MmuEX6078352 @ mm10
Exon Skipping
Gene
ENSMUSG00000035580 | Kcnh8
Description
potassium voltage-gated channel, subfamily H (eag-related), member 8 [Source:MGI Symbol;Acc:MGI:2445160]
Coordinates
chr17:52950330-52959503:+
Coord C1 exon
chr17:52950330-52950368
Coord A exon
chr17:52956556-52956911
Coord C2 exon
chr17:52959397-52959503
Length
356 bp
Sequences
Splice sites
3' ss Seq
CTGTCCTATTCACTATCTAGGCA
3' ss Score
8.45
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
Exon sequences
Seq C1 exon
GTAATATCAAGATTATCGAACAAATCTACAGTCTCACAG
Seq A exon
GCAGAGCCCAAGGGGAATGGAAGCATCAACAAGAGACTCCCATCCATTGTGGAAGATGAGGAGGAAGAAGAGGTTGAGGAAGAGGAGACGACCTCCCTTTCTCCTATCTACACAAGGGGATCCTCTGTCTCACATAGCAAAAAGACTGGAAGCAATAAGACCTATCTAGGCTTGAGCTTAAAGCAACTGGCCTCAGGAACGGTACCATTCCACTCACCTATCAGAGTCTCCAGTGCCAACTCCCCTAAAACCAAGCAGGAAGCTGACCCACCTAACCATGGTAGAAAGAAAGAGAAGAACCTGAAAGTGCAGCTTTCCAGCCTGGGTAGTGCTGGAACCCCAGAGCTTAGTCCAAG
Seq C2 exon
GATTGTTGATGGAATTGAAGATGGTAACAGCAATGAGGAAACTCAGACTTTTGACTTTGGCTCTGAACAGATCAGGCCAGAGCCCAGGATTTCCCCTCCCCTTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000035580-'4-20,'4-16,15-20=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.769 A=0.899 C2=0.919
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 1 annotated functions for this event
PMID: 27453045
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, coimmunoprecipitation. ELM ID: ELMI003176; ELM sequence: LPSIVE; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types