MmuEX0008846 @ mm10
Exon Skipping
Gene
ENSMUSG00000017412 | Cacnb4
Description
calcium channel, voltage-dependent, beta 4 subunit [Source:MGI Symbol;Acc:MGI:103301]
Coordinates
chr2:52467244-52474985:-
Coord C1 exon
chr2:52474863-52474985
Coord A exon
chr2:52469477-52469607
Coord C2 exon
chr2:52467244-52467320
Length
131 bp
Sequences
Splice sites
3' ss Seq
CTTTCCTCTCTGCTTTCCAGAAA
3' ss Score
10.56
5' ss Seq
CGGGTAACA
5' ss Score
5.3
Exon sequences
Seq C1 exon
TCCAAACCTGTAGCTTTTGCGGTGAAAACGAACGTGAGCTACTGTGGTGCCCTGGACGAAGATGTGCCCGTTCCCAGCACAGCCATCTCCTTTGACGCCAAGGACTTTCTTCACATTAAAGAG
Seq A exon
AAATATAACAATGATTGGTGGATAGGAAGACTGGTAAAAGAGGGCTGTGAGATTGGCTTCATCCCAAGTCCACTGCGCTTGGAGAATATTCGGATTCAACAGGAACAGAAAAGAGGCCGTTTTCATGGCGG
Seq C2 exon
GAAATCGAGTGGAAACTCTTCCTCCAGTCTGGGAGAAATGGTATCAGGAACATTCCGAGCAACTCCCACAACAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000017412_MULTIEX1-1/5=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.223 C2=0.889
Domain overlap (PFAM):
C1:
PF120523=VGCC_beta4Aa_N=PD(2.4=2.4),PF0001823=SH3_1=PU(44.2=46.3)
A:
PF0001823=SH3_1=PD(51.2=50.0)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTTTGCGGTGAAAACGAACGT
R:
TGTTGTTGTGGGAGTTGCTCG
Band lengths:
186-317
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types