Special

MmuEX0024734 @ mm10

Exon Skipping

Gene
ENSMUSG00000030102 | Itpr1
Description
inositol 1,4,5-trisphosphate receptor 1 [Source:MGI Symbol;Acc:MGI:96623]
Coordinates
chr6:108417889-108431496:+
Coord C1 exon
chr6:108417889-108418000
Coord A exon
chr6:108423333-108423365
Coord C2 exon
chr6:108431461-108431496
Length
33 bp
Sequences
Splice sites
3' ss Seq
CCTCCTTTCTTCTTTTCCAGCAA
3' ss Score
11.6
5' ss Seq
GAGGTCCTA
5' ss Score
-2.92
Exon sequences
Seq C1 exon
GCTAATAAAACATACCAAGCAACTGCTGGAGGAGAATGAAGAGAAACTATGCATTAAAGTCTTACAGACCCTCAGGGAAATGATGACCAAAGACAGAGGCTATGGAGAGAAG
Seq A exon
CAAATTTCCATTGATGAATCGGAAAATGCCGAG
Seq C2 exon
CTGCCACAGGCACCGGAAGCTGAGAACTCCACAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030102-'86-74,'86-73,88-74
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.187 A=1.000 C2=1.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000032192





     
                   









    
Main Skipping Isoform:
ENSMUSP00000145177





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000144880
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm9




Conservation


Human
(hg38)
chr3:4717367-4717399 
ALTERNATIVE
HsaEX0032565
(ITPR1)
Human
(hg19)
chr3:4759051-4759083 
ALTERNATIVE
HsaEX0032565
(ITPR1)
Rat
(rn6)
chr4:140455847-140455879 
ALTERNATIVE
RnoEX0045397
(Itpr1)
Cow
(bosTau6)
chr22:21741094-21741126 
ALTERNATIVE
BtaEX0018597
(ITPR1)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
chr12:19110179-19110208 
ALTERNATIVE
GgaEX0027288
(Q9DEX2_CHICK)
Zebrafish
(danRer10)
chr11:35636928-35636963 
ALTERNATIVE
DreEX0040341
(itpr1b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GCAACTGCTGGAGGAGAATGA

				
R: 
CTGTGGAGTTCTCAGCTTCCG

				
Band lengths: 
128-161

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"