BtaEX6046460 @ bosTau6
Exon Skipping
Gene
ENSBTAG00000015327 | SPTAN1
Description
spectrin, alpha, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11273]
Coordinates
chr11:99159322-99161264:+
Coord C1 exon
chr11:99159322-99159519
Coord A exon
chr11:99159623-99159769
Coord C2 exon
chr11:99161161-99161264
Length
147 bp
Sequences
Splice sites
3' ss Seq
ATCCCTCTCCCCTTCTTTAGCTG
3' ss Score
9.6
5' ss Seq
CAGGTAGGG
5' ss Score
9.46
Exon sequences
Seq C1 exon
GAACACCGGACAGAAATTGATGCCAGAGCTGGCACTTTCCAGGCATTCGAGCAGTTTGGGCAGCAGCTGTTGGCTCATGGGCACTACGCCAGCCCCGAGATCAAGGAGAAGCTCGATGTTCTAGACCAGGAGCGTGCAGACCTTGAGAAGGCCTGGGTCCAGCGCAGGATGATGCTGGATCAGTGCCTTGAATTGCAG
Seq A exon
CTGTTCCATCGGGATTGCGAGCAGGCCGAGAACTGGATGGCTGCCCGAGAGGCCTTTCTGAACACAGAAGACAAAGGGGACTCGCTAGACAGTGTGGAGGCTCTGATCAAAAAACACGAGGACTTTGATAAAGCAATTAATGTCCAG
Seq C2 exon
GAGGAGAAGATTGCTGCCCTGCAGTCCTTTGCTGACCAGCTCATCGCTGGTGGCCACTACGCCAAAGGCGACATCTCCAGCCGGCGCAATGAGGTTCTGGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSBTAG00000015327-'37-40,'37-39,38-40=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.061 A=0.020 C2=0.000
Domain overlap (PFAM):
C1:
PF0043516=Spectrin=PD(57.1=90.9),PF0043516=Spectrin=PU(2.9=4.5)
A:
PF0043516=Spectrin=FE(45.7=100)
C2:
PF0043516=Spectrin=FE(32.4=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTTCCAGGCATTCGAGCAGT
R:
CTGGAGATGTCGCCTTTGGC
Band lengths:
244-391
Functional annotations
There are 1 annotated functions for this event
PMID: 9712874
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: classical fluorescence spectroscopy, cleavage reaction, glutathione s tranferase tag, western blot. ELM ID: ELMI001910; ELM sequence: DSLDS; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]