HsaINT0108975 @ hg38
Intron Retention
Gene
ENSG00000169994 | MYO7B
Description
myosin VIIB [Source:HGNC Symbol;Acc:HGNC:7607]
Coordinates
chr2:127628372-127629826:+
Coord C1 exon
chr2:127628372-127628535
Coord A exon
chr2:127628536-127629644
Coord C2 exon
chr2:127629645-127629826
Length
1109 bp
Sequences
Splice sites
5' ss Seq
CAGGTGCCA
5' ss Score
3.75
3' ss Seq
TAGCCTCCCTGCCCTTACAGATG
3' ss Score
10.05
Exon sequences
Seq C1 exon
GGAGGCCCAGGGCGGGCAGAGGCTGCTGCTCTCCACGATGCATGAGGAGTACGAGTTTGTGTCACCCAGCAGTGTGGCCATCGCTGAGCTGGTGGCCCTGTTCCTGGAGGGCCTGAAGGAGAGGTCCATTTTCGCCATGGCCCTGCAGGACAGGAAGGCCACAG
Seq A exon
GTGCCAGACTGGGTGGGGTGGGGTGGGGTGGGGTGGGGTGGGGGAGGGCCGCGCATGGGGTCTGTAGGTAGGTGGCATGCTCATCTCCACACAGCAGCCACAAGGCAAGCAGAGGGAGGGAAGGCCCCAAAGCTCTGTGGGGGCAGCTTTAGGCAAGGCCCTGCCTTCTTTCAGCCACTGCTTCCTCTTCTACAAAATGAGGGGCTAAAGGAGGTGGTCTCCAGCCCTGCATAGGCCAGCCATGCTCAGCGCTGCACTGCTGCAGAAGCACTGAGAAAGGCCAGCCCCCAGCCCAGGGAAGTTTTGAACACCATCCCCACAGCGCACTGCTGCAAAAGCACCCCATTATCCCATTTTACAGACGTGAGGCCAGAGGCCCAGAGATGGAAGTAGCTCACCCAGGGTCACACAGCTCAAGGGGGTGGGAGCCTAGTTCTTGGCCACAGCTCTCCCACAAGCCAGCACTCCATCGAGAGCTGGGCTGTGTCTGTGGGCTATGGGGGAGCATGGCAAAGCCCCAGGACCCCCGCTGGGCCAGCCTGCTGGCCGGGTGGTCATGGGCGGTGGGTGGTGTGGTTAGTGCAGGGACTTCAGAAGGGGGTGCTGGTTGGGATGTAGCAGAAGAGGCTGTGTGTGGGGTCTTTGGGCAGTGAGAAATGTCAGCCGAGATGTGCTGCCCTATCGCCCCATTCAGTCCTCACGGCCACCGCAGGAGGGAAAGAGGATTGCCATCTCCAAATTCCAGATAAGGAAGGGGTCTAGAGAGGCAGGCAGCACTCAGGCCAGGCGTGGGGACTGCCAGCCTGTGCATCCTCCCCTCCCTCATCCCTGGCTCCTGGTCAGCCCTCCGAGGGTCTCCCAGGGCTAGGGCTGCAGTCAGAGCTCTCGAGCCCCCACCCACCCTGGGCTCTGTGCCTGTGCAGCTGCAGCAGGTGACAGCCGTCTGAGGCCCCTGAGGTTCCAGTCCCACCATCGCTCACTCTTGGAGTGGTCTTCTGCCCACCACTCTATGCCTCGGTTTCATCTGTCAAAGGAGATGACCCACAAAATTCCAGCACAGCCTCTGGCCCCTGCAGAGCCCTCAGCAAATAGCCTCCCTGCCCTTACAG
Seq C2 exon
ATGACACCACCCTCCTGGCCTTCAAGAAGGGGGACCTGTTGGTCCTCACAAAGAAGCAGGGGCTGCTGGCCTCTGAGAACTGGACCCTCGGCCAGAACGACAGGACAGGCAAGACGGGGCTGGTGCCCATGGCCTGCCTCTACACCATCCCCACGGTCACTAAGCCCTCGGCACAGCTGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169994:ENST00000409816:32
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.049
Domain overlap (PFAM):
C1:
PF146041=SH3_9=PU(14.3=14.3)
A:
NA
C2:
PF146041=SH3_9=PD(83.9=77.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGAGGCTGCTGCTCTCCA
R:
GCCGAGGGCTTAGTGACC
Band lengths:
320-1429
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development