HsaINT0118552 @ hg19
Intron Retention
Gene
ENSG00000184792 | OSBP2
Description
oxysterol binding protein 2 [Source:HGNC Symbol;Acc:8504]
Coordinates
chr22:31301824-31303811:+
Coord C1 exon
chr22:31301824-31302056
Coord A exon
chr22:31302057-31302183
Coord C2 exon
chr22:31302184-31303811
Length
127 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
3' ss Seq
CCACTGTGCCTGCCCAGCAGAGA
3' ss Score
5.23
Exon sequences
Seq C1 exon
GGAGAACGCGGAGAACATGTACTACTTCTCAGAGCTGGCCCTGACCCTCAACGAGCACGAGGAGGGCGTAGCGCCAACCGACAGCCGCCTGCGGCCCGACCAGCGGCTGATGGAGAAGGGCCGTTGGGACGAGGCCAATACCGAGAAGCAGCGGCTGGAGGAGAAGCAGCGCCTGTCGCGGCGCCGGCGGCTGGAGGCCTGCGGGCCGGGCAGCAGCTGCAGCTCGGAGGAAG
Seq A exon
GTGAGGCCGGGCGGGAAGGGCGCCCCGGAGGGGAGGAAAGGGGTGCCCGGGTGGGGGTGCCGCAGGGACGGATTCCGGGGGAGCAGGCCACAAGCCCACCCACCAGCCCACTGTGCCTGCCCAGCAG
Seq C2 exon
AGAAGGAGGCGGATGCCTACACGCCACTGTGGTTTGAGAAGAGGCTGGATCCGCTGACCGGGGAGATGGCCTGTGTGTACAAGGGCGGCTACTGGGAGGCCAAGGAGAAGCAAGACTGGCATATGTGCCCCAACATCTTCTGAGCGCCACCCTTGCAACAAATACAGGCGCCTGCACAGCCTGGCCCACCTGTTCATTAATGCACTCAATTTAGTACTGAATGGTCTTTCTCCCAGCCCATTCCCAGCCCTTCCTATTTCCTTTCCTATTTTTTTTTTCTCCCCACACTTTCTTGGGACTCCCACCTTGGAAGGAGGAAGGGCTGACCTGGGTTCTCTCCAGCCCCCAGGTGCGCCGGGTCACCCGTGCCCCTTCATTATGGACCTGGGCCCTACCGGAACCCCTGCCCCAGTTACCACAACTCAGGCCGGCTGGCCCGGGCCATGGGCTGCGCAAATCACCAGCCCCCAACCCAGGGAGGAACTGGCCCCTCCTAGGGAGCCTCTTCGACTTTTTTAGAAAAATGATCTCCATTTCTTTCCAGCCATGATGTTTAGTAAATATTTTTAGTACCGCACTTAGCAGACAGCTTTCCAAGTGTGCTTTCTTGCCACAAAAGTGTCCTGGCAAGAGCCCCTTATTTTTAAGACATCAGGAAGCCAGACCGCTTTGAGTTGGGAGAATTTTGTAGCTCAACATATCAAGTCCTCGATGGTATCTGAGCTGCCCACACCCCCACCTGCCAAGGCCCCACAGAGCCCAAAACAGAAGGGGGCTGCCCCAGCCCAGCAGAGCACAGAGTTTCTGGAGCTCCCATCCACAGATGCAGGAGGGGGTACTGATGGTAACCCCCATGTGGATTTGAGGGCAGCAGTCCCTGGCCTCACCCTAGCCAGCCTGGGTGGCTCCCTAGCCCCAAGAGGCCAGGAAGGGCTGGAAGGCAGGGCCTGCAGGTGCTCCCCGCCCTGAGACCCAGGCCCCAAATCAGCAATAATGAACAAACCCTTGGCCCAGCCTGGGCTGGTGACCTGGGCACCAGAGACCTTGCATCCCTCCTCATCCTAGGAGGCCCCTAGGGGTGCCCCATCTCAGTGTCCCCTGAACTCTTTATTTGCCTAATTTATATATATATATATGAGATATATAAATATATATAAAATAGCTATTTTGCTTAAATTTCTACAGTATGTAAAAGTGAAAAAATGATGAAGACGGGTGCACCTGTCTGAGTTTGGCCCTCATGTGAGCTGTGCCCTTCCCTCTCCTCATGCCCCCTTCCAGCGGCTTCTGCCAACCATGGGGGGCTGGACCACCATGGCCACTGACCCAGCCCCTCAGAATCCCACACTCCAATCCTTTCCATTTCAGTTTAGTCCTAAAAGTTCATCACAGGGTCTTTCTTTCTACTCCAGGACTGGTTTTGTTTTTATATATATAAAAAAAAAAAGTGAAAACACCAATGTGTGAAATGCCTTACAATGCCCACTGGAGAGGCGGGGCGGGGTGGGGCAGGATGGCCCCACTGGGGCTCCTACAGAGCTGTGGAATGTACCTCTCCCCAACACTGTTTTGTTAGCGAGCACCTTTTGACCAGTAATAAAAAACCTTGGCTTTGGAGTTTTCCACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000184792-OSBP2:NM_030758:13
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.686 A=NA C2=0.023
Domain overlap (PFAM):
C1:
PF0123713=Oxysterol_BP=PD(21.8=53.4)
A:
NA
C2:
PF0123713=Oxysterol_BP=PD(8.6=68.8)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTACTTCTCAGAGCTGGCCCT
R:
CTTCTCAAACCACAGTGGCGT
Band lengths:
253-380
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)