MmuEX0041257 @ mm9
Exon Skipping
Gene
ENSMUSG00000064329 | Scn1a
Description
sodium channel, voltage-gated, type I, alpha [Source:MGI Symbol;Acc:MGI:98246]
Coordinates
chr2:66165708-66167151:-
Coord C1 exon
chr2:66167088-66167151
Coord A exon
chr2:66166462-66166603
Coord C2 exon
chr2:66165708-66165914
Length
142 bp
Sequences
Splice sites
3' ss Seq
TTCTTTTTCCCCATTTGCAGCCA
3' ss Score
10.19
5' ss Seq
CTGGTGAGA
5' ss Score
7.54
Exon sequences
Seq C1 exon
GATATCATTATTTCCTGGAGGGTGTTTTAGATGCACTGCTGTGTGGAAATAGCTCTGATGCAGG
Seq A exon
CCAATGTCCAGAAGGATATATGTGTGTAAAAGCTGGTAGAAACCCTAATTATGGTTACACAAGCTTTGATACCTTCAGTTGGGCATTTTTGTCCCTGTTTCGACTGATGACTCAGGACTTCTGGGAAAATCTATACCAACTG
Seq C2 exon
ACATTGCGTGCTGCTGGCAAAACCTACATGATATTTTTTGTGCTGGTCATTTTCTTGGGCTCATTCTACCTGATAAACTTGATCCTGGCTGTGGTGGCCATGGCCTATGAGGAGCAGAATCAGGCCACACTGGAGGAGGCTGAACAGAAAGAGGCAGAATTTCAGCAGATGTTGGAGCAACTTAAGAAGCAGCAAGAGGCTGCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000064329_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.246
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=FE(7.9=100)
A:
PF0052026=Ion_trans=FE(17.6=100)
C2:
PF0052026=Ion_trans=PD(11.6=44.9),PF0293211=Neur_chan_memb=PU(33.3=89.9)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGGAGGGTGTTTTAGATGCA
R:
TGCTGCTTCTTAAGTTGCTCCA
Band lengths:
245-387
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: