Special

MmuEX0004909 @ mm9

Exon Skipping

Gene
ENSMUSG00000069601 | Ank3
Description
ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]
Coordinates
chr10:69284956-69287164:+
Coord C1 exon
chr10:69284956-69285141
Coord A exon
chr10:69285826-69285849
Coord C2 exon
chr10:69287066-69287164
Length
24 bp
Sequences
Splice sites
3' ss Seq
CTCCCAATGTGTTAACCTAGATG
3' ss Score
4.99
5' ss Seq
GAGGTATAT
5' ss Score
7.3
Exon sequences
Seq C1 exon
GACGGCTTCACGCCATTGGCCGTGGCTCTGCAACAAGGTCATGACCAAGTCGTGTCCCTCCTGCTCGAGAACGACACGAAGGGAAAAGTGCGCCTCCCAGCCCTCCACATCGCAGCCCGGAAAGACGACACCAAGGCAGCAGCTCTGCTCCTGCAGAATGACACAAACGCGGACGTGGAGTCAAAG
Seq A exon
ATGGTGGTGAATAGAGCAACTGAG
Seq C2 exon
AGTGGCTTCACCCCGCTCCACATAGCTGCCCACTATGGGAACATCAATGTGGCCACGTTGCTGTTAAACCGAGCGGCTGCTGTGGACTTCACCGCACGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000069601-'7-10,'7-9,8-10
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (No Ref)





Show structural model

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.018 A=0.125 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF127962=Ank_2=PD(44.9=50.0),PF136501=Asp_protease_2=PD(68.2=93.5),PF127962=Ank_2=PU(29.0=43.5)

							
A:
PF127962=Ank_2=FE(6.9=100)

							
C2:
PF136371=Ank_4=PD(38.9=63.6),PF127962=Ank_2=PU(14.3=33.3)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000090090f5394A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000090090f5603A





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000053138, ENSMUSP00000061698, ENSMUSP00000090087, ENSMUSP00000090088, ENSMUSP00000090090, ENSMUSP00000090090f5390A, ENSMUSP00000090090f5391A, ENSMUSP00000090090f5392A, ENSMUSP00000090090f5393A, ENSMUSP00000090090f6290A, ENSMUSP00000090090f6291A
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr10:60263126-60263149 
ALTERNATIVE
HsaEX1003668
(ANK3)
Human
(hg19)
chr10:62022884-62022907 
Rat
(rn6)
chr20:20274773-20274796 
ALTERNATIVE
RnoEX0009382
(Ank3)
Cow
(bosTau6)
chr28:16055793-16055816 
ALTERNATIVE
BtaEX0003422
(ANK3)
Chicken
(galGal4)
chr6:8383735-8383758 
ALTERNATIVE
GgaEX0004069
(chAnk3)
Chicken
(galGal3)
chr6:10044645-10044668 
LOW PSI
GgaEX0004069
(Q90717_CHICK)
Zebrafish
(danRer10)
chr12:7756234-7756257 
ALTERNATIVE
DreEX0013149
(ank3b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CTGCAGAATGACACAAACGCG

				
R: 
TAACAGCAACGTGGCCACATT

				
Band lengths: 
102-126

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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