Special

MmuEX0028769 @ mm10

Exon Skipping

Gene
Description
methyltransferase like 8 [Source:MGI Symbol;Acc:MGI:2385142]
Coordinates
chr2:70973253-70980426:-
Coord C1 exon
chr2:70980377-70980426
Coord A exon
chr2:70976074-70976137
Coord C2 exon
chr2:70973253-70973392
Length
64 bp
Sequences
Splice sites
3' ss Seq
TGTCGTTTCTATTTACATAGGAA
3' ss Score
8.36
5' ss Seq
AAGGTATGC
5' ss Score
9.55
Exon sequences
Seq C1 exon
GTTGGCTGTGGTGCTGGAAATAGCGTGTTTCCAATCCTGAACACCTTGCA
Seq A exon
GAACATTCCAGGATCCTTTCTCTACTGCTGCGACTTTGCCTCTGAAGCTGTGGAACTTGTAAAG
Seq C2 exon
TCCCACGAGTCCTACAGCGAGGCCCAGTGTTCTGCCTTTATTCATGACGTGTGTGACGACGGCTTAGCCTACCCTTTCCCAGATGGGATCCTGGATGTCGTTCTCCTTGTCTTTGTGCTCTCATCTATCCACCCTGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000041975_MULTIEX3-4/4=2-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

Show structural model
Features
Disorder rate (Iupred):
  C1=0.088 A=0.000 C2=0.025
Domain overlap (PFAM):

C1:
PF082417=Methyltransf_11=FE(17.6=100)
A:
PF134891=Methyltransf_23=FE(11.1=100)
C2:
PF082417=Methyltransf_11=PU(67.7=95.7)


Main Inclusion Isoform:


Main Skipping Isoform:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTGGTGCTGGAAATAGCGTG
R:
AGAACGACATCCAGGATCCCA
Band lengths:
148-212
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types