HsaINT0124966 @ hg19
Intron Retention
Gene
ENSG00000133056 | PIK3C2B
Description
phosphoinositide-3-kinase, class 2, beta polypeptide [Source:HGNC Symbol;Acc:8972]
Coordinates
chr1:204434347-204439014:-
Coord C1 exon
chr1:204437998-204439014
Coord A exon
chr1:204434448-204437997
Coord C2 exon
chr1:204434347-204434447
Length
3550 bp
Sequences
Splice sites
5' ss Seq
CCGGTGAGG
5' ss Score
9.35
3' ss Seq
CGTCTGCTCTTCTCTTAAAGGTG
3' ss Score
10.73
Exon sequences
Seq C1 exon
GCGCCCAGACACCATGTCACAACCCTCCAGAACTGACGTTGGCAGGAAGTAGAGACTTTGTTGCCTGTGTCCCCCATCCTCACCATGTCTTCGACTCAGGGCAATGGGGAACACTGGAAGTCCCTGGAGTCAGTGGGCATCAGCCGCAAAGAGCTAGCGATGGCCGAAGCCCTGCAGATGGAGTATGATGCCCTGTCCCGGCTCCGGCATGACAAGGAGGAGAACAGAGCCAAGCAGAACGCAGACCCCTCTCTCATCAGCTGGGATGAGCCTGGGGTAGACTTTTACAGCAAGCCAGCAGGAAGGCGGACCGACCTCAAGCTGTTACGCGGTCTCTCTGGCTCTGATCCTACCCTTAACTACAACTCACTCTCCCCACAGGAAGGGCCGCCCAACCACTCTACCTCCCAAGGGCCACAGCCTGGCTCAGATCCCTGGCCCAAAGGCTCCCTGTCTGGAGACTATCTCTACATTTTTGATGGTTCAGATGGGGGAGTCTCTTCGTCCCCAGGACCAGGGGACATAGAGGGCTCTTGCAAGAAACTATCCCCACCTCCTCTGCCTCCCCGAGCTTCTATCTGGGATACCCCTCCCCTGCCTCCCAGAAAGGGGTCCCCCTCATCCTCCAAGATCTCCCAGCCCAGTGACATCAACACTTTCTCTTTGGTCGAACAATTGCCGGGCAAACTGCTAGAGCATCGGATCCTAGAAGAGGAAGAGGTGCTGGGAGGTGGGGGTCAGGGGCGCCTACTGGGGTCTGTGGACTATGATGGTATCAATGATGCAATTACTAGGCTCAACTTGAAATCGACCTATGATGCGGAGATGTTGCGGGATGCCACCAGGGGCTGGAAGGAGGGCCGAGGGCCGCTGGACTTCAGCAAAGACACCTCTGGAAAACCCGTGGCCAGGAGCAAGACTATGCCCCCTCAGGTGCCCCCCCGCACCTATGCCTCCCGCTATGGCAACCGAAAGAATGCGACGCCTGGCAAGAACCGCCGGATTTCTGCAGCCCCG
Seq A exon
GTGAGGACCTTCTTGTGTTTCTTCTGCCTTCCTTTCTCCATGTCCTTCAGAAACAGGGACTAGTCTCTGCTGTTCTACATCCAACTCTGCCAAGTCCTTACCCCTTTAGGCCTCTCCTACCCTCTTTGGGACCCTGGCCCTGGTGGGGGAGGTCCAGGGGAGGCTTGATTAGGGGTGGACACCAGTAGAGGGAGGGCTCCTTCTCAGGGCCAGGTTTCATGTATCTTGGCCAAAACGGGCCTTCTGGGGCAGGCATTTGGGAATCCTGGTTCCTAGCGTGTGCCTGCTTCCTGATGTAAGGACTGAATTGGGAGTTATGGGATTCATTATTGACTGGCTGAATGGCCCTCTGGACCGGAGCAAGTTGCTTCCGCTTGCTCTGAGGCCCTGCTCTGCCAAAAACGCTGCGTGGCGATGAAGATCATTCACAATAGTAACCACTTGTTTAGTGCCCACTGAATGCCAGACCCTGGTCCAGATCTCCACAACAACCCTTCCTGATAGTCCAAAGCCACACAGCAAGCAATAGCAGGGCCAGCATTCAGCCCTGGCCTCTCTCGTTCCTAAGCCTTCTGTCTCCTCCTCTCCTTCTCCCTTTCTCTCTCTCTCTCTCCCTGCTCTGTTCTTTATTGTGATAAAATATACGTAACGTAAAATTCGCCACCGTAACCATTTGGAAGTGTGCAGTCAGTGGCACTGACGACATTCACATTGTCGTGCAACCCTTGCATTATTCATCTCTACTCATTCTCTTCTCACAATGAAAATATTTAGAAAAAATATGCAGTATGACAAATAGTTTTATTTTTATCAGTACATAGTGTAAAATAGCGAACTATCTAGGTCAAAGCCCCCAGGCAGGTGCCAGGGCAGCTCTGATCTTTTTTCTGGTTTAGGGGAGCTTCAGCAGCATCTCCTGGGTAGGACCAGAAGGCCTATTTGTGTTTCATCCTTGGTCCCTGGAAACCCTGGCTGCAAGGAGTCAAGAGACAAGTGACACCCCCATGGCTGATGCCTTCTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTCACCAGGCTTTAGTGCAGTGGCGCTATCTTGGCTCACTGCAGCCTCTGCCTCCCGGGTTCAAGAGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCACCTGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCACATTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCTGTCCACTTTGGCCTCCCAAAGTTCTGGGATTACAGGTGTAAGCCAATGCCCCTGGCTGCTGATGCCTTCTGTGACAGCTTAGCATTCTACTTCATTCTGTCCTGGTTTCCTCCTTAGCCATTGTTTAAGGGGCACTGGGGTTTTCCCACCTTGTGTCTAGCCTTTGGGAACCTTCCCAACTCTGAAGAGCTACACAGTTCTTCCTTCCTCCGCTTCTCCTAAGAGAGTCCCCCCAAAAGCAGAATCAGCTCCTGGGATAAGCCACATCCCTAGAGCTCAGGGATTTTTAAAGGCCCTGCTCTGAGAGGTGGGGCTGTTCCCGCTATTTATAGGGACTGGGAGATTCCTGTTCCCAGCTCTGAGTTCCTCACACCCAGCTGGGCCTGCTCACTGAGTCAGGGCACCCTGGTAGGTGGTCACCTCTGTCACTCCTTCTCTCTCCTGCCTCCCCTACTCCCTCACCCTTCCCCATCCCCTGCATGTCATCAGAGTTCTGAGACAGAGCTCAGCCCAGAATCTCCTTGAAGAAGCGGACACAAAGCAAAAAGCTCTTGCCAGTTCTGAGTGGGGAAATGCGGCCTTGGTCCTCCCCGGCTCAGCTTGTTGCAGGGGCTCAGCCTGCTGGGAGGGGGGACCCCTTGGGCCCTCGGCCTATACCACCGCCCCGCTTTCGTCGGGCTTCCAGCCAGAGGGAACCTCCTTATCCCAGGCCAGCGGAGCCAGCTCTGGAACTGGCTGGCTCCAAATGCCAGCCTGATACCCCTGCTGCCAGCCTCTGCCCGGCAGACTCCCCCAGCCAGCATCGGGTGATGCCACCAGGGCCTGCCAGCTGGGCAAACGTAAGTGGCTTTTGTTTTCTTATGGTGCCAGTGAGTGGTACAGAAAGGACATGAGAGTGGCCTTCAGTGACCACTCTGTTCTCTCCCTCTCTTGCCTTCTCTTCCCTCCCCCCACTGTCTCTCTCTCTTTCTCTTTTTCTTCCTCTCTCTCTCCTTTCTCTTGTGGGTTAATTGCTGACAGTGGTGCTATTGTTTTGACTGGGACACAGGCACGAACTTGGCAGAGCCAGGGCCTCACATGCCAACTGTCCCCACTGCTGCCCTCCCCTCTGTGCACCCCCACCCCCCGCCGCCCATGCACACCCAGGGGAGCAAGCCTAACAAGAGAGGGTCAACCAGAGGAAACAGTCTGGATATTCAAATGAGGAGCTCAGTTGCTGTCATCTGCCCCAAGAGGCAGAGAGGACTTGAGAGTAGCCAAGAGGTTGGGTGAGAGATGTGAGGCGTTGCTATGTGCACAGGCCGGAGCTAGACTCCCGCCAGAAACAGCTGTTGGAACCACATGCCGGCCTTATCTCCATCTGAGCTGAAGCCTCGTCCCTGGTGTGGCCTCCCAGGCTGCCCTGAGCAGACCCCTCAGGCAGAAACCTGTCATGCACCAGCTCTCCCTCCCCCTCACTTCCTTCTCCCTAGGGCTGGGCTACAGGCCTTGCTAGGGGCTTCTTTAGGAACCCTCCTGGGTGACTGAAAGCAGCTCTGGGATGGGAGACCGTTTGGGACCTTGTCTGAGAATCCTACCACCACACACGTATTTTGAGAGAGGAAGTGGGGCCAAGGCAGGCTCCCTGACATTCCGGCCGTTCAGAGCCGGCTGACTCGGAAGCCAGAGGAGCCAAGCTTCTACCAGGTCCTCCCCTGCCCAGACCACTGCTTTGACGCTTTCTTCCTCAAATAGCATTTACCCAGAAGGCACATGTGTCTGAGTCATCTCCTCTATCTAAGGGTTCTGGGTCTCTCTCTGCTTTGGGTCCATGGGGCTTGTGGATATTGAGGCTTTAGACCAGGGCCAAGCTTCCCTGGGCACCATTTGGGCCGCCCACCTGCTCTAGCCTCAGTAGAGGGGCTGGGAAAAACAGCTGTCTGCTCTGCTCCCTGTCACGCCTCTGGGAGAATCCCCCGGAAAGCCCGTGTTGCAGGAGAGGCCCAACAGCACTGGATTGCCTTACTGGCTGCCTCACGCTTATCAGACTGTCCCCTCCTGAAGTGGCTTTGGCCACACTCTTGTCCATCTCAGCCAGAGCTTCGCCTCCTTCTTCAACTTGGCTCCTGGTCTCCTAGGACAGCAGATACATGTATTCCCGGATGTCCCATATGTTCTTGTGCCCCTTTCATTGGATGTCGAGTGACTAGAAAGTCTTTTCATCTAGAGTTTGAGTTTAGGTCTGGAGTACCTCATAGGGAGGGGACACCACGAGGAAAAAGGCACTGAGTCGTCTGCTCTTCTCTTAAAG
Seq C2 exon
GTGGGCTCCCGGCCCCACACTGTTGCCAATGGCCATGAGTTGTTTGAGGTCTCAGAAGAGAGAGATGAGGAGGTTGCTGCATTTTGCCACATGCTGGATAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133056-PIK3C2B:NM_002646:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.814 A=NA C2=0.347
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)