HsaINT0108454 @ hg19
Intron Retention
Gene
ENSG00000141140 | MYO19
Description
myosin XIX [Source:HGNC Symbol;Acc:26234]
Coordinates
chr17:34854919-34856799:-
Coord C1 exon
chr17:34856670-34856799
Coord A exon
chr17:34855005-34856669
Coord C2 exon
chr17:34854919-34855004
Length
1665 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGT
5' ss Score
10.28
3' ss Seq
TTTCTGGGCAAACCTCTTAGCCA
3' ss Score
0.56
Exon sequences
Seq C1 exon
CTGGAGCTTCTGGAATGTGGGCGTGCCCGGGTGCTGGAGCAGTGTGCCCGCTGCATCCAGGGTGGCTGGAGGCGACACCGGCACCGAGAGCAGGAGCGGCAGTGGCGGGCCGTCATGCTCATCCAGGCAG
Seq A exon
GTAGGTGGGCAGGTCACCTGTCAGCACTGCTCACAGACCCCACAGGATGTTGGTTTCCTTTGAAACATAGCTCGTCGAGTCCCCATCTCCTGAAGCTGTGTCCCAGCCTGAAGAGATGTCCCTGTGGTGTGCTGGGATTCAAATTCCCTGTCCCCCTCACTCATAACGTCTCTCCAGTTCAATGGAAACCAAGTCACTCCACAAACAAAGGTGCTCTGTAAGAAGTGGAGGCTAAGCGTTGTCTAAGCGTTGTCTTTAATTCCTTTCTCAGACCCTGACAGCTGTTTAGGCCAACTTTTTTTCCCTTTATGACAACTCAAACCATTACCTGCTGGGCTCTAGGGCTGGAATGAATTTAAGGAGAAGGTAAAAACCAAAAGGAGTTCATCAGATGAAAAGATGTATTAACCAACATGTTCATAGTGGTCTTATTTTGAAAAGGAAAAGTGTTGGAAAGAACCCAAATATCTAACAGTGGTGACATCATGGCCAAATGATGGACTGGACCATCCCTATGATGCAGCTAAGTGTTTTTGAAGAATATTATAAATTTAATGGAGAACCACTTCCAAAATGATATTCATACCTAGATGTCAAACTACATATTAAGGGCGATGCCCTCCTTTTAAGGTGTGTTTGTGTGTGTGTAGGCATTAAAAAATTGTATAAGGAAGCTGGGCACAGTAGTTCGCTCCTGTAATCCCAGCATTTTGGGAGGCTGAGGTGGGAGGATCACTTGAGCCCAGGAATTTCATACCAGCCGGGCAACATGGCAAAACCCTTTCTCTACTAAAAATACAAAAATTAGCCAAGTGTGGTAGTATGCACCTATAATCCTAGCTACTCAGGAGGCTGAGGCAGGAGAATCACCTCAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCACCATTACACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAACAACAAAACATAATTAACCGTGCCTGGTGGCACATGCCTGTAGTCCCAGTTACTCCAGAGGCTGAGGCAAGAGGATTGCTTGAGCCTGGGAGATTGAAGCTACAGCCTTACGGAGGCTACAATAAGCTGTTCGTGCCACTGCACTCCAGCCTGGGCAAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAACAAAAAGAAAAAGAATATGCTGAAATTGCAGAGAAGGGAATAAAAATTACCACCATCTATTAATTGTATCAGTGTTTGGGTATATGGTGATGTGAGATCAGGGATGCATAAAGCGAACAAATTCAACTGAGGATTAAAAACAAAACAAAAAAAAAAGTTTTTAAAGGCACAGACAATCCAGACCCCTCCCATTCCCTGGGTGCTGACCTGGACCCAGCCTGAGACGGGAAGTGATTGCTGGGCCCTCAGCCAGTCCTTCTCCCCAGTGCCCCTTCACTGTGTTGTGTAGGTGTATTCAAGTGTGTGGGCAGTGTAAGGAATGTTTAAAAGCCAATTTTGCCTTATGTATTGATTTTAGAACCTTATTTGTAGCAATTTATTGAAAAAAAAAAAACGTATTTGAAACTTTGACAGCAACTGTGGTGCTGCTGCAGCGAGGTCACTGACAGCTCTAATGGCCCCTTTATTATCTCTTTCCTGTTTCTGGGCAAACCTCTTAG
Seq C2 exon
CCATTCGTTCCTGGTTAACTCGGAAACACATCCAGAGGCTGCATGCAGCTGCCACAGTCATCAAGCGTGCATGGCAGAAGTGGAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000141140-MYO19:NM_025109:20
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0061222=IQ=PU(40.0=18.2)
A:
NA
C2:
PF0061222=IQ=PD(55.0=37.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGAGCTTCTGGAATGTGGG
R:
CTCCACTTCTGCCATGCACG
Band lengths:
215-1880
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)