HsaINT0108179 @ hg19
Intron Retention
Gene
ENSG00000145555 | MYO10
Description
myosin X [Source:HGNC Symbol;Acc:7593]
Coordinates
chr5:16681980-16684044:-
Coord C1 exon
chr5:16683989-16684044
Coord A exon
chr5:16682123-16683988
Coord C2 exon
chr5:16681980-16682122
Length
1866 bp
Sequences
Splice sites
5' ss Seq
TAGGTAAGC
5' ss Score
8.89
3' ss Seq
CTTCTCATCTTGTGGCTCAGACC
3' ss Score
5.81
Exon sequences
Seq C1 exon
GGCACCTTGGATGTGGGGCTGATTGATTCTGTGTGTGCCTCTGACAGCCCTGATAG
Seq A exon
GTAAGCTCAGATGTGGCTCTTAACAAAAACAGCTCATCACCTGTGTGTGTCCACAGGTGTCTGTGCTGCTGGGTCACGACCCTCTTCACAGGGCTGTGAAATCACGCAAGGCTGTGTGTTCCCACCTTGTCAACCCCAGCAATCCAGTCTTCCTTCTTGGTACCCAATTTTACATCACCTGGAAGTCTCCTTCTCTGGGTATCTTTGGAGTCCTGGGGAAAACCGTGGGAACCTGGACAATTTTAAAAAGCATGAGGAATATTTTTAATGTGTATACAGGGACAAACTTGGGATTTATACAGGAAGAAAATGCCTGTTTAGGAAAATGATATTCCAGCAAAGGGGAAGGGAGTCATTCTCCTTTCTGAACTTAACGATAAACTTGAAAAGGATTTTGATGATAATGTATATGTAGAGTATTAATAAACCACAAACATTGATTTTCCTTGACATTTCTTCTTTCTTGGCACCCTTTTTGGTTTTGATTTTTGAAGGCAAATCATCTTTGGAGATGATCTTACGCGTCTTTGTGCCCAGTGAACTTCATCTTTATTGTCTCTGTTTTTCTGTATTATCTTGTAAGTTCTACTTCTGGCCTGCAGCAGAATTTAAGAAAAGTTTCTCTAGGACGGACCAGAGAAAGAATCAAAATTGTCTTCTGCCCTCAGTAAGATGCTGGAAAGTGAATACGAGTGTGTTAAAATTGACAACAAAATATAGTGCCTCCTTGGCAGAGTTAGAGTGCTGGGGTCTCTGTCAGTCACCCTCCCGTTGACAAGAGCCCTTCTGAACCATGGGTCCTTTGTTTTTAGTAGTCAGCTTGCACCCCTTATAACTGGCTCAGGAATCTTTAACACGTATGTGTCATATCCGTAATCAAAGCCCTGGTGCTTCTTATTCTGGTATGTGAGTTTCTACCTTACCTTCTCCACATCTTTACTCTCCCAAGCCCTTCACTCCTCCAGGCTGGGCATGTGATGATCCATCCTTAGAATTTTGCATCCTCATTCAGGGTTTTCTCTCTTCCTCAACTGGCCACTTTTCTCCCTTGCCAACTATAGAAAAAGGCTTTTTTTATTTTTTATTTTTAAGGGGCACCTCAAGTTTAGCCTGTTTGCATAGCTTTTCCTGTGTCCTGCAGTCCAGTTACTCTTTTTCTTAAATTTTTGTGTCACCTAACTACAGTGAACATTTGAAGACTTGCAAGAAAGAGTTCACATTCTCTAGCTTAAGCCGTTAGATAGAGGAGTTAGTATTTATATTAGCAAGGGCCTATGAGAGAGGTTCAGGGCATTTCCAGACAAAAAGAGGTGAGGGAGAAAGTAAATTTCCATTATCACGTTATCCGTGACTAGGAAATGCACCCTTGTTAGATCACTTTGGAAACCCGGACCCAGGTGGCTTTTTGTATAAAGCGTAATCAAGCATTTAAGATGCTCCACCTACACCTATTTACTGATCCTCTTTTATTGCTGGTGTCTGACATTTCATTACCAACCCACAGAAATATTACCCAAGGCAGGAAGAAATTGACTTTGGAGAGGCATCAAAAAAAAATTTTCCCTCATGGTCACCTTGTTTAGCCTTCCCGGAACTGAGTTTCATCTGGAAAGTTTTGCATGAAGAAATGTTTTCCCTTCCAGGACCTTCAGAATGAATGTGTTGCTCCAAGTTTAAAGGTTAATGATGCGTAAAAGAAATTCTGCAGAAATGAGCAACGTTTGCCTTAATAAAAGCACAGATAGCCTAGCAGTGTATATCCCGTGACCCAGAAGCCAGGAAGAAGGCACTGAGTCTCGGTTCACACAGAGGTGATGCTGACGGTAGGGCTAAGGGGCTTTGTTTCCTTCTCATCTTGTGGCTCAG
Seq C2 exon
ACCCAACTCGTTTGTGATCATCACGGCCAACCGGGTGCTGCACTGCAACGCCGACACGCCGGAGGAGATGCACCACTGGATAACCCTGCTGCAGAGGTCCAAAGGGGACACCAGAGTGGAGGGCCAGGAATTCATCGTGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145555-MYO10:NM_012334:30
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0016924=PH=FE(25.0=100)
A:
NA
C2:
PF0016924=PH=PD(47.2=69.4),PF0016924=PH=PU(3.8=8.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCACCTTGGATGTGGGGC
R:
CTCTCACGATGAATTCCTGGCC
Band lengths:
198-2064
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)