HsaINT0132646 @ hg19
Intron Retention
Gene
ENSG00000110844 | PRPF40B
Description
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:25031]
Coordinates
chr12:50028321-50029046:+
Coord C1 exon
chr12:50028321-50028385
Coord A exon
chr12:50028386-50028881
Coord C2 exon
chr12:50028882-50029046
Length
496 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGC
5' ss Score
9.88
3' ss Seq
ACTCCTACCCTCTATCCCAGTGC
3' ss Score
7
Exon sequences
Seq C1 exon
GCTGTCCCCTCCAATGCCTCATGGGAACAGGCCATGAAGATGGTGGTCACCGACCCCCGTTACAG
Seq A exon
GTAGGCCTGGGCAGAGGGAGCCAGGCCCTGTTCATGAGAGCAGCTGTGCTAGGGACTCCCTAAAAAACCCCAGCTCAACACTCAGCCCTAAGGGAACCAGAGTCAGGACAGTGATAGATTGGGTTGGGGTGCAAGGGGAAGAAAAGCTGGAGGGCCTCCAGGAGAAGGAAAGGAAAGGTATCTGACACAACACGTTCAATAAATGCTTCCTGAATTGAATCAAACGGAATTGAATTAATTGGGGAATGAGGGTGCTGGATAGGGTGACTTGAGAACCCCAAAGGAAAAGGGCCCAGTATTTGCAGTGTCTTGGAGCTGCATCTCTTCCCCTCACTTCCTGTCACCCCTACTTCTCCATGAATGGTGTTCAGATCCCAGACATCTGTGCCCTTGGAGCCCCTGCAGCCTGCAGTGTCTCATGACCCTCCAGTGTGGGCTGTGCAGAGTGGTTCGGGTGACTTCTCTATCCCCACCCCACTCCTACCCTCTATCCCAG
Seq C2 exon
TGCCTTGCCTAAACTGAGTGAGAAAAAGCAGGCATTCAATGCCTACAAGGCGCAGCGGGAGAAGGAGGAGAAGGAGGAGGCCCGGCTAAGGGCCAAAGAGGCCAAGCAGACCCTGCAGCATTTCCTGGAGCAGCATGAACGCATGACCTCCACCACCCGCTACCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000110844-PRPF40B:NM_001031698:11
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.909 A=NA C2=0.875
Domain overlap (PFAM):
C1:
PF0184614=FF=FE(42.0=100),PF0394210=DTW=FE(18.3=100)
A:
NA
C2:
PF0184614=FF=PD(30.0=26.8),PF0394210=DTW=PD(42.6=87.5),PF0184614=FF=PU(44.0=39.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGTCCCCTCCAATGCCTC
R:
CGGTAGCGGGTGGTGGAG
Band lengths:
230-726
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)