGGCGACCTCAGCAGCTGCTGCGCTGGACAAGAAGCAGCGGCACTTGGAACGGGCACTGGAGGAACGGCGGCGGCAGGAGGAGGAGATGCAGCGGGAGCTGGAGGCGGCACAGAGGGAGTCCCGTGGCCTGGGCACCGAGCTCTTCCGGCTGCGGCACGGCCACGAGGAGGCACTTGAAGCCCTGGAGACGCTCAAGCGGGAGAACAAGAACCTGCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078814-MYH7B:NM_020884:35
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.197 A=NA C2=0.678
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(7.6=100),PF0003816=Filament=FE(23.7=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(13.6=100),PF0003816=Filament=PD(33.9=78.8),PF045827=Reo_sigmaC=PU(68.2=87.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAACACGAGGAGGAGGCTGAG
R:
TCTGACTCTGTCTGTAGCCGC
Band lengths:
242-382
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)