Special

MmuEX0024735 @ mm10

Exon Skipping

Gene
ENSMUSG00000030102 | Itpr1
Description
inositol 1,4,5-trisphosphate receptor 1 [Source:MGI Symbol;Acc:MGI:96623]
Coordinates
chr6:108423333-108438432:+
Coord C1 exon
chr6:108423333-108423365
Coord A exon
chr6:108431461-108431496
Coord C2 exon
chr6:108438300-108438432
Length
36 bp
Sequences
Splice sites
3' ss Seq
TTCGTTTTACTCCCAACTAGCTG
3' ss Score
5.18
5' ss Seq
GAGGTGTGT
5' ss Score
6.14
Exon sequences
Seq C1 exon
CAAATTTCCATTGATGAATCGGAAAATGCCGAG
Seq A exon
CTGCCACAGGCACCGGAAGCTGAGAACTCCACAGAG
Seq C2 exon
GGTGAGGCACTCCGACAAATTTTGGTCAACCGTTACTATGGAAACATCAGACCTTCAGGAAGAAGAGAGAGCCTTACCAGCTTTGGCAATGGCCCACTATCACCAGGAGGACCCAGCAAGCCTGGTGGAGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030102_MULTIEX1-40/59=39-42
Average complexity
C3
Mappability confidence:
97%=98=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=1.000 A=1.000 C2=0.542
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000032192





     
                   









    
Main Skipping Isoform:
ENSMUSP00000145522





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000144880, ENSMUSP00000145177
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm9




Conservation


Human
(hg38)
chr3:4725546-4725581 
ALTERNATIVE
HsaEX0032566
(ITPR1)
Human
(hg19)
chr3:4767230-4767265 
ALTERNATIVE
HsaEX0032566
(ITPR1)
Rat
(rn6)
chr4:140463454-140463489 
ALTERNATIVE
RnoEX0045415
(Itpr1)
Cow
(bosTau6)
chr22:21733145-21733180 
ALTERNATIVE
BtaEX0018598
(ITPR1)
Chicken
(galGal4)
chr12:18474504-18474539 
ALTERNATIVE
GgaEX0027289
(ITPR1)
Chicken
(galGal3)
chr12:19118814-19118849 
ALTERNATIVE
GgaEX0027289
(Q9DEX2_CHICK)
Zebrafish
(danRer10)
chr11:35625862-35625897 
ALTERNATIVE
DreEX0040342
(itpr1b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TCCATTGATGAATCGGAAAATGCC

				
R: 
TTGCCAAAGCTGGTAAGGCTC

				
Band lengths: 
116-152

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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