Special

FBgn0000038 @ dm6

Biotype
protein_coding
Gene Symbol
nAChRbeta1
Description
The gene nicotinic Acetylcholine Receptor beta1 is referred to in FlyBase by the symbol Dmel AChRbeta1 (CG11348, FBgn0000038). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:4429349..4435993. Its molecular function is described by: acetylcholine-gated cation-selective channel activity; transmembrane signaling receptor activity; neurotransmitter receptor activity. It is involved in the biological process described with 6 unique terms, many of which group under: signaling; cellular process; synaptic signaling; cell communication; anterograde trans-synaptic signaling. 15 alleles are reported. No phenotypic data is available. The phenotypic classes of alleles include: viable; partially lethal - majority die; some die during pupal stage; short lived. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
Coordinates
chr3L:4429349-4435993:+
Assembly

GENOMIC BROWSER[edit]


EXPRESSION VALUES[edit]


SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Alternative 3'ss
63
chr3L:4433305-4433367
+
95.9
81.48
0
Alternative 3'ss
464
chr3L:4432904-4433367
+
3.32
81.48
0
Intron Retention
63
chr3L:4429503-4429565
+
20.29
100
0
Intron Retention
2670
chr3L:4429716-4432385
+
31.77
83.78
0
Intron Retention
782
chr3L:4432523-4433304
+
38.1
98.9
0
Intron Retention
155
chr3L:4433460-4433614
+
38.88
87.24
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000108556 CHRNE 1-to-4
Human hg38 ENSG00000135902 CHRND 1-to-4
Human hg38 ENSG00000170175 CHRNB1 1-to-4
Human hg38 ENSG00000196811 CHRNG 1-to-4
Human hg19 ENSG00000108556 CHRNE 1-to-4
Human hg19 ENSG00000135902 CHRND 1-to-4
Human hg19 ENSG00000170175 CHRNB1 1-to-4
Human hg19 ENSG00000196811 CHRNG 1-to-4
Mouse mm10 ENSMUSG00000014609 Chrne 1-to-4
Mouse mm10 ENSMUSG00000026251 Chrnd 1-to-4
Mouse mm10 ENSMUSG00000026253 Chrng 1-to-4
Mouse mm10 ENSMUSG00000041189 Chrnb1 1-to-4
Mouse mm9 ENSMUSG00000014609 Chrne 1-to-4
Mouse mm9 ENSMUSG00000026251 Chrnd 1-to-4
Mouse mm9 ENSMUSG00000026253 Chrng 1-to-4
Mouse mm9 ENSMUSG00000041189 Chrnb1 1-to-4
Rat rn6 ENSRNOG00000003777 Chrne 1-to-3
Rat rn6 ENSRNOG00000014698 Chrnb1 1-to-3
Rat rn6 ENSRNOG00000019527 Chrnd 1-to-3
Cow bosTau6 ENSBTAG00000004908 CHRNE 1-to-4
Cow bosTau6 ENSBTAG00000011390 CHRND 1-to-4
Cow bosTau6 ENSBTAG00000019242 CHRNB1 1-to-4
Cow bosTau6 ENSBTAG00000045943 CHRNG 1-to-4
Chicken galGal4 ENSGALG00000007899 CHRND 1-to-2
Chicken galGal4 ENSGALG00000007906 CHRNG 1-to-2
Chicken galGal3 ENSGALG00000007899 F1NJ26_CHICK 1-to-2
Chicken galGal3 ENSGALG00000007906 F1NJ22_CHICK 1-to-2
Zebrafish danRer10 ENSDARG00000019342 chrnd 1-to-5
Zebrafish danRer10 ENSDARG00000022532 chrnb1l 1-to-5
Zebrafish danRer10 ENSDARG00000034307 chrne 1-to-5
Zebrafish danRer10 ENSDARG00000069660 chrnb1 1-to-5
Zebrafish danRer10 ENSDARG00000086647 chrng 1-to-5