Special

MmuEX0018615 @ mm10

Exon Skipping

Description
fibroblast activation protein [Source:MGI Symbol;Acc:MGI:109608]
Coordinates
chr2:62548570-62573523:-
Coord C1 exon
chr2:62573439-62573523
Coord A exon
chr2:62554745-62554839
Coord C2 exon
chr2:62548570-62548642
Length
95 bp
Sequences
Splice sites
3' ss Seq
GCTTTCTTTTGTGTTTAAAGAAC
3' ss Score
6.32
5' ss Seq
ATGGTATGT
5' ss Score
8.35
Exon sequences
Seq C1 exon
ACATGGCTGAAAACTGTCTTTGGAGTTACCACCCTGGCTGCGCTTGCTTTAGTGGTGATATGCATTGTCTTACGTCCCTCAAGAG
Seq A exon
AACAAGAATATCTTCATCAATCTGAGGATGATAACATAGTATTTTATAATATTGAAACAAGAGAATCATATATCATTTTGAGTAATAGCACCATG
Seq C2 exon
GGAATTTGTAAGAGGATACGAGCTCCCTCGTCCAATTCAGTATCTATGCTGGTCGCCTGTTGGGAGTAAATTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000000392_MULTIEX2-2/4=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
NO
A:
PF0093016=DPPIV_N=PU(3.5=40.6)
C2:
PF0093016=DPPIV_N=FE(6.5=100)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
(FAP)
Chicken
(galGal3)
HIGH PSI
(FAP)
Zebrafish
(danRer10)
HIGH PSI
Zebrafish
(danRer10)
HIGH PSI
(fap)
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCTGAAAACTGTCTTTGGAGT
R:
TTTACTCCCAACAGGCGACCA
Band lengths:
152-247
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types