Special

MmuEX0053379 @ mm9

Exon Skipping

Gene
ENSMUSG00000070420 | Zfp498
Description
zinc finger protein 498 [Source:MGI Symbol;Acc:MGI:3647079]
Coordinates
chr5:146048177-146052338:+
Coord C1 exon
chr5:146048177-146048268
Coord A exon
chr5:146049163-146049286
Coord C2 exon
chr5:146051199-146052338
Length
124 bp
Sequences
Splice sites
3' ss Seq
GCAATCTCCTGTTGTTTCAGGGT
3' ss Score
8.65
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
Exon sequences
Seq C1 exon
CATTGCCCATTCTTCATGTGGGTCCAGGGCTTCCCTCTGTGAGTGCCAGAGACCAAGAGATGGCTGCTGGATTCCTTGCAGCCACGTCCCAG
Seq A exon
GGTCTGGGGCCATTTAAAGACATGACTTTGGGTTTTCCTGAGGAGGAATGGAGGCATGTAGCCCCAGCTCAGATTGACTGCTTTGGAGAATACGTGGACTCACAGGATTGTGGGGTCCTTCCAG
Seq C2 exon
GTGCTGGGAGCAAGGAGAAGGAGGCTAAGCCCCAGCAGGAAGACCTGAAGAGAGCATTTGTTGGGTTGACTTCCGATGGCTTTGGAGAAGCCGACATCCAGATTCCTGGACCAGGGGGCACCTGTGAGCAGGAGCCTGGGAGCTCTGGGACCAGTCTGCCTGGGCTTCCTGCTCCTCAGCATGGGGTACCCCTGCCTGACACCCTCAACACCCACAATTCTTTCTGGAAGCCTTTCCAGTGCCCTGAGTGTGGAAAAGGCTTTAGTCGGAGCTCCAACCTTGTTAGGCACCAGCGGACCCATGAAGAAGAAAAATCCTTTGGCTGTGTGGAGTGTGGGAAAGGTTTCACCCTGAGGGAATACCTCACCAAGCATCAGAGGACCCACCTGGGCAAGAGGCCCTATGTGTGTGGCGAGTGCTGGAAGACCTTCAGCCAGAGGCATCACCTGGAGGTGCACCAGCGTAGCCACACTGGGGAGAAGCCCTACAAGTGCTCAGAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000070420-'6-3,'6-2,7-3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.613 A=0.381 C2=0.373
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
PF0135222=KRAB=WD(100=81.0)

							
C2:
PF0009621=zf-C2H2=WD(100=8.3),PF134651=zf-H2C2_2=WD(100=9.4),PF134651=zf-H2C2_2=WD(100=9.4),PF134651=zf-H2C2_2=WD(100=9.0),PF134651=zf-H2C2_2=WD(100=9.4),PF134651=zf-H2C2_2=WD(100=9.4)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000091664





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr7:99624057-99624180 
ALTERNATIVE
HsaEX0073794
(ZSCAN25)
Human
(hg19)
chr7:99221680-99221803 
ALTERNATIVE
HsaEX0073794
(ZNF498)
Rat
(rn6)
chr12:11777809-11777932 
HIGH PSI
RnoEX0102299
(Zscan25)
Cow
(bosTau6)
chr25:37345206-37345332 
HIGH PSI
BtaEX0041641
(ZSCAN25)
Chicken
(galGal4)
chr2:541631-541757 
HIGH PSI
GgaEX1004758
([1])
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
AGAGATGGCTGCTGGATTCCT

				
R: 
ATTGTGGGTGTTGAGGGTGTC

				
Band lengths: 
255-379

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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