MmuEX0028768 @ mm10
Exon Skipping
Gene
ENSMUSG00000041975 | Mettl8
Description
methyltransferase like 8 [Source:MGI Symbol;Acc:MGI:2385142]
Coordinates
chr2:70973253-70982195:-
Coord C1 exon
chr2:70981855-70982195
Coord A exon
chr2:70980377-70980426
Coord C2 exon
chr2:70973253-70973392
Length
50 bp
Sequences
Splice sites
3' ss Seq
TTGTTTATTCTCAATTTTAGGTT
3' ss Score
12.25
5' ss Seq
GCAGTGAGT
5' ss Score
7.39
Exon sequences
Seq C1 exon
TTAAGTTTGAAAGTGACGCTAACAAATACTGGGATATATTTTACCAGACCCATAAGAATAAGTTTTTCAAGAATCGTAATTGGCTGTTGAGGGAATTTCCTGAAATCCTTCCTGTTAATCAAAACACTAAAGAGAAAGTGGGAGAATCATCCTGGGATCAAGTCGGAAGCAGCATCTCTAGGACACAAGGAACAGAAACCCATTGTCAAGAGAGTTTTGTCTCGCCAGAACCTGGGAGCAGAGGACGGTCTGCTCCTGACCCCGACTTGGAAGAATACAGCAAAGGACCTGGGAAGACAGAGCCGTTTCCTGGTAGCAATGCCACTTTTCGAATACTAGAG
Seq A exon
GTTGGCTGTGGTGCTGGAAATAGCGTGTTTCCAATCCTGAACACCTTGCA
Seq C2 exon
TCCCACGAGTCCTACAGCGAGGCCCAGTGTTCTGCCTTTATTCATGACGTGTGTGACGACGGCTTAGCCTACCCTTTCCCAGATGGGATCCTGGATGTCGTTCTCCTTGTCTTTGTGCTCTCATCTATCCACCCTGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000041975_MULTIEX3-2/4=1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.529 A=0.088 C2=0.025
Domain overlap (PFAM):
C1:
PF134891=Methyltransf_23=PU(15.8=26.3)
A:
PF082417=Methyltransf_11=FE(17.6=100)
C2:
PF082417=Methyltransf_11=PU(67.7=95.7)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGACAGAGCCGTTTCCTGG
R:
CCATCTGGGAAAGGGTAGGCT
Band lengths:
135-185
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types