HsaINT0124966 @ hg38
Intron Retention
Gene
ENSG00000133056 | PIK3C2B
Description
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta [Source:HGNC Symbol;Acc:HGNC:8972]
Coordinates
chr1:204465219-204469886:-
Coord C1 exon
chr1:204468870-204469886
Coord A exon
chr1:204465320-204468869
Coord C2 exon
chr1:204465219-204465319
Length
3550 bp
Sequences
Splice sites
5' ss Seq
CCGGTGAGG
5' ss Score
9.35
3' ss Seq
CGTCTGCTCTTCTCTTAAAGGTG
3' ss Score
10.73
Exon sequences
Seq C1 exon
GCGCCCAGACACCATGTCACAACCCTCCAGAACTGACGTTGGCAGGAAGTAGAGACTTTGTTGCCTGTGTCCCCCATCCTCACCATGTCTTCGACTCAGGGCAATGGGGAACACTGGAAGTCCCTGGAGTCAGTGGGCATCAGCCGCAAAGAGCTAGCGATGGCCGAAGCCCTGCAGATGGAGTATGATGCCCTGTCCCGGCTCCGGCATGACAAGGAGGAGAACAGAGCCAAGCAGAACGCAGACCCCTCTCTCATCAGCTGGGATGAGCCTGGGGTAGACTTTTACAGCAAGCCAGCAGGAAGGCGGACCGACCTCAAGCTGTTACGCGGTCTCTCTGGCTCTGATCCTACCCTTAACTACAACTCACTCTCCCCACAGGAAGGGCCGCCCAACCACTCTACCTCCCAAGGGCCACAGCCTGGCTCAGATCCCTGGCCCAAAGGCTCCCTGTCTGGAGACTATCTCTACATTTTTGATGGTTCAGATGGGGGAGTCTCTTCGTCCCCAGGACCAGGGGACATAGAGGGCTCTTGCAAGAAACTATCCCCACCTCCTCTGCCTCCCCGAGCTTCTATCTGGGATACCCCTCCCCTGCCTCCCAGAAAGGGGTCCCCCTCATCCTCCAAGATCTCCCAGCCCAGTGACATCAACACTTTCTCTTTGGTCGAACAATTGCCGGGCAAACTGCTAGAGCATCGGATCCTAGAAGAGGAAGAGGTGCTGGGAGGTGGGGGTCAGGGGCGCCTACTGGGGTCTGTGGACTATGATGGTATCAATGATGCAATTACTAGGCTCAACTTGAAATCGACCTATGATGCGGAGATGTTGCGGGATGCCACCAGGGGCTGGAAGGAGGGCCGAGGGCCGCTGGACTTCAGCAAAGACACCTCTGGAAAACCCGTGGCCAGGAGCAAGACTATGCCCCCTCAGGTGCCCCCCCGCACCTATGCCTCCCGCTATGGCAACCGAAAGAATGCGACGCCTGGCAAGAACCGCCGGATTTCTGCAGCCCCG
Seq A exon
GTGAGGACCTTCTTGTGTTTCTTCTGCCTTCCTTTCTCCATGTCCTTCAGAAACAGGGACTAGTCTCTGCTGTTCTACATCCAACTCTGCCAAGTCCTTACCCCTTTAGGCCTCTCCTACCCTCTTTGGGACCCTGGCCCTGGTGGGGGAGGTCCAGGGGAGGCTTGATTAGGGGTGGACACCAGTAGAGGGAGGGCTCCTTCTCAGGGCCAGGTTTCATGTATCTTGGCCAAAACGGGCCTTCTGGGGCAGGCATTTGGGAATCCTGGTTCCTAGCGTGTGCCTGCTTCCTGATGTAAGGACTGAATTGGGAGTTATGGGATTCATTATTGACTGGCTGAATGGCCCTCTGGACCGGAGCAAGTTGCTTCCGCTTGCTCTGAGGCCCTGCTCTGCCAAAAACGCTGCGTGGCGATGAAGATCATTCACAATAGTAACCACTTGTTTAGTGCCCACTGAATGCCAGACCCTGGTCCAGATCTCCACAACAACCCTTCCTGATAGTCCAAAGCCACACAGCAAGCAATAGCAGGGCCAGCATTCAGCCCTGGCCTCTCTCGTTCCTAAGCCTTCTGTCTCCTCCTCTCCTTCTCCCTTTCTCTCTCTCTCTCTCCCTGCTCTGTTCTTTATTGTGATAAAATATACGTAACGTAAAATTCGCCACCGTAACCATTTGGAAGTGTGCAGTCAGTGGCACTGACGACATTCACATTGTCGTGCAACCCTTGCATTATTCATCTCTACTCATTCTCTTCTCACAATGAAAATATTTAGAAAAAATATGCAGTATGACAAATAGTTTTATTTTTATCAGTACATAGTGTAAAATAGCGAACTATCTAGGTCAAAGCCCCCAGGCAGGTGCCAGGGCAGCTCTGATCTTTTTTCTGGTTTAGGGGAGCTTCAGCAGCATCTCCTGGGTAGGACCAGAAGGCCTATTTGTGTTTCATCCTTGGTCCCTGGAAACCCTGGCTGCAAGGAGTCAAGAGACAAGTGACACCCCCATGGCTGATGCCTTCTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTCACCAGGCTTTAGTGCAGTGGCGCTATCTTGGCTCACTGCAGCCTCTGCCTCCCGGGTTCAAGAGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCACCTGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCACATTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCTGTCCACTTTGGCCTCCCAAAGTTCTGGGATTACAGGTGTAAGCCAATGCCCCTGGCTGCTGATGCCTTCTGTGACAGCTTAGCATTCTACTTCATTCTGTCCTGGTTTCCTCCTTAGCCATTGTTTAAGGGGCACTGGGGTTTTCCCACCTTGTGTCTAGCCTTTGGGAACCTTCCCAACTCTGAAGAGCTACACAGTTCTTCCTTCCTCCGCTTCTCCTAAGAGAGTCCCCCCAAAAGCAGAATCAGCTCCTGGGATAAGCCACATCCCTAGAGCTCAGGGATTTTTAAAGGCCCTGCTCTGAGAGGTGGGGCTGTTCCCGCTATTTATAGGGACTGGGAGATTCCTGTTCCCAGCTCTGAGTTCCTCACACCCAGCTGGGCCTGCTCACTGAGTCAGGGCACCCTGGTAGGTGGTCACCTCTGTCACTCCTTCTCTCTCCTGCCTCCCCTACTCCCTCACCCTTCCCCATCCCCTGCATGTCATCAGAGTTCTGAGACAGAGCTCAGCCCAGAATCTCCTTGAAGAAGCGGACACAAAGCAAAAAGCTCTTGCCAGTTCTGAGTGGGGAAATGCGGCCTTGGTCCTCCCCGGCTCAGCTTGTTGCAGGGGCTCAGCCTGCTGGGAGGGGGGACCCCTTGGGCCCTCGGCCTATACCACCGCCCCGCTTTCGTCGGGCTTCCAGCCAGAGGGAACCTCCTTATCCCAGGCCAGCGGAGCCAGCTCTGGAACTGGCTGGCTCCAAATGCCAGCCTGATACCCCTGCTGCCAGCCTCTGCCCGGCAGACTCCCCCAGCCAGCATCGGGTGATGCCACCAGGGCCTGCCAGCTGGGCAAACGTAAGTGGCTTTTGTTTTCTTATGGTGCCAGTGAGTGGTACAGAAAGGACATGAGAGTGGCCTTCAGTGACCACTCTGTTCTCTCCCTCTCTTGCCTTCTCTTCCCTCCCCCCACTGTCTCTCTCTCTTTCTCTTTTTCTTCCTCTCTCTCTCCTTTCTCTTGTGGGTTAATTGCTGACAGTGGTGCTATTGTTTTGACTGGGACACAGGCACGAACTTGGCAGAGCCAGGGCCTCACATGCCAACTGTCCCCACTGCTGCCCTCCCCTCTGTGCACCCCCACCCCCCGCCGCCCATGCACACCCAGGGGAGCAAGCCTAACAAGAGAGGGTCAACCAGAGGAAACAGTCTGGATATTCAAATGAGGAGCTCAGTTGCTGTCATCTGCCCCAAGAGGCAGAGAGGACTTGAGAGTAGCCAAGAGGTTGGGTGAGAGATGTGAGGCGTTGCTATGTGCACAGGCCGGAGCTAGACTCCCGCCAGAAACAGCTGTTGGAACCACATGCCGGCCTTATCTCCATCTGAGCTGAAGCCTCGTCCCTGGTGTGGCCTCCCAGGCTGCCCTGAGCAGACCCCTCAGGCAGAAACCTGTCATGCACCAGCTCTCCCTCCCCCTCACTTCCTTCTCCCTAGGGCTGGGCTACAGGCCTTGCTAGGGGCTTCTTTAGGAACCCTCCTGGGTGACTGAAAGCAGCTCTGGGATGGGAGACCGTTTGGGACCTTGTCTGAGAATCCTACCACCACACACGTATTTTGAGAGAGGAAGTGGGGCCAAGGCAGGCTCCCTGACATTCCGGCCGTTCAGAGCCGGCTGACTCGGAAGCCAGAGGAGCCAAGCTTCTACCAGGTCCTCCCCTGCCCAGACCACTGCTTTGACGCTTTCTTCCTCAAATAGCATTTACCCAGAAGGCACATGTGTCTGAGTCATCTCCTCTATCTAAGGGTTCTGGGTCTCTCTCTGCTTTGGGTCCATGGGGCTTGTGGATATTGAGGCTTTAGACCAGGGCCAAGCTTCCCTGGGCACCATTTGGGCCGCCCACCTGCTCTAGCCTCAGTAGAGGGGCTGGGAAAAACAGCTGTCTGCTCTGCTCCCTGTCACGCCTCTGGGAGAATCCCCCGGAAAGCCCGTGTTGCAGGAGAGGCCCAACAGCACTGGATTGCCTTACTGGCTGCCTCACGCTTATCAGACTGTCCCCTCCTGAAGTGGCTTTGGCCACACTCTTGTCCATCTCAGCCAGAGCTTCGCCTCCTTCTTCAACTTGGCTCCTGGTCTCCTAGGACAGCAGATACATGTATTCCCGGATGTCCCATATGTTCTTGTGCCCCTTTCATTGGATGTCGAGTGACTAGAAAGTCTTTTCATCTAGAGTTTGAGTTTAGGTCTGGAGTACCTCATAGGGAGGGGACACCACGAGGAAAAAGGCACTGAGTCGTCTGCTCTTCTCTTAAAG
Seq C2 exon
GTGGGCTCCCGGCCCCACACTGTTGCCAATGGCCATGAGTTGTTTGAGGTCTCAGAAGAGAGAGATGAGGAGGTTGCTGCATTTTGCCACATGCTGGATAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133056:ENST00000367187:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.814 A=NA C2=0.330
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development