HsaINT0107904 @ hg19
Intron Retention
Gene
ENSG00000078814 | MYH7B
Description
myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acc:15906]
Coordinates
chr20:33586859-33587498:+
Coord C1 exon
chr20:33586859-33587208
Coord A exon
chr20:33587209-33587373
Coord C2 exon
chr20:33587374-33587498
Length
165 bp
Sequences
Splice sites
5' ss Seq
AGGGTAGGA
5' ss Score
6.45
3' ss Seq
CAGCACCCTGTCCACTGCAGAGG
3' ss Score
5.48
Exon sequences
Seq C1 exon
AAAAAAGCTGGCACTGCGGCTGCAGGAGGCAGAGGAGGGCGTGGAGGCTGCCAACGCCAAGTGCTCATCGTTGGAGAAGGCCAAGCTGCGGCTACAGACAGAGTCAGAGGATGTAACCCTGGAGCTGGAGCGGGCGACCTCAGCAGCTGCTGCGCTGGACAAGAAGCAGCGGCACTTGGAACGGGCACTGGAGGAACGGCGGCGGCAGGAGGAGGAGATGCAGCGGGAGCTGGAGGCGGCACAGAGGGAGTCCCGTGGCCTGGGCACCGAGCTCTTCCGGCTGCGGCACGGCCACGAGGAGGCACTTGAAGCCCTGGAGACGCTCAAGCGGGAGAACAAGAACCTGCAGG
Seq A exon
GTAGGACCTGCCACACGCCAGGGCCAGGGTGCTGCCCTGGGGTCGGAGCAACTTTGAGTTATGGGGGTGCCCTGGTGGGGCCACCCTGGAATCAGGGGTGAGTGGAGTGACCTGGGTGGGAGTACAAGCCATGGGGGTGGCCTCTCAGCACCCTGTCCACTGCAG
Seq C2 exon
AGGAGATCAGCGACCTCACAGACCAGGTGAGTCTCAGTGGGAAGAGCATCCAGGAACTGGAGAAAACCAAGAAGGCGCTGGAAGGCGAGAAGAGTGAGATCCAGGCTGCACTGGAGGAGGCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078814-MYH7B:NM_020884:36
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.678 A=NA C2=0.810
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(13.6=100),PF0003816=Filament=PD(33.9=78.8),PF045827=Reo_sigmaC=PU(68.2=87.3)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(4.8=100),PF045827=Reo_sigmaC=FE(27.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACAAGAAGCAGCGGCACTT
R:
TTCCTGGATGCTCTTCCCACT
Band lengths:
249-414
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)