Special

MmuINT0132035 @ mm9

Intron Retention

Gene
ENSMUSG00000070565 | Rasal2
Description
RAS protein activator like 2 [Source:MGI Symbol;Acc:MGI:2443881]
Coordinates
chr1:159088790-159091457:-
Coord C1 exon
chr1:159091256-159091457
Coord A exon
chr1:159088990-159091255
Coord C2 exon
chr1:159088790-159088989
Length
2266 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAAG
5' ss Score
9.06
3' ss Seq
AATGCTTGTTGTCCAATTAGGGT
3' ss Score
8.12
Exon sequences
Seq C1 exon
GTTTGGTAACAAAGAGGAGTACATGGCATTCATGAATGATTTTTTAGAACATGAATGGGGTGGAATGAAGCGGTTCCTTTTGGAGATCTCTAATCCTGACACCATCTCAAACACCCCAGGCTTCGATGGTTACATTGATTTGGGCAGAGAGCTGTCAGTTTTGCATTCCTTACTATGGGAAGTAGTTTCCCAACTTGATAAG
Seq A exon
GTAAAGTAGGAGGGAGGGTAGTGGGAAATGGGAGACACTGAACCTTAGTGTCCAGATTCTAGCAGACATCTGATAGCACACGACCTTTCTGCTGGCCAAGCGACCTTCCTTACTTTAGACATCAAAAGTAAATGATTAAGTGAGTAATGTACAGCCAAAATTCCTAGAGAGCCTTGGTATTACTAATATATGCTAGTGTTAAGTATAGAAAGAAAGTTTTCAGATATGTGCATGTATATACATATCTGAAACATATATATACATATTTACCCTGGCAGTGTATATATATATATATGTATATGTATATACATATATACATATCTGAAAACTTGCCTAGAAACTATTACCAAATACTAGAGTGAACATCTTTATCTGTGTGGGAGAAACTTCATCTAGTAATTTATAAGGACAAGAAGTTTTTTAAAAGTTCAAGTTTGTAAAATAATGTTCATCATATTTAAGCTAGCCTCACCATGGAGAAGTTGTTTTTCGACTATGTATGTCAGACTTGGATATAATTTTTAGCACTAAAAGCCATATAGCATCTAAAAGTGTGGATGTTTTCTTTATCTACCAATGTGAATTAAGAATACAAAAATAATTTATTTTTAATGACAAATGAACTTTGATTATTTTAATAACTGAATGTAAAGTATACCAGTCATTTTCTTCATTCTGAGGTCTTACAAAGAGGGGTAGATTCTGTAGTAGGAAATGGCTCAGTAATCGGTGTTATTTTTCTGTGATAAGGACTTACTTGTTTTCTTAAATTTTTCTCAACTATAAAATGTTATATATAATGTTGAGTAATAAACTTCTTAGTAAATTTCACTTTCTAGAATAAACATGTAGATGGAAGTATGTCCACTGGTACTTAAAATGTTTATAAAACCATAAACCATTCCATATTCTCCAAGAACTACATCTTACATCTCCACTTTGAAACATGCTAGGTAGATATTAAGTTGAAGTTATGTAGAAAGTAAATTCTTCTTTATGAATCTTAGCACTGTTGAGCAAGTAAAGGCATTTTTTAGATGACATTCATATCTAGTCTAACAGAGTAGAAGAGTCTTGTTAGTTGACTGGAGCGTGTAGCTAAGGGGTAGAGTACCTGCCTGGCATGCACAGAGCTAGGTTTGAATGCTAGCAATAAATGCATACAATAAATTCCATAAGAATACTTTCTCACCATGAATAATGCCCTAGGTTTGATTGCCAGACTCACATCACACACACACACATCTTATTGATCTTTGAGAAGCTAAAGAATCCCTAAAGGCAACCATGACTGTTGGGCTAAACTGCACAATGGTTGAGGATTCCATGAGAATCCACGAGGATAAGAATTGCACTAGGAATGCTGGATGAGGTGGTACAAACCTTGAATCCCTGTACTCGGAAGGCAGATAGGTGGATCTACCTGAATTTGAGACTAGCCTAGTCTAAAAGTATGTTCCAAGACAGACCAGACTACTAAAGCAATTATTTTAAAAAGTTGTTGTTAGCAATTATTTTTTGAAATAGATCTCATTCATTTATGAAGTCTCTTTTAATACATTTTTCTGTGTAAGCACATTTCTTCATTTTTAATCTTTGGTCCTGGGAACTAGAAGTTTAGGCATATCCGAGAAGAGTGAAAGATGATGTGATTCTCCTGGTTTGTTTGGTTTGGATGGTTAGCAGGAGACTCAGTTGACAGTGAGTCGAGCTGCCTGAGATGAAGTGGATAGTGGGTTGTAGTGTAAGCTAACCACACACCCTGCAGTCTCTGCCCCAGGCAGCTCCTTCTGTATGTTGGCATGCACTGCTTTCCTCACATCATCCTTTCTCTTTGGAAACTTCATCACACAAGCCAATCATCTGATCCTCAAGTTTCTTTCGGTTAGAAGGTGTTTGGTTCTTCCGTTTCCCTCTCCATCTTGGTCTGGTAGTCACTCAAAGCCTTAGTGTGCTTTGCATGCATATTTTAGTCGGAATGGCAATTGTTTGTTTGTTTGTTTGTTTGTTTTGAGCATGTCTTTTAATTTTTATTTGCATAATCCTAATTTCTATTTCTTTCTTTCCTCAATGTCTACTGCACCTTGTTTCGCCTCCTCCATTCATCTCGACGCCATGGTTCCGCTGCTCCATAACAATGCATTATGAACTTGCCACTCCCATATACAATACCTACCCTCCCTCCAACCTACATCCTTCCGTCAATGGGCATCATTGTCCCAAAAACAATATGTTGTGGATATCACAATGCTTGTTGTCCAATTAG
Seq C2 exon
GGTGAAAATTCCTTTCTACAGGCAACTGTGGCAAAACTGGGACCTCTCCCTCGTGTTCTTGCTGACATTACCAAGTCTCTGACTAATCCTACGCCAATACAGCAGCAGCTAAGACGTTTCGCTGAGCACAGCTCCAGTCCAAACGTCAGCGGAAGCCTCTCCTCTGGGCTGCAGAGAATATGTGAAGACCCCACTGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000070565-Rasal2:NM_177644:12
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.436
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NA

							
C2:
PF120043=DUF3498=PU(9.4=70.1)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000077423f5413A





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000077423, ENSMUSP00000114964, ENSMUSP00000117176
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr1:178454649-178456699 
ALTERNATIVE
HsaINT0137700
(RASAL2)
Human
(hg19)
chr1:178423784-178425834 
ALTERNATIVE
HsaINT0137700
(RASAL2)
Rat
(rn6)
chr13:74796811-74799223 
ALTERNATIVE
RnoINT0124509
(Rasal2)
Cow
(bosTau6)
chr16:61291704-61293749 
ALTERNATIVE
BtaINT0122615
(RASAL2)
Chicken
(galGal4)
chr8:6441842-6444376 
ALTERNATIVE
GgaINT0038836
(RASAL2)
Chicken
(galGal3)
chr8:6767515-6770070 
ALTERNATIVE
GgaINT0038836
(RASAL2)
Zebrafish
(danRer10)
chr2:35857342-35859470 
ALTERNATIVE
DreINT0124794
(rasal2)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"