HsaINT0176823 @ hg38
Intron Retention
Gene
ENSG00000144357 | UBR3
Description
ubiquitin protein ligase E3 component n-recognin 3 (putative) [Source:HGNC Symbol;Acc:HGNC:30467]
Coordinates
chr2:170006990-170008940:+
Coord C1 exon
chr2:170006990-170007190
Coord A exon
chr2:170007191-170008803
Coord C2 exon
chr2:170008804-170008940
Length
1613 bp
Sequences
Splice sites
5' ss Seq
CCAGTAAGC
5' ss Score
5.34
3' ss Seq
ATGTTTGCATTTTTTTATAGTCA
3' ss Score
7.09
Exon sequences
Seq C1 exon
AATGACCAGGTTCTTCAGGGCTTCTCGGTGGACAAAGGAGAATTCACGTGTCCACTCTGTAGGCAGTTTGCTAACAGTGTTCTTCCATGTTATCCTGGAAGCAATGTGGAAAATAACCCTTGGCAACGTCCTAGCAACAAAAGCATACAAGATCTCATAAAGGAAGTGGAGGAGCTGCAGGGACGACCGGGAGCTTTCCCA
Seq A exon
GTAAGCATCAGTGTAAGGCATAAATATCCTGGTTAACTCAGCTCTGATTTTCTGCTTTCATTTTAATTCAGTTTATAAATTACTCTGGACTTTTACATATTTAGTAGAAATTGCTTTTAGAGGTTTTGTTCTCTTCTATTTATACTTAAATAAAAGTAATAGAACAAATTATTATCAAAGGCTATACTTCTCTTTAGGCTAAATTCTGAGTTTTAATATACGTCTTCTAGGTCAAGAACCCCTATAGGTTTAGATGGAGTTAGCCTCTTTTAAGATGTTCAAATAGGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGACAGATAACTTAAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGCGCTGAGACAGACAGATCACTTAAGGTCAGGAGTTTGAAACCAGCCTGACCAACATGGCAAAACCGCATCTCTACTAAAAATACAAAAATTGGCCGGGCACAGTGGCACACACATGTAATCCCAGCTACACGGGAGGCTGAGGCAGGAGAATTGCTTAAACCCAGGAGCCGGAGGTTGCAGGGAGCTGGGATCGTGCCACTCCACTCCAGTCTAGGCAGCAGAGCGAGACTCCCTCTCAAAATAAAAAAGATGTTGAATTATTTAAAAAACAAGCTATATATACTCTGTGTGTGTGTGTGTGTGTATGTATCTCAATATAAAACACAATTTAATCACTTAAAAATATGCCCATTAGGTATATTAGGATTAAGAAGATATATTTACACAGACATGCACATGTATTTACTGTGTGTATGTGTATTCGAGAGATAAAATATTGTGTAATTGATTGAACTGTTCATCACAAGTCAGACTACTGTAGGGGGGAACTCATCTTTTATCCCATCCAGTAGGATTTGTTTGGTCTAAATTCTTAAAATATTTCACCTTCATAAAAAAAAATTTCACCTTCATTATAGATTTGTGATATGGTCTCTGAGAGAAGTGACAGCTGTGTCTGGTTTATGTAGTAAATTTGTGAAAATTGTGAATATTTGACTTTTGAAACAGAAATGCATACTTTAAACCTAGATAGATTCATCTGGCAATTCCCTTTCTCAAGCGAAGACTAATTTTAGAATTTGTGGTCTTTTTAAAATTTTATAAATCCAAATTCTTATGTGTTTAAAATATGCTTAAACTTACGGGACATTGATATTATTCTTTGAAAAATGAACTTAAATGAAAGTCAGGTTTTTTATAGACATGGAAACTTTGTTCTAACATATTATTTTAATACCATCATCTCATTGGCTTAGCATAATTTATGTGGTTAATTCATAGTTGGATTACAGTGTTACCAGTCACAATGTAGAATTAGAATAAAAGATCACTGTTTAGAGAGTATTTTTTGATTGGTTTAACTTTGTACACTAAATATATTTATAATAGATAATGTTCTGTTTTGACTTTTTAATTTTAATTTCCTACTATGTTCATATAATAAACATTCTAGTTTCAGACCATTATTAAAGAAAGTGAATATAAACTTTATATGTATGTTTGCATTTTTTTATAG
Seq C2 exon
TCAGAAACAAATTTAAGTAAAGAAATGGAATCTGTAATGAAAGATATAAAAAATACCACTCAGAAGAAATATAGAGACTATAGCAAGACCCCGGGCTCACCAGACAATGATTTTCTCTTTATGTACTCTGTTGCTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144357:ENST00000272793:28
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.168 A=NA C2=0.387
Domain overlap (PFAM):
C1:
PF136391=zf-RING_2=PD(35.1=29.9)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGACCAGGTTCTTCAGGGCT
R:
AGCAACAGAGTACATAAAGAGAAAAT
Band lengths:
335-1948
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains