Special

MmuEX6006000 @ mm10

Exon Skipping

Gene
ENSMUSG00000030102 | Itpr1
Description
inositol 1,4,5-trisphosphate receptor 1 [Source:MGI Symbol;Acc:MGI:96623]
Coordinates
chr6:108432646-108471203:+
Coord C1 exon
chr6:108432646-108432696
Coord A exon
chr6:108438300-108438432
Coord C2 exon
chr6:108471023-108471203
Length
133 bp
Sequences
Splice sites
3' ss Seq
CATTATCCTGTTTAAATTAGGGT
3' ss Score
7.31
5' ss Seq
GAGGTAGGC
5' ss Score
8.99
Exon sequences
Seq C1 exon
CAGGAGCTTGAACCAAGTCCACCCCTGAGGCAACTGGAAGACCATAAAAGG
Seq A exon
GGTGAGGCACTCCGACAAATTTTGGTCAACCGTTACTATGGAAACATCAGACCTTCAGGAAGAAGAGAGAGCCTTACCAGCTTTGGCAATGGCCCACTATCACCAGGAGGACCCAGCAAGCCTGGTGGAGGAG
Seq C2 exon
CACTCGTTTTTCTGCCGGCTGACAGAAGATAAGAAATCAGAGAAGTTCTTCAAGGTTTTTTACGATCGAATGAAGGTGGCCCAGCAGGAAATCAAGGCGACAGTGACAGTGAACACCAGCGACTTGGGAAACAAAAAGAAAGATGATGAAGTGGACAGGGATGCCCCGTCTCGGAAGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030102_MULTIEX1-42/59=41-44
Average complexity
C3
Mappability confidence:
97%=95=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=1.000 A=0.542 C2=0.391
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000032192





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000144880, ENSMUSP00000145177, ENSMUSP00000145339, ENSMUSP00000145522
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm9




Conservation


Human
(hg38)
chr3:4733088-4733220 
HIGH PSI
HsaEX1018098
(ITPR1)
Human
(hg19)
chr3:4774772-4774904 
Rat
(rn6)
chr4:140470174-140470306 
HIGH PSI
RnoEX6014527
(Itpr1)
Cow
(bosTau6)
chr22:21726642-21726774 
HIGH PSI
BtaEX0018600
(ITPR1)
Chicken
(galGal4)
chr12:18479067-18479199 
ALTERNATIVE
GgaEX0012010
(ITPR1)
Chicken
(galGal3)
chr12:19123377-19123509 
ALTERNATIVE
GgaEX0012010
(Q9DEX2_CHICK)
Zebrafish
(danRer10)
chr11:35617995-35618124 
HIGH PSI
DreEX6092763
(itpr1b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GAGCTTGAACCAAGTCCACCC

				
R: 
GGCATCCCTGTCCACTTCATC

				
Band lengths: 
213-346

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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