HsaINT0137682 @ hg38
Intron Retention
Gene
ENSG00000111344 | RASAL1
Description
RAS protein activator like 1 [Source:HGNC Symbol;Acc:HGNC:9873]
Coordinates
chr12:113115635-113116051:-
Coord C1 exon
chr12:113115934-113116051
Coord A exon
chr12:113115789-113115933
Coord C2 exon
chr12:113115635-113115788
Length
145 bp
Sequences
Splice sites
5' ss Seq
GAGGTGGGT
5' ss Score
7.07
3' ss Seq
TGTCTCCCGCCCCCACCCAGGAG
3' ss Score
7.76
Exon sequences
Seq C1 exon
GGGGAACCTGGGTGCCCTGCGAGTGAAGGTACGCCTGATTGAGGACCGCGTCCTGCCCTCCCAGTGCTACCAGCCTCTCATGGAGCTGCTCATGGAGTCTGTGCAGGGGCCAGCAGAG
Seq A exon
GTGGGTGCGTCAGGCAAGCAATGCTATCAGGCGGGTGCCGGGGGTCTGGATCCTGGCCTCCCCCTGCCTCACGGAGCCCTATCTAGGCCCATCTGCTTTGGGGTCCCAGGGGCCGAGGTCATCTTTGTCTCCCGCCCCCACCCAG
Seq C2 exon
GAGGACACTGCTAGCCCCTTGGCTTTGCTGGAAGAGCTGACCTTGGGGGACTGCCGCCAGGACCTTGCCACCAAGCTGGTGAAACTCTTTCTTGGCCGGGGACTGGCTGGGCGCTTTCTGGACTATCTCACCCGGCGTGAGGTGGCTCGGACCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000111344:ENST00000261729:10
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.050 A=NA C2=0.019
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0061614=RasGAP=PU(6.8=25.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCCTGCGAGTGAAGGTA
R:
GCCGGGTGAGATAGTCCAGAA
Band lengths:
242-387
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development