Special

FBgn0004118 @ dm6

Biotype
protein_coding
Gene Symbol
nAChRbeta2
Description
The gene nicotinic Acetylcholine Receptor beta2 is referred to in FlyBase by the symbol Dmel AChRbeta2 (CG6798, FBgn0004118). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3R:24509228..24515106. Its molecular function is described by: acetylcholine-gated cation-selective channel activity; neurotransmitter receptor activity; transmembrane signaling receptor activity. It is involved in the biological process described with 7 unique terms, many of which group under: cellular process; biological regulation; cell communication; response to stimulus; synaptic signaling. 19 alleles are reported. The phenotype of these alleles manifest in: chaeta. The phenotypic classes of alleles include: flight defective; chemical resistant; visible; lethal; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.
Coordinates
chr3R:24509228-24515106:-
Assembly
dm6

GENOMIC BROWSER[edit]

EXPRESSION VALUES[edit]

SPECIAL DATASETS

  • Neural diversity
  • Neurogenesis
  • Neuronal activity
  • Splicing factor regulation (brain)
  • Splicing factor regulation (SL2)

EVENTS AND AS PROFILES[edit]

Associated events[edit]

Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Exon Skipping
194
chr3R:24514494-24514687
-
99.37
26.23
0
Exon Skipping
107
chr3R:24510141-24510247
-
94.44
40.96
0
Intron Retention
2035
chr3R:24511660-24513694
-
26.82
87.4
0
Intron Retention
258
chr3R:24511226-24511483
-
14.49
61.89
0
Intron Retention
91
chr3R:24510982-24511072
-
13.55
67.69
0



Orthologous genes[edit]

Organism Assembly Gene ID Gene Name Orthology Type

Human hg38 ENSG00000101204 CHRNA4 5-to-9
Human hg38 ENSG00000117971 CHRNB4 5-to-9
Human hg38 ENSG00000120903 CHRNA2 5-to-9
Human hg38 ENSG00000138435 CHRNA1 5-to-9
Human hg38 ENSG00000147434 CHRNA6 5-to-9
Human hg19 ENSG00000101204 CHRNA4 5-to-9
Human hg19 ENSG00000117971 CHRNB4 5-to-9
Human hg19 ENSG00000120903 CHRNA2 5-to-9
Human hg19 ENSG00000138435 CHRNA1 5-to-9
Human hg19 ENSG00000147434 CHRNA6 5-to-9
Mouse mm10 ENSMUSG00000022041 Chrna2 5-to-9
Mouse mm10 ENSMUSG00000027950 Chrnb2 5-to-9
Mouse mm10 ENSMUSG00000031492 Chrnb3 5-to-9
Mouse mm10 ENSMUSG00000032303 Chrna3 5-to-9
Mouse mm10 ENSMUSG00000035200 Chrnb4 5-to-9
Mouse mm9 ENSMUSG00000022041 Chrna2 5-to-9
Mouse mm9 ENSMUSG00000027950 Chrnb2 5-to-9
Mouse mm9 ENSMUSG00000031492 Chrnb3 5-to-9
Mouse mm9 ENSMUSG00000032303 Chrna3 5-to-9
Mouse mm9 ENSMUSG00000035200 Chrnb4 5-to-9
Rat rn6 ENSRNOG00000012283 Chrna6 5-to-9
Rat rn6 ENSRNOG00000013829 Chrna3 5-to-9
Rat rn6 ENSRNOG00000017424 Chrna2 5-to-9
Rat rn6 ENSRNOG00000018286 Chrna1 5-to-9
Rat rn6 ENSRNOG00000020778 Chrnb2 5-to-9
Cow bosTau6 ENSBTAG00000002252 CHRNA2 5-to-9
Cow bosTau6 ENSBTAG00000013657 CHRNA5 5-to-9
Cow bosTau6 ENSBTAG00000014050 CHRNB3 5-to-9
Cow bosTau6 ENSBTAG00000014056 CHRNA6 5-to-9
Cow bosTau6 ENSBTAG00000018253 CHRNA1 5-to-9
Chicken galGal4 ENSGALG00000003005 CHRNB4 5-to-9
Chicken galGal4 ENSGALG00000003021 CHRNA5 5-to-9
Chicken galGal4 ENSGALG00000005801 CHRNA4 5-to-9
Chicken galGal4 ENSGALG00000015384 CHRNB3 5-to-9
Chicken galGal4 ENSGALG00000016565 CHRNA2 5-to-9
Chicken galGal3 ENSGALG00000003005 F1NWX4_CHICK 5-to-9
Chicken galGal3 ENSGALG00000003021 F1NIT6_CHICK 5-to-9
Chicken galGal3 ENSGALG00000005801 ACHA4_CHICK 5-to-9
Chicken galGal3 ENSGALG00000015384 F1NA49_CHICK 5-to-9
Chicken galGal3 ENSGALG00000016565 F1N9F1_CHICK 5-to-9
Zebrafish danRer10 ENSDARG00000003420 chrna5 5-to-14
Zebrafish danRer10 ENSDARG00000006602 chrna2a 5-to-14
Zebrafish danRer10 ENSDARG00000038508 chrnb3b 5-to-14
Zebrafish danRer10 ENSDARG00000052764 chrnb3a 5-to-14
Zebrafish danRer10 ENSDARG00000057025 chrna2b 5-to-14
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