Special

MmuEX0052956 @ mm10

Exon Skipping

Gene
ENSMUSG00000024238 | Zeb1
Description
zinc finger E-box binding homeobox 1 [Source:MGI Symbol;Acc:MGI:1344313]
Coordinates
chr18:5591860-5705243:+
Coord C1 exon
chr18:5591860-5591967
Coord A exon
chr18:5641382-5641518
Coord C2 exon
chr18:5705043-5705243
Length
137 bp
Sequences
Splice sites
3' ss Seq
ACTCTTCTCTCCTCCTTCAGGAT
3' ss Score
12.6
5' ss Seq
AAGGTAAGC
5' ss Score
10.22
Exon sequences
Seq C1 exon
GGGAGGGAGGGAGGAGGTGACTCGAGCATTTAGACACAAGCGAGAGGATCATGGCGGATGGCCCCAGGTGTAAGCGCAGAAAGCAGGCGAACCCGCGGCGCAATAACG
Seq A exon
GATAATCTTAAGCTTCCACCACAAGAAGACTGTAGAGGTCCCTCCCGCACCAAGAACCTCCTGCAGATCTTTTTCAGTGTTCTTGGAGGTGGGCTGAGAGCTCGATCAGTTTGTGTCAGCCACCTTGTTCTCTAAAG
Seq C2 exon
TTACAAATTATAATACTGTGGTAGAAGCAAATTCAGATTCCGATGATGAAGACAAACTCCATATTGTGGAAGAAGAAAGTATTACAGATGCAGCTGACTGTGAAGGTGGCATGCCAGATGATGAACTGCCAGCAGACCAGACAGTATTACCAGGAGGCAGTGACAGGGGGGGCGGTGCCAAGAACTGCTGGCAAGACAACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024238_MULTIEX1-4/9=C1-5
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.993 A=1.000 C2=0.973
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000124507





     
                   









    
Main Skipping Isoform:
ENSMUSP00000025081





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000124395, ENSMUSP00000135125
  



Associated events







Other assemblies


mm9




Conservation


Human
(hg38)
chr10:31387124-31387266 
ALTERNATIVE
HsaEX0072568
(ZEB1)
Human
(hg19)
chr10:31676053-31676195 
ALTERNATIVE
HsaEX0072568
(ZEB1)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr13:34195150-34195289 
ALTERNATIVE
BtaEX0040896
(ZEB1)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CAGGTGTAAGCGCAGAAAGCA

				
R: 
TGTCTTGCCAGCAGTTCTTGG

				
Band lengths: 
242-379

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"