MmuEX6101705 @ mm10
Exon Skipping
Gene
ENSMUSG00000075318 | Scn2a
Description
sodium channel, voltage-gated, type II, alpha [Source:MGI Symbol;Acc:MGI:98248]
Coordinates
chr2:65690045-65707360:+
Coord C1 exon
chr2:65690045-65690332
Coord A exon
chr2:65701717-65702064
Coord C2 exon
chr2:65707228-65707360
Length
348 bp
Sequences
Splice sites
3' ss Seq
TTCCTTTTGGTTCTTTCTAGTCT
3' ss Score
8.94
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
Exon sequences
Seq C1 exon
GCAGCAGCTGCAGCAGCGTCTGCAGAATCCAGAGACTTCAGTGGAGCAGGTGGGATAGGTGTTTTCTCGGAGAGTTCTTCCGTAGCTTCAAAGTTAAGTTCCAAGAGTGAAAAGGAGCTGAAAAACAGAAGGAAGAAAAAGAAACAGAAAGAGCAGGCTGGAGAGGAAGAGAAGGAAGATGCTGTGCGGAAATCTGCCTCTGAAGACAGCATACGAAAGAAAGGCTTCCGGTTTTCCCTAGAAGGGAGTAGACTGACCTACGAGAAGAGGTTTTCCTCTCCACACCAG
Seq A exon
TCTCTCTTGAGCATCCGAGGCTCCCTTTTTTCTCCGAGACGCAACAGTAGAGCAAGCCTTTTCAGCTTCAAAGGTCGGGTGAAGGATATTGGTTCTGAAAATGACTTTGCGGACGATGAACACAGCACGTTTGAGGACAACGACAGCAGGAGAGACTCTCTATTTGTACCACACAGACATGGAGAAAGGCGTCCCAGCAACGTTAGCCAGGCCAGCCGTGCCTCCCGGGGGATACCCACTCTACCCATGAATGGGAAGATGCACAGTGCAGTGGACTGCAACGGTGTGGTCTCCCTAGTTGGAGGCCCTTCTGCTCTCACATCTCCTGTGGGGCAGCTACTACCAGAG
Seq C2 exon
GGCACAACTACTGAAACAGAAATAAGGAAGAGGAGGTCCAGTTCTTACCATGTTTCTATGGACTTGTTGGAAGACCCTACATCAAGGCAAAGAGCAATGAGTATGGCCAGCATTTTGACCAACACTATGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000075318-'20-17,'20-16,23-17
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.324 A=0.598 C2=0.449
Domain overlap (PFAM):
C1:
PF0253517=Zip=PD(44.9=78.1),PF0043013=ATP-synt_B=PD(17.9=14.6),PF119333=DUF3451=PU(30.8=71.9)
A:
PF119333=DUF3451=FE(51.3=100)
C2:
PF119333=DUF3451=PD(16.5=82.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAGCAGGTGGGATAGGTGTT
R:
TGCTGGCCATACTCATTGCTC
Band lengths:
358-706
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types