HsaINT0177874 @ hg19
Intron Retention
Gene
ENSG00000107731 | UNC5B
Description
unc-5 homolog B (C. elegans) [Source:HGNC Symbol;Acc:12568]
Coordinates
chr10:73048715-73050866:+
Coord C1 exon
chr10:73048715-73048747
Coord A exon
chr10:73048748-73050671
Coord C2 exon
chr10:73050672-73050866
Length
1924 bp
Sequences
Splice sites
5' ss Seq
ACCGTAAGT
5' ss Score
10.43
3' ss Seq
TGGTCCTCCTGTCCCCGCAGTGC
3' ss Score
10.63
Exon sequences
Seq C1 exon
ATAAGAAAACTCTAAGCGACCCCAACAGCCACC
Seq A exon
GTAAGTCCCATTTCATGGCTGTCCTCTTTCCTCTGGGGGATCCCTGGTTCTCTTTGGCTGGCTTTTCCCGGGATCAGGGTGCAGGGCAGGGAGAGCTGAAGGTGCCTACCCACCCCCCACGGGATCATCTACACCTGACACTGCATGTGTCTGCATCTCCATCACCGGCAGACAGGCAAACCCTTGGCTGACAGAAAAGAAAGGCCTTAGGGCACCCTACTGAGCCTCCTCTCATAAGAGGGGAAACTGAGTCACAGAGAGAGGAAGGGACTTGGCCAGAGACACAGGCAAGAAATAGTAGAGCCAAGATTTGAACCCAAATATTTTTATAGCCAAAGCTGTTGTTCTTAACCATATGCCCTTGGCCCTCCTCTCTGGGCCAAGGCCGGGACATCACCACTCCAGTCCCCCCTCATGCCCCTTGCTGTACCTCTCTGCCCCAGCAGCTGGGCCAAGCCTCCCAAATTGTCTCTGTTGCCCGCTGCCCTGCGTCAGCTCTGGAGGGCTCACCCTCCAGCCCCAGAGGCTGCGCCACCACTGCAATCATATCAGAGCAGCAAAGCCACTTGAGCAGGTTGGCCCATGGTAATTAAACCACAATTTCCAGTTAGTTCTGGAATCATAAAATCAGTGAGGCCCTCGGCCGAGCTCACTGGGGGTCGGGCTGGGGATGATTCAAGTGTAAGTCACCAGGCAAGTGGCCCCAGTGTCAGTGAAGGCATTAGGAGGCAGAGCCAAGCTGGGGGAACCATTTCTCTGCTGAACCAGGAGCCCAGCCCTGAGGGGTCCTCTGGGGAGCCCAAGAGTGAGGGCTGCTGAGGAGAGATACAGGGGGACAGAAGTCGGAAGTGGGCAGACATCCGGGGCTGGGAGCCATGCCCTGCCTTGCTGAAAGCCTTAGGCTGACGCCAAGTGCAGGGTGTGGAGGACTCCAGGCAGAGGAAGCAGGGCTACTTCTCTGAGGGCCCCCCAGGGAGGAAGTGCGTGGACAGGTGCTTCCTGGAGCTCCCAAAGGAAGCAAGGGGAAGAGCAGCCATCTTGGCCGCCATTTTTGCTCTCCCTGAACTGCCCAGTGTGAAAGCCGTTCAAACTTATACTTAGCTTAATTAAAATTAAATAAATTTTTAAATTCAGTTCCTCAGCGGTACTGGCTACATTTGAGTTGTTCAGGAGCCATATGTGACTAGTGGCTGCATACGGGACAGTGCAGCCATAGGATTTTCTACCACTGTAGAAAGCTCCACCAGACAACCCTACTTCAGACCCTGCCACTTTGACCTTGAGGCTTCCCGCCTGGCCATGTTTGCCTGGGGGAGGAAAGTGTAGCCGTGGGTTGCCTCCCTGGGCCCATCCTTCTTCCCACATGCTCACCTCTTCTCCACCGCATTGTTGTGCATCTCATTCCACTTCTTCAGCTCCCCGTCCCTCCACTTCCCACCCTCAGAGCATGGAATGGAAGAAGAGTTCAGAACAGCTACTTACAAAGATAACAGAGCCAGAAGACCTTATCTACATACAAAGATAACAGAGCCAGGACCTTTGGTCCTCTGGAAATTGCTACAGACTCAGAGGTTTCAGCCCCAGCACTCACAGGGCAAATTATGTAGCCCCAGTGACTCTGAGCCACAGACCCTGTCTCATCAGCAGCAAGCAATGAATTAACACATGGCATGAACATGTTTGTTCTTTTGTTTCTCATGCCACAACTAGGAGGGCAGTAAGGCAGGGACTTCGAGCCCATTTTACCGATAGAGAGGTTCAAGGCTAGCCCGAGGTTGCCAGCCTGTGTAGGCAGGGCTCAGACTGGAACTCAGCACCGGGCCGGTTGGCCCTGGGCCCTGCCCTTTCCAGGGACCCAGGGCCTCCCTGATTGCCCCAGGGCCTGGTCTCTGCTGCCCCTTATGTGGTCCTCCTGTCCCCGCAG
Seq C2 exon
TGCTGGAGGCCTCAGGGGATGCGGCGCTGTATGCGGGGCTCGTGGTGGCCATCTTCGTGGTCGTGGCAATCCTCATGGCGGTGGGGGTGGTGGTGTACCGCCGCAACTGCCGTGACTTCGACACAGACATCACTGACTCATCTGCTGCCCTGACTGGTGGTTTCCACCCCGTCAACTTTAAGACGGCAAGGCCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000107731-UNC5B:NM_170744:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.167 A=NA C2=0.015
Domain overlap (PFAM):
C1:
PF150281=PTCRA=FE(9.6=100)
A:
NA
C2:
PF150281=PTCRA=PD(21.9=37.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAAAACTCTAAGCGACCCCA
R:
GGCCTTGCCGTCTTAAAGTTG
Band lengths:
223-2147
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)