MmuEX0028277 @ mm10
Exon Skipping
Gene
ENSMUSG00000039842 | Mcph1
Description
microcephaly, primary autosomal recessive 1 [Source:MGI Symbol;Acc:MGI:2443308]
Coordinates
chr8:18622607-18627240:+
Coord C1 exon
chr8:18622607-18622694
Coord A exon
chr8:18625560-18625674
Coord C2 exon
chr8:18627118-18627240
Length
115 bp
Sequences
Splice sites
3' ss Seq
TTTATAACCTTTTTGCCTAGCAC
3' ss Score
4.45
5' ss Seq
TAGGTAAGC
5' ss Score
8.89
Exon sequences
Seq C1 exon
ATGCAGGATGGCTGGAGCACTTGTTGATGAGTCTTTGTTCCCTGCAGTGAATACCGATGAACATCTACCAAACTTAAGTAGAAAAAAA
Seq A exon
CACAAATGTATGCAACCCAAAGATTTTATTCTTAAAACACCAGAAAATGACAAAAGACTTCAAAAGAAATTTGAGAAAATGGCTGAAGAGCTACAAAGGCAAAAGGCAGCTCTAG
Seq C2 exon
ATGATGACGTTCCTGTCCTCCTGTTTGAGTCCCCTCGCTCACTGGTGTACAGCTCCCCAGTGAATGTGATGAAGAGGAGACTGCAGGATATGAAGGAGAAGAGGGAGAACCTTTCCCCTACCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000039842_MULTIEX1-3/12=2-4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.175 A=0.373 C2=0.336
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGATGGCTGGAGCACTTGTT
R:
GGGGAAAGGTTCTCCCTCTTCT
Band lengths:
202-317
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types