HsaINT0137682 @ hg19
Intron Retention
Gene
ENSG00000111344 | RASAL1
Description
RAS protein activator like 1 (GAP1 like) [Source:HGNC Symbol;Acc:9873]
Coordinates
chr12:113553440-113553856:-
Coord C1 exon
chr12:113553739-113553856
Coord A exon
chr12:113553594-113553738
Coord C2 exon
chr12:113553440-113553593
Length
145 bp
Sequences
Splice sites
5' ss Seq
GAGGTGGGT
5' ss Score
7.07
3' ss Seq
TGTCTCCCGCCCCCACCCAGGAG
3' ss Score
7.76
Exon sequences
Seq C1 exon
GGGGAACCTGGGTGCCCTGCGAGTGAAGGTACGCCTGATTGAGGACCGCGTCCTGCCCTCCCAGTGCTACCAGCCTCTCATGGAGCTGCTCATGGAGTCTGTGCAGGGGCCAGCAGAG
Seq A exon
GTGGGTGCGTCAGGCAAGCAATGCTATCAGGCGGGTGCCGGGGGTCTGGATCCTGGCCTCCCCCTGCCTCACGGAGCCCTATCTAGGCCCATCTGCTTTGGGGTCCCAGGGGCCGAGGTCATCTTTGTCTCCCGCCCCCACCCAG
Seq C2 exon
GAGGACACTGCTAGCCCCTTGGCTTTGCTGGAAGAGCTGACCTTGGGGGACTGCCGCCAGGACCTTGCCACCAAGCTGGTGAAACTCTTTCTTGGCCGGGGACTGGCTGGGCGCTTTCTGGACTATCTCACCCGGCGTGAGGTGGCTCGGACCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000111344-RASAL1:NM_004658:10
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.050 A=NA C2=0.019
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0061614=RasGAP=PU(6.8=25.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCCTGCGAGTGAAGGTA
R:
GCCGGGTGAGATAGTCCAGAA
Band lengths:
242-387
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)