Special

MmuEX0046237 @ mm9

Exon Skipping

Gene
ENSMUSG00000035168 | Tanc1
Description
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 [Source:MGI Symbol;Acc:MGI:1914110]
Coordinates
chr2:59631153-59635809:+
Coord C1 exon
chr2:59631153-59631304
Coord A exon
chr2:59633852-59634083
Coord C2 exon
chr2:59635643-59635809
Length
232 bp
Sequences
Splice sites
3' ss Seq
ATGCCTCTGCCTCTCCACAGGTG
3' ss Score
13.06
5' ss Seq
ACGGTACCT
5' ss Score
6.79
Exon sequences
Seq C1 exon
CCTCAGATCCCACTCAGGACCTTCCTGGTACTCCATTACTCTCACCAAGTTCTTCTACAAGTGCTCTCAGTGTGACCAGAACACCTGCTGGGCCTGGGACTGCTGACAGCCAGAGACCGAGAGAGGATGCGGTGAAATACCTCGCTTCTAAG
Seq A exon
GTGGTGGCCTACCATTACTGCCAGGCTGACAACACTTACACATGTCTGGTACCTGAGTTTGTGCACAGCATTGCTGCTTTGCTGTGCCGGTCCCACCAGCTGGCTGCCTACAGAGACCTTCTGATCAAGGAACCCCAGCTGCAGAGCATGCTGAGCCTCCGCTCCTGTGTGCAGGATCCCGTGGCTGCTTTCAAGAGGGGCGTCCTGGAGCCACTTACAAGCCTAAGAAACG
Seq C2 exon
AGCAAAAAATTCCAGAAGAGGAGTATATCATCCTTATAGATGGCTTGAATGAAGCTGAGTTTCATAAGCCTGATTACGGAGATACGCTGTCTTCGTTTATTACCAAAATTATTCCTAAGTTCCCCACCTGGCTGAAGTTGATCGTGACCGTGAGAGCAAATTTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000035168_MULTIEX1-11/25=10-12
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.725 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF131911=AAA_16=PD(1.4=2.0)

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000036003





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000108187, ENSMUSP00000123345
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr2:159174953-159175184 
HIGH PSI
HsaEX6016144
(TANC1)
Human
(hg19)
chr2:160031464-160031695 
HIGH PSI
HsaEX6016144
(TANC1)
Rat
(rn6)
chr3:45868297-45868528 
ALTERNATIVE
RnoEX0088527
(Tanc1)
Cow
(bosTau6)
chr2:37289995-37290226 
HIGH PSI
BtaEX6009654
(TANC1)
Chicken
(galGal4)
chr7:36008602-36008833 
HIGH PSI
GgaEX0018990
(TANC1)
Chicken
(galGal3)
chr7:38144938-38145169 
HIGH PSI
GgaEX0018990
(TANC1)
Zebrafish
(danRer10)
chr6:11849955-11850186 
HIGH PSI
DreEX0077210
(tanc1a)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CCTCAGATCCCACTCAGGACC

				
R: 
GATCAACTTCAGCCAGGTGGG

				
Band lengths: 
295-527

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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