Special

MmuEX0014977 @ mm10

Exon Skipping

Gene
ENSMUSG00000033987 | Dnah17
Description
dynein, axonemal, heavy chain 17 [Source:MGI Symbol;Acc:MGI:1917176]
Coordinates
chr11:118034243-118038342:-
Coord C1 exon
chr11:118038149-118038342
Coord A exon
chr11:118036332-118036480
Coord C2 exon
chr11:118034243-118034376
Length
149 bp
Sequences
Splice sites
3' ss Seq
AGAGCCTGTGTTCCCCTCAGGAA
3' ss Score
8.07
5' ss Seq
TCGGTAGGC
5' ss Score
7.75
Exon sequences
Seq C1 exon
GCCCTGTCGGAGATGGATGAGTTCAAGAACTTGGACAGTGACATTGAGGGCTCGGCCAAGAGGTGGAAAAAGCTGGTGGAGTCGGAAGCGCCCGAGAAAGAGATCTTCCCCAAAGAATGGAAGAACAAGACCGCCCTGCAGAAGCTGTGCATGGTGCGCTGCATGAGGCCGGACCGCATGACCTATGCTGTCAA
Seq A exon
GAATTTTGTGGAAGAGAAGATGGGCAGTAAGTTCGTTGAAGGCCGGAGCGTGGAGTTCTCCAAGTCCTACAAAGAGAGCAGCCCTTCCACACCAATCTTCTTCATCCTTTCCCCCGGGGTTGACCCCCTCAAAGACGTGGAGGCCCTCG
Seq C2 exon
GGAAAAAACTGGGATTTACCATAGACAATGGGAAACTCCACAACGTGTCCCTGGGGCAAGGACAAGAGGTGGTAGCTGAGAACGCGCTGGATGTGGCTGCCGAAAAGGGACACTGGGTCATTCTGCAGGTGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000033987-'87-94,'87-93,88-94
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0302810=Dynein_heavy=FE(24.2=100)

							
A:
PF0302810=Dynein_heavy=FE(18.9=100)

							
C2:
PF0302810=Dynein_heavy=FE(16.6=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000101915





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000081864, ENSMUSP00000120542
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr17:78441051-78441199 
ALTERNATIVE
HsaEX0020177
(DNAH17)
Human
(hg19)
chr17:76437133-76437281 
ALTERNATIVE
HsaEX0020177
(DNAH17)
Rat
(rn6)
chr10:107044707-107044855 
ALTERNATIVE
RnoEX0028496
(Dnah17)
Cow
(bosTau6)
chr19:54394207-54394355 
HIGH PSI
BtaEX6090358
(DNAH17)
Chicken
(galGal4)
chr18:10093409-10093557 
HIGH PSI
GgaEX6016561
(DNAH17)
Chicken
(galGal3)
chr18:9765359-9765507 
HIGH PSI
GgaEX6016561
(DNAH17)
Zebrafish
(danRer10)
chr6:10363866-10364014 
DreEX6020703
(dnah9l)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CCCTGTCGGAGATGGATGAGT

				
R: 
CAGGGACACGTTGTGGAGTTT

				
Band lengths: 
246-395

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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