HsaINT0107912 @ hg19

Intron Retention

Gene

ENSG00000078814 | MYH7B

Description

myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acc:15906]

Coordinates

chr20:33589234-33589888:+

Coord C1 exon

chr20:33589234-33589329

Coord A exon

chr20:33589330-33589750

Coord C2 exon

chr20:33589751-33589888

Length

421 bp

Sequences

Splice sites

5' ss Seq

GCGGTGAGT

5' ss Score

10.49

3' ss Seq

GGCCCTGTGTGTGCCCCCAGGAG

3' ss Score

9.97

Exon sequences

Seq C1 exon

GCCGAGGAGGACAGGAAGAACCTGGCTCGCATGCAGGACCTGGTGGACAAGCTGCAGAGCAAGGTCAAGAGCTACAAGCGCCAGTTTGAGGAGGCG

Seq A exon

GTGAGTGCGCTGGGGCCTGGACACCTGGACCGGGCACCCCAGCTCTGCCCCAGGGTCTGTGGCCAGGTGAGGCATCAGCAGCAGCTCCACCCTCCAAGGTCAGTGACCCAGAGGGAAGAGAGAAGCTTCTAACATCTCTGGGGAGATCAGACCTAGCTCCTTCTCATGGAACAGACCCCATGTGCTTTCCCCTGGCCAAGGCTGGGGCTGCCTCTGAGGGGTGGGGCAGGCACAAAAAGGCACATGAAGTTGGTGCGTCCCAACTTCCTTATTCCCGCTGTGGTATTGGTGAGGATGGACAGTGGCAATAGGAACAAAGTTGAGAACCAGGAGGAGCTAGCTCCCTTCTTGGACTGGGGCAGGGACCAGAATAAGCATCTCAGTCACCCAAGCGGAACCAAGGCCCTGTGTGTGCCCCCAG

Seq C2 exon

GAGCAGCAGGCCAACACCAACCTGGCCAAGTATCGCAAGGCCCAGCACGAGCTGGATGATGCGGAGGAGCGGGCAGACATGGCGGAAACCCAGGCCAACAAGCTGCGGGCACGGACCCGGGACGCCCTGGGCCCCAAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000078814-MYH7B:NM_020884:43

Average complexity

IR-S

Mappability confidence:

NA

Protein Impact

ORF disruption upon sequence inclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.697 A=NA C2=0.927

Domain overlap (PFAM):

C1:

PF0157614=Myosin_tail_1=FE(28.7=100),PF096025=PhaP_Bmeg=FE(25.4=100),PF131661=AAA_13=FE(25.6=100),PF0003816=Filament=FE(28.4=100),PF060097=Laminin_II=FE(45.6=100),PF150701=GOLGA2L5=FE(27.9=100),PF117273=ISG65-75=FE(27.4=100),PF044267=Bul1_C=FE(33.7=100),PF150351=Rootletin=FE(39.7=100)

A:

NA

C2:

PF0157614=Myosin_tail_1=PD(37.0=87.0),PF096025=PhaP_Bmeg=FE(36.9=100),PF131661=AAA_13=FE(37.2=100),PF0003816=Filament=PD(37.6=89.1),PF060097=Laminin_II=PD(13.2=19.6),PF150701=GOLGA2L5=FE(40.5=100),PF117273=ISG65-75=FE(39.8=100),PF044267=Bul1_C=PD(35.9=71.7),PF150351=Rootletin=PD(53.8=91.3)

Main Inclusion Isoform:

NA

Main Skipping Isoform:

ENSP00000262873