MmuEX6101682 @ mm10
Exon Skipping
Gene
ENSMUSG00000057182 | Scn3a
Description
sodium channel, voltage-gated, type III, alpha [Source:MGI Symbol;Acc:MGI:98249]
Coordinates
chr2:65520823-65524209:-
Coord C1 exon
chr2:65524146-65524209
Coord A exon
chr2:65521792-65521933
Coord C2 exon
chr2:65520823-65521029
Length
142 bp
Sequences
Splice sites
3' ss Seq
ATTGCTTCTTTCTTTCCCAGACA
3' ss Score
9.85
5' ss Seq
TTGGTAGGG
5' ss Score
4.44
Exon sequences
Seq C1 exon
GCCACTTTTATGTTTTGGATGGACAAAAAGATCCTTTACTTTGTGGAAATGGGTCCGATGCAGG
Seq A exon
ACAATGTCCAGAAGGGTACATCTGTGTGAAGGCTGGACGAAACCCCAACTACGGTTACACGAGCTTTGACACATTTAGCTGGGCCTTCTTATCGCTGTTTCGACTCATGACTCAAGACTACTGGGAGAACCTTTACCAGTTG
Seq C2 exon
ACATTACGTGCAGCTGGGAAAACCTACATGATCTTTTTCGTCCTGGTAATTTTCTTGGGCTCATTTTATTTGGTGAACTTGATCCTGGCTGTGGTGGCCATGGCCTATGAGGAACAAAATCAGGCCACACTGGAGGAGGCTGAGCAGAAAGAGGCGGAGTTTCAGCAGATGTTGGAGCAGTTGAAAAAGCAGCAAGAGGAGGCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000057182-'12-14,'12-13,13-14=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.116
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=FE(7.8=100)
A:
PF0052026=Ion_trans=FE(17.5=100)
C2:
PF0052026=Ion_trans=PD(11.6=44.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCACTTTTATGTTTTGGATGGACA
R:
GCTGCTTTTTCAACTGCTCCA
Band lengths:
257-399
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types