Special

MmuEX0004913 @ mm9

Exon Skipping

Gene
ENSMUSG00000069601 | Ank3
Description
ankyrin 3, epithelial [Source:MGI Symbol;Acc:MGI:88026]
Coordinates
chr10:69340578-69395244:+
Coord C1 exon
chr10:69340578-69340676
Coord A exon
chr10:69342641-69342739
Coord C2 exon
chr10:69395142-69395244
Length
99 bp
Sequences
Splice sites
3' ss Seq
CTTCCACTTACGTTCCCCAGAGA
3' ss Score
7.18
5' ss Seq
AAGGTAAGG
5' ss Score
10.51
Exon sequences
Seq C1 exon
TCGGGCCTTACCCCAATCCATGTTGCTGCCTTCATGGGACATGTAAATATCGTGTCACAGCTAATGCATCATGGAGCCTCCCCAAACACCACCAATGTG
Seq A exon
AGAGGAGAGACGGCATTGCATATGGCGGCTCGGTCCGGACAAGCAGAAGTGGTGCGGTATCTGGTCCAAGATGGGGCTCAGGTAGAAGCAAAAGCTAAG
Seq C2 exon
CCTCCGCTCCTTCAGTTCGGATAGGTCCTACACCTTGAACAGAAGCTCCTACGCAAGGGACAGCATGATGATAGAGGAACTTCTGGTACCATCCAAAGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000069601_MULTIEX1-12/25=11-25
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.303 A=0.273 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF136371=Ank_4=PU(57.4=93.9)

							
A:
PF136371=Ank_4=PD(38.9=63.6),PF127962=Ank_2=PU(8.3=18.2)

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000090090f5603A





     
                   









    
Main Skipping Isoform:
ENSMUSP00000090089





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000061698, ENSMUSP00000090087, ENSMUSP00000090088, ENSMUSP00000090090, ENSMUSP00000090090f5390A, ENSMUSP00000090090f5391A, ENSMUSP00000090090f5392A, ENSMUSP00000090090f5393A, ENSMUSP00000090090f5394A, ENSMUSP00000090090f6290A, ENSMUSP00000090090f6291A
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr10:60200129-60200227 
ALTERNATIVE
HsaEX0004149
(ANK3)
Human
(hg19)
chr10:61959887-61959985 
HIGH PSI
HsaEX0004149
(ANK3)
Rat
(rn6)
chr20:20330144-20330242 
HIGH PSI
RnoEX6062481
(Ank3)
Cow
(bosTau6)
chr28:15995992-15996090 
HIGH PSI
BtaEX6105140
(ANK3)
Chicken
(galGal4)
chr6:8413520-8413618 
HIGH PSI
GgaEX1065942
(chAnk3)
Chicken
(galGal3)
chr6:10074430-10074528 
HIGH PSI
GgaEX1065942
(Q90717_CHICK)
Zebrafish
(danRer10)
chr12:7731245-7731343 
HIGH PSI
DreEX0013131
(ank3b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GGCCTTACCCCAATCCATGTT

				
R: 
ATCATCATGCTGTCCCTTGCG

				
Band lengths: 
168-267

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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