Special

MmuEX6099828 @ mm10

Exon Skipping

Gene
ENSMUSG00000036040 | Adamtsl2
Description
ADAMTS-like 2 [Source:MGI Symbol;Acc:MGI:1925044]
Coordinates
chr2:27103868-27107539:+
Coord C1 exon
chr2:27103868-27104038
Coord A exon
chr2:27104749-27104925
Coord C2 exon
chr2:27107395-27107539
Length
177 bp
Sequences
Splice sites
3' ss Seq
TCCTGTTTGGCCCTTCTCAGTGC
3' ss Score
7.22
5' ss Seq
GAGGTGAGC
5' ss Score
8.7
Exon sequences
Seq C1 exon
TGCAGTGGGAGCTGTGGACAGGGCCGCACTATCAGGCATGTGTACTGTAAGACCAGCGATGGACGGGTAGTTCCCGAGTCTCAGTGCCAGACAGAGACAAAGCCTCTGGCTATCCACCCCTGTGGGGACAAGAACTGCCCAGCACACTGGCTGGCTCAAGACTGGGAAAGG
Seq A exon
TGCAATACCACCTGTGGGCGTGGTGTGAAAAAGCGGTTAGTTCTCTGCATGGAGCTGGCCAACGGAAAGCCTCAGATCCGCAGTGGCCCTGAATGCGGGTTAGCCAGGAAGCCCCCTGAGGAGAGCACGTGCTTCGAGAGGCCTTGCTTCAAGTGGTACACCAGCCCCTGGTCAGAG
Seq C2 exon
TGCACCAAAACATGTGGGGTAGGTGTGAGGATGCGAGACGTGAAGTGTTACCAGGGAACCGACATTGTCCGTGGATGTGACCCACTGGTGAAGCCTGTTGGCCGACAGGCTTGTGACTTGCAGCCATGCCCCACAGAGCCCCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000036040-'24-35,'24-32,32-35=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.017 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0009014=TSP_1=PD(81.8=78.9),PF0009014=TSP_1=PU(14.6=10.5)

							
A:
PF0009014=TSP_1=PD(80.5=55.9),PF0009014=TSP_1=PU(12.0=10.2)

							
C2:
PF0009014=TSP_1=PD(84.0=85.7)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000088774





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr9:133570331-133570507 
HIGH PSI
HsaEX6063764
(ADAMTSL2)
Human
(hg19)
chr9:136435453-136435629 
HIGH PSI
HsaEX6063764
(ADAMTSL2)
Rat
(rn6)
chr3:5650679-5650855 
HIGH PSI
RnoEX6016070
(Adamtsl2)
Cow
(bosTau6)
chr11:104502454-104502630 
HIGH PSI
BtaEX6047340
(ADAMTSL2)
Chicken
(galGal4)
chr17:6988765-6988941 
HIGH PSI
GgaEX7009825
(ADAMTSL2)
Chicken
(galGal3)
chr8:6403205-6403381 
ALTERNATIVE
GgaEX0005370
([1])
Zebrafish
(danRer10)
chr5:65212054-65212230 
HIGH PSI
DreEX0011315
(adamtsl2)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CTGTAAGACCAGCGATGGACG

				
R: 
CTGCAAGTCACAAGCCTGTCG

				
Band lengths: 
250-427

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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