Special

MmuEX0026041 @ mm10

Exon Skipping

Gene
ENSMUSG00000024421 | Lama3
Description
laminin, alpha 3 [Source:MGI Symbol;Acc:MGI:99909]
Coordinates
chr18:12481943-12491612:+
Coord C1 exon
chr18:12481943-12482147
Coord A exon
chr18:12490919-12491063
Coord C2 exon
chr18:12491472-12491612
Length
145 bp
Sequences
Splice sites
3' ss Seq
GTTCCTTTATCCCTGTACAGGTG
3' ss Score
9.63
5' ss Seq
AAGGTGAGA
5' ss Score
8.68
Exon sequences
Seq C1 exon
CTTGTAATTGTGGCAGACGCCTTTGTGAAGAGGTGACAGGGAAGTGTCTCTGCCCACCCCACACAGTCAGGCCTCAGTGTGAGGTCTGTGAGATGAATTCCTTCAACTTTCACCCTGTGGCTGGCTGTGACGTCTGCAACTGCTCCAGGAAGGGCACCATTGAGGCGGCCGTCTCTGAGTGTGACAGGGACAGCGGGCAGTGCAG
Seq A exon
GTGCAAGCCTAGAGTCACAGGGCAGCAGTGTGACAAGTGTGCTCCTGGCTTCTACCAGTTCCCTGAGTGTGTCCCCTGCAGCTGTAACAGAGATGGGACTGAGCCCAGCGTATGTGACCCAGAGACTGGGGCTTGCATGTGCAAG
Seq C2 exon
GAAAATGTAGAGGGCCCCCAATGTCAACTGTGTCGAGAAGGATCATTCTACCTGGACCCAACAAACCCAAAGGGTTGTACCAAGTGCTTCTGTTTTGGAGTGAATACTGACTGTCAGAGTTCGCATAAGCAACGAGCTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024421-'41-41,'41-40,42-41
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0005319=Laminin_EGF=PD(6.1=4.3),PF0005319=Laminin_EGF=PU(46.9=33.3)

							
A:
PF0005319=Laminin_EGF=PD(51.0=51.0),PF0005319=Laminin_EGF=PU(44.9=44.9)

							
C2:
PF0005319=Laminin_EGF=PD(51.0=53.2)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000089703





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm9




Conservation


Human
(hg38)
chr18:23857844-23857988 
HIGH PSI
HsaEX6038394
(LAMA3)
Human
(hg19)
chr18:21437808-21437952 
HIGH PSI
HsaEX6038394
(LAMA3)
Rat
(rn6)
chr18:3849448-3849592 
HIGH PSI
RnoEX6058078
(AABR07031193.1)
Cow
(bosTau6)
chr24:33177109-33177253 
HIGH PSI
BtaEX6091844
(LAMA3)
Chicken
(galGal4)
chr2:102848754-102848898 
HIGH PSI
GgaEX1032799
(LAMA3)
Chicken
(galGal3)
chr2:106344087-106344231 
HIGH PSI
GgaEX1032799
(LAMA3)
Zebrafish
(danRer10)
chr23:9696766-9696910 
HIGH PSI
DreEX6079188
(lama5)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ACGCCTTTGTGAAGAGGTGAC

				
R: 
TGGGTTTGTTGGGTCCAGGTA

				
Band lengths: 
258-403

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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