Special

MmuEX0049247 @ mm10

Exon Skipping

Gene
Description
TruB pseudouridine (psi) synthase family member 2 [Source:MGI Symbol;Acc:MGI:2442186]
Coordinates
chr2:29782120-29785027:-
Coord C1 exon
chr2:29784953-29785027
Coord A exon
chr2:29783312-29783373
Coord C2 exon
chr2:29782120-29782201
Length
62 bp
Sequences
Splice sites
3' ss Seq
AGGGTCTGGTTGCCTTTCAGTGC
3' ss Score
7.19
5' ss Seq
AAGGTATCG
5' ss Score
8.7
Exon sequences
Seq C1 exon
TACGTGGTCCAGCATTCACAAACCTGAAGATCGGTGTGGGACATCGCTTGGATGTCCAGGCTTCTGGTGTGCTTG
Seq A exon
TGCTCGCCGTGGGACATGGACGCAGCCTCCTCACTGACATGTATGATGCTCATCTCACCAAG
Seq C2 exon
GATTACACAGTGCGTGGCCTCCTGGGCAAAGCTACAGACAACTTCTGTGAAGATGGACGGCTGATAGAGAAGACAACGTATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000039826_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

Show structural model
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF0084917=PseudoU_synth_2=FE(16.4=100),PF0150913=TruB_N=PU(14.7=84.6)
A:
PF0084917=PseudoU_synth_2=FE(13.2=100),PF0150913=TruB_N=FE(13.3=100)
C2:
PF0084917=PseudoU_synth_2=FE(17.8=100),PF0150913=TruB_N=FE(18.0=100)


Main Inclusion Isoform:


Main Skipping Isoform:


Other Inclusion Isoforms:


Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
Chicken
(galGal3)
HIGH PSI
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGTGGTCCAGCATTCACAAA
R:
TCAGCCGTCCATCTTCACAGA
Band lengths:
138-200
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types