Special

MmuEX0015121 @ mm9

Exon Skipping

Gene
ENSMUSG00000056752 | Dnahc9
Description
dynein, axonemal, heavy chain 9 [Source:MGI Symbol;Acc:MGI:1289279]
Coordinates
chr11:65668689-65684570:-
Coord C1 exon
chr11:65684422-65684570
Coord A exon
chr11:65672909-65673036
Coord C2 exon
chr11:65668689-65668916
Length
128 bp
Sequences
Splice sites
3' ss Seq
AAATTCCATGCTTATTTTAGGAA
3' ss Score
6.5
5' ss Seq
CAGGTATAG
5' ss Score
8.73
Exon sequences
Seq C1 exon
AGATTTTGTTGAGGAGAAGTTGGGAAGCAAATACGTGATGGGAAGAGCACTCGATTTTGTAACCTCATTTGAAGAGTCAGGACCAGCCACTCCCATGTTTTTCATCCTGTCTCCAGGGGTGGATCCACTGAAGGATGTGGAAAATCAAG
Seq A exon
GAAAGAAACTTGGATATACATTCAACAATCGGAACTTCCACAACGTGTCCCTAGGGCAAGGACAAGAGGTAGTTGCTGAGGCTGCACTGGACTTGGCTGCTAAGAAGGGTCACTGGGTGATTCTGCAG
Seq C2 exon
AACATCCACCTGGTGGCCAAGTGGCTCAGTACCCTGGAGAAGAAACTGGAGGAGCTCAGCGAGGAAAGTCACCCAGACTTCAGGGTCTTCATCAGCGCAGAGCCTGCACCCTCCCCTGAGGGCCACATCATTCCCCAGGGCATTCTGGAAAACTCCATTAAGATCACCAATGAGCCTCCCACAGGCATGCACGCCAACTTACACAAAGCCCTGGACAACTTCACTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000056752_MULTIEX1-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.118
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0302810=Dynein_heavy=FE(27.2=100)

							
A:
PF0302810=Dynein_heavy=FE(23.9=100),PF0302810=Dynein_heavy=PU(0.1=0.0)

							
C2:
PF0302810=Dynein_heavy=FE(10.7=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000079494





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000116499
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr17:11923814-11923941 
HIGH PSI
HsaEX6021117
(DNAH9)
Human
(hg19)
chr17:11827131-11827258 
HIGH PSI
HsaEX6021117
(DNAH9)
Rat
(rn6)
chr10:52375381-52375508 
ALTERNATIVE
RnoEX0028669
(Dnah9)
Cow
(bosTau6)
chr19:31223662-31223789 
HIGH PSI
BtaEX6087238
(DNAH9)
Chicken
(galGal4)
chr18:10093686-10093813 
HIGH PSI
GgaEX6016560
(DNAH17)
Chicken
(galGal3)
chr18:1155760-1155887 
HIGH PSI
GgaEX1020256
(DNAH9)
Zebrafish
(danRer10)
chr6:10363203-10363330 
DreEX0027520
(dnah9l)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GACCAGCCACTCCCATGTTTT

				
R: 
TGGGAGGCTCATTGGTGATCT

				
Band lengths: 
250-378

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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